Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety (Q33889911)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20032541%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety (English)

1 reference

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15 January 2020

0 references

1 reference

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4

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15 January 2020

6

Betsy C Herold

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15 January 2020

author name string

Sarah S Wilson

1

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15 January 2020

Natalia Cheshenko

2

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15 January 2020

Esra Fakioglu

3

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15 January 2020

Marla J Keller

5

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15 January 2020

publication date

1 January 2009

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15 January 2020

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15 January 2020

volume

14

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15 January 2020

issue

8

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15 January 2020

page(s)

1113-1124

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Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety

15 January 2020

cites work

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Glycerol monolaurate prevents mucosal SIV transmission

5 July 2018

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Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

5 July 2018

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Alternative entry receptors for herpes simplex virus and their roles in disease

5 July 2018

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Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission

5 July 2018

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IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3.

5 July 2018

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Microbicide trial screeches to a halt

5 July 2018

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A comprehensive murine model to evaluate topical vaginal microbicides: mucosal inflammation and susceptibility to genital herpes as surrogate markers of safety

5 July 2018

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Access to nectin favors herpes simplex virus infection at the apical surface of polarized human epithelial cells

5 July 2018

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Innate host defense of human vaginal and cervical mucosae.

5 July 2018

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Fourteen-day safety and acceptability study of 6% cellulose sulfate gel: a randomized double-blind Phase I safety study

5 July 2018

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Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission

5 July 2018

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Cervicovaginal secretions contribute to innate resistance to herpes simplex virus infection

5 July 2018

1 reference

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Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action.

5 July 2018

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Transcriptional regulation of beta-defensin-2 by lipopolysaccharide in cultured human cervical carcinoma (HeLa) cells.

5 July 2018

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Genital herpes and human immunodeficiency virus: double trouble

5 July 2018

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Activity of alpha- and theta-defensins against primary isolates of HIV-1

5 July 2018

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Alpha-defensins inhibit HIV infection of macrophages through upregulation of CC-chemokines

5 July 2018

1 reference

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Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread

5 July 2018

1 reference

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Mouse model of cervicovaginal toxicity and inflammation for preclinical evaluation of topical vaginal microbicides

5 July 2018

1 reference

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In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosa

5 July 2018

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Human immunodeficiency virus acquisition associated with genital ulcer disease and herpes simplex virus type 2 infection: a nested case-control study in Rakai, Uganda

5 July 2018

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Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication

5 July 2018

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Progesterone increases susceptibility and decreases immune responses to genital herpes infection

5 July 2018

1 reference

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Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial

5 July 2018

1 reference

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The molecular basis of nonoxynol-9-induced vaginal inflammation and its possible relevance to human immunodeficiency virus type 1 transmission

5 July 2018

1 reference

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Expression of mammalian defensin genes

5 July 2018

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Safety of multiple daily applications of COL-1492, a nonoxynol-9 vaginal gel, among female sex workers. COL-1492 Phase II Study Group

5 July 2018

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Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation

5 July 2018

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Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor

5 July 2018

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Gene expression, immunolocalization, and secretion of human defensin-5 in human female reproductive tract

5 July 2018

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Human beta-defensin-1: an antimicrobial peptide of urogenital tissues

5 July 2018

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Ultrastructure of cyclic changes in the murine uterus, cervix, and vagina

5 July 2018

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Association of cervical ectopy with heterosexual transmission of human immunodeficiency virus: results of a study of couples in Nairobi, Kenya

5 July 2018

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Human alpha- and beta-defensins block multiple steps in herpes simplex virus infection

5 July 2018

1 reference

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Role of IFN-alpha/beta signaling in the prevention of genital herpes virus type 2 infection.

29 October 2018

1 reference

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Nested case-control study of cervical mucosal lesions, ectopy, and incident HIV infection among women in Cape Town, South Africa

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879645

Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879645

Glycoprotein B plays a predominant role in mediating herpes simplex virus type 2 attachment and is required for entry and cell-to-cell spread

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879645

Decreased vaginal disease in J-chain-deficient mice following herpes simplex type 2 genital infection.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879645

Nonoxynol-9 enhances rectal infection by herpes simplex virus in mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2879645

Scientists rethink approach to HIV gels

29 October 2018

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12 December 2020

HIV vaccine failure prompts Merck to halt trial

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12 December 2020

AIDS research. Promising AIDS vaccine's failure leaves field reeling

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12 December 2020

Comparison of vaginal tolerance tests of spermicidal preparations in rabbits and monkeys

1 reference

12 December 2020

Roles for CXC chemokine ligands 10 and 11 in recruiting CD4+ T cells to HIV-1-infected monocyte-derived macrophages, dendritic cells, and lymph nodes

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12 December 2020

Identifiers

DOI

10.3851/IMP1463

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20032541%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20032541%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

20032541

1 reference