Therapeutically targeting neuroinflammation and microglia after acute ischemic stroke. (Q33893264)

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11 March 2020

review article

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title

Therapeutically targeting neuroinflammation and microglia after acute ischemic stroke (English)

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11 March 2020

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12 October 2019

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12 October 2019

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12 October 2019

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1

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11 March 2020

Hyeon-Gu Yeo

4

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11 March 2020

Hong J Lee

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11 March 2020

author name string

Sang-Rae Lee

2

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11 March 2020

Sung S Choi

3

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11 March 2020

Kyu-Tae Chang

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publication date

25 June 2014

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12 September 2019

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BioMed Research International

11 March 2020

published in

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22 March 2019

25 April 2019

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12 September 2019

12 October 2019

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11 March 2020

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2014

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11 March 2020

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Creative Commons Attribution 3.0 Unported

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cites work

Tetrahydroxystilbene glucoside attenuates neuroinflammation through the inhibition of microglia activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Propofol protects against focal cerebral ischemia via inhibition of microglia-mediated proinflammatory cytokines in a rat model of experimental stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Kalopanaxsaponin A Exerts Anti-Inflammatory Effects in Lipopolysaccharide-Stimulated Microglia via Inhibition of JNK and NF-κB/AP-1 Pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglial responses after ischemic stroke and intracerebral hemorrhage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Role of inflammation and its mediators in acute ischemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Neuroprotective efficacy of subcutaneous insulin-like growth factor-I administration in normotensive and hypertensive rats with an ischemic stroke.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia and ischemic stroke: a double-edged sword

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Inhibition of Neuroinflammation in LPS-Activated Microglia by Cryptolepine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia: key elements in neural development, plasticity, and pathology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

N9 microglial cells polarized by LPS and IL4 show differential responses to secondary environmental stimuli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

TGFβ signalling plays an important role in IL4-induced alternative activation of microglia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

TIPE2, a novel regulator of immunity, protects against experimental stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Inflammatory cytokines in experimental and human stroke.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

The immunology of stroke: from mechanisms to translation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Astrocytes: targets for neuroprotection in stroke.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Fate mapping analysis reveals that adult microglia derive from primitive macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

The science of stroke: mechanisms in search of treatments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia in ischemic brain injury

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia transplantation attenuates white matter injury in rat chronic ischemia model via matrix metalloproteinase-2 inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia: gatekeepers of central nervous system immunology.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Cell adhesion molecules and ischemic stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Inflammation and the neurovascular unit in the setting of focal cerebral ischemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Systemic infection, inflammation and acute ischemic stroke.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Debris clearance by microglia: an essential link between degeneration and regeneration.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Acute ischaemic stroke and infection: recent and emerging concepts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Neurovascular signalling defects in neurodegeneration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

A rose by any other name? The potential consequences of microglial heterogeneity during CNS health and disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

The inflammatory response in stroke

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia in cerebral ischemia: molecular actions and interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

ATP mediates rapid microglial response to local brain injury in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia expressing interleukin-13 undergo cell death and contribute to neuronal survival in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Visualising microglial activation in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Role of IL-1alpha and IL-1beta in ischemic brain damage.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

CD45: new jobs for an old acquaintance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia-specific localisation of a novel calcium binding protein, Iba1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Glial expression of cytokines in the brains of cerebrovascular disease patients.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Distribution profile and properties of peripheral-type benzodiazepine receptors on human hemopoietic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Microglia as a unique cellular target in the treatment of stroke: potential neurotoxic mediators produced by activated microglia.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Characterization of benzodiazepine binding sites in cultured cells of neural origin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4095830

Human and economic burden of stroke

5 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Proliferating resident microglia after focal cerebral ischaemia in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Galectin-3 is required for resident microglia activation and proliferation in response to ischemic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Microglial cell activation and proliferation precedes the onset of CNS autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Heterogeneity of the microglial response in photochemically induced focal ischemia of the rat cerebral cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Neuroinflammation extends brain tissue at risk to vital peri-infarct tissue: a double tracer [11C]PK11195- and [18F]FDG-PET study

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Multiparametric assessment of acute and subacute ischemic neuronal damage: a small animal positron emission tomography study with rat photochemically induced thrombosis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

MRI monitoring of neuroinflammation in mouse focal ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Recombinant C1 inhibitor in brain ischemic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Inhibition of MMP-3 or -9 suppresses lipopolysaccharide-induced expression of proinflammatory cytokines and iNOS in microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Lipoxin A4 analogue protects brain and reduces inflammation in a rat model of focal cerebral ischemia reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Pretreatment with rosuvastatin protects against focal cerebral ischemia/reperfusion injury in rats through attenuation of oxidative stress and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

In vivo over-expression of interleukin-10 increases resistance to focal brain ischemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F297241

Brain macrophages: evaluation of microglia and their functions

21 January 2018

1 reference

12 December 2020

Immunocytochemical studies of cellular reaction in human ischemic brain stroke. MAB anti-CD68 stains macrophages, astrocytes and microglial cells in infarcted area

1 reference

12 December 2020

Flow cytometric analysis of inflammatory cells in ischemic rat brain

1 reference

12 December 2020

Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells

1 reference

12 December 2020

Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain

1 reference

12 December 2020

Geniposide reduces inflammatory responses of oxygen-glucose deprived rat microglial cells via inhibition of the TLR4 signaling pathway

1 reference

12 December 2020

Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice

1 reference

12 December 2020

Evolution of microglial activation in patients after ischemic stroke: a [11C](R)-PK11195 PET study

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/297241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25089266%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25089266%20AND%20SRC:MED&resulttype=core&format=json

11 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25089266%20AND%20SRC:MED&resulttype=core&format=json