Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy. (Q33884161)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15988035%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy (English)

1 reference

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alternative mRNA splicing, via spliceosome

13 January 2020

main subject

1 reference

1

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13 January 2020

author name string

George Taffet

2

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13 January 2020

Craig Hartley

3

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13 January 2020

Debra L Kearney

4

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13 January 2020

Thomas A Cooper

5

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13 January 2020

language of work or name

English

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publication date

1 July 2005

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13 January 2020

number of pages

12

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Molecular and Cellular Biology

inferred from page(s)

published in

1 reference

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13 January 2020

volume

25

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13 January 2020

issue

14

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13 January 2020

page(s)

6267-6278

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Transgenic mice expressing CUG-BP1 reproduce splicing mis-regulation observed in myotonic dystrophy.

13 January 2020

cites work

1 reference

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Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development

5 July 2018

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Identification of putative new splicing targets for ETR-3 using sequences identified by systematic evolution of ligands by exponential enrichment

5 July 2018

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ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle

5 July 2018

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Finishing the euchromatic sequence of the human genome

5 July 2018

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Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure

5 July 2018

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5 July 2018

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Multiple domains control the subcellular localization and activity of ETR-3, a regulator of nuclear and cytoplasmic RNA processing events

5 July 2018

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ETR-3 and CELF4 protein domains required for RNA binding and splicing activity in vivo

5 July 2018

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Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart

5 July 2018

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CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing

5 July 2018

1 reference

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Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays

5 July 2018

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A functional deadenylation assay identifies human CUG-BP as a deadenylation factor

5 July 2018

1 reference

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Roles of cardiac transcription factors in cardiac hypertrophy

5 July 2018

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Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation.

5 July 2018

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Pre-mRNA splicing and human disease

5 July 2018

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Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2

5 July 2018

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Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells

5 July 2018

1 reference

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Loss of the muscle-specific chloride channel in type 1 myotonic dystrophy due to misregulated alternative splicing

5 July 2018

1 reference

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Expression and mutation analysis of BRUNOL3, a candidate gene for heart and thymus developmental defects associated with partial monosomy 10p

5 July 2018

1 reference

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Noninvasive cardiovascular phenotyping in mice

5 July 2018

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c-Jun ARE targets mRNA deadenylation by an EDEN-BP (embryo deadenylation element-binding protein)-dependent pathway

5 July 2018

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Molecular basis for impaired muscle differentiation in myotonic dystrophy

5 July 2018

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Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival

5 July 2018

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Genomic organization and isoform-specific tissue expression of human NAPOR (CUGBP2) as a candidate gene for familial arrhythmogenic right ventricular dysplasia

5 July 2018

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Androgens regulate the mammalian homologues of invertebrate sex determination genes tra-2 and fox-1

5 July 2018

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Gene structure prediction and alternative splicing analysis using genomically aligned ESTs

5 July 2018

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Alternative splicing: increasing diversity in the proteomic world

5 July 2018

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The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing

5 July 2018

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A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator

5 July 2018

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5 July 2018

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Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy

5 July 2018

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Knockout and knockin of the beta1 exon D define distinct roles for integrin splice variants in heart function and embryonic development

5 July 2018

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EDEN and EDEN-BP, a cis element and an associated factor that mediate sequence-specific mRNA deadenylation in Xenopus embryos.

5 July 2018

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A role for the putative tumor suppressor Bin1 in muscle cell differentiation

5 July 2018

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Muscle beta1D integrin reinforces the cytoskeleton-matrix link: modulation of integrin adhesive function by alternative splicing.

5 July 2018

1 reference

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Nucleocytoplasmic transport: signals, mechanisms and regulation

5 July 2018

1 reference

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Developmental regulation of myosin gene expression in mouse cardiac muscle

5 July 2018

1 reference

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Endothelin-1, endothelin-1 receptors and cardiac natriuretic peptides in failing human heart.

5 July 2018

1 reference

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Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation.

29 October 2018

1 reference

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Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing

29 October 2018

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12 December 2020

Trans -acting factors may cause dystrophin splicing misregulation in BMD skeletal muscles

1 reference

12 December 2020

Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure. Marked upregulation of genes encoding extracellular matrix components

1 reference

12 December 2020

Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy

1 reference

12 December 2020

10.1128/MCB.25.14.6267-6278.2005

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15988035%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

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13 January 2020

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