Effects of IKAP/hELP1 deficiency on gene expression in differentiating neuroblastoma cells: implications for familial dysautonomia (Q33895169)

29 July 2017

title

Effects of IKAP/hELP1 deficiency on gene expression in differentiating neuroblastoma cells: implications for familial dysautonomia (English)

1 reference

differentiating neuroblastoma

29 July 2017

main subject

1 reference

1 reference

Metsada Pasmanik-Chor

series ordinal

2

object named as

Metsada Pasmanik-Chor

1 reference

29 July 2017

Rachel Cohen-Kupiec

1

1 reference

29 July 2017

Varda Oron-Karni

series ordinal

3

1 reference

29 July 2017

Miguel Weil

series ordinal

4

1 reference

29 July 2017

language of work or name

English

0 references

publication date

29 April 2011

1 reference

29 July 2017

1 reference

29 July 2017

volume

6

1 reference

29 July 2017

issue

4

1 reference

29 July 2017

page(s)

e19147

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

29 April 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

IKAP/Elp1 involvement in cytoskeleton regulation and implication for familial dysautonomia

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Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells

5 July 2018

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IKAP/hELP1 down-regulation in neuroblastoma cells causes enhanced cell adhesion mediated by contactin overexpression.

5 July 2018

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Cell signaling by receptor tyrosine kinases

5 July 2018

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The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation

5 July 2018

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Identification of an RNA-dependent RNA polymerase in Drosophila establishes a common theme in RNA silencing.

5 July 2018

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Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs.

5 July 2018

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5 July 2018

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Loss-of-function of IKAP/ELP1: could neuronal migration defect underlie familial dysautonomia?

5 July 2018

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To adhere or not to adhere: the role of Cadherins in neural crest development

5 July 2018

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Comprehensive characterization of neuroblastoma cell line subtypes reveals bilineage potential similar to neural crest stem cells

5 July 2018

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Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin

5 July 2018

1 reference

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Loss of mouse Ikbkap, a subunit of elongator, leads to transcriptional deficits and embryonic lethality that can be rescued by human IKBKAP.

5 July 2018

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Disease causing mutations of calcium channels

5 July 2018

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Extracellular matrix of the central nervous system: from neglect to challenge

5 July 2018

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5 July 2018

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The role of neurotrophins in axonal growth, guidance, and regeneration

5 July 2018

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Elongator complex: how many roles does it play?

5 July 2018

1 reference

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Functional biology of the alpha(2)delta subunits of voltage-gated calcium channels

5 July 2018

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Calsyntenin-1 docks vesicular cargo to kinesin-1

5 July 2018

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Transcription impairment and cell migration defects in elongator-depleted cells: implication for familial dysautonomia

5 July 2018

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Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells.

5 July 2018

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Regulating the dynamics of EGF receptor signaling in space and time

5 July 2018

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RET tyrosine kinase signaling in development and cancer

5 July 2018

1 reference

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The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches

5 July 2018

1 reference

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Semaphorin 5A is a bifunctional axon guidance cue regulated by heparan and chondroitin sulfate proteoglycans

5 July 2018

1 reference

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Induction of the neural crest and the opportunities of life on the edge.

5 July 2018

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Control of axonal branching and synapse formation by focal adhesion kinase

5 July 2018

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Guidance cues involved in the development of the peripheral autonomic nervous system

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084765

5 July 2018

Familial dysautonomia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084765

Axon Guidance by Growth Cones and Branches: Common Cytoskeletal and Signaling Mechanisms

5 July 2018

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Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance

5 July 2018

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5 July 2018

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Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family

5 July 2018

1 reference

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The calsyntenins--a family of postsynaptic membrane proteins with distinct neuronal expression patterns

5 July 2018

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Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen

5 July 2018

1 reference

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Purification and characterization of the human elongator complex

5 July 2018

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5 July 2018

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5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084765

Familial dysautonomia is caused by mutations of the IKAP gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084765

Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084765

Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells

5 July 2018

1 reference

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A striking organization of a large family of human neural cadherin-like cell adhesion genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084765

III. Role Of the RET signal transduction pathway in development of the mammalian enteric nervous system.

5 July 2018

1 reference

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Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology

5 July 2018

1 reference

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Identification of human cadherin-14, a novel neurally specific type II cadherin, by protein interaction cloning

5 July 2018

1 reference

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5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084765

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084765

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5 July 2018

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5 July 2018

1 reference

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5 July 2018

1 reference

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Cloning, characterization, and genomic structure of the mouse Ikbkap gene

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019147

IKAP/hELP1 deficiency in the cerebrum of familial dysautonomia patients results in down regulation of genes involved in oligodendrocyte differentiation and in myelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019147

Elongator – an emerging role in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019147

Conserved and divergent roles for members of the Snail family of transcription factors in the chick and mouse embryo

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084765

Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation

29 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0019147

SnapShot: EGFR signaling pathway

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21559466

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21559466

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Bone mineral density and metabolism in familial dysautonomia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21559466

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0019147

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference