Innate immune defense against pneumococcal pneumonia requires pulmonary complement component C3. (Q33883472)

29 July 2017

Innate immune defense against pneumococcal pneumonia requires pulmonary complement component C3. (English)

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29 July 2017

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pneumococcal pneumonia

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Alison R Kerr

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29 July 2017

Gavin K Paterson

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2

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29 July 2017

Alan Riboldi-Tunnicliffe

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3

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29 July 2017

Tim J Mitchell

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4

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29 July 2017

language of work or name

English

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publication date

1 July 2005

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29 July 2017

Infection and Immunity

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29 July 2017

73

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29 July 2017

7

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29 July 2017

4245-4252

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Activation of the complement system generates antibacterial peptides

29 July 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Role of HtrA in the virulence and competence of Streptococcus pneumoniae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Murine complement interactions with Pseudomonas aeruginosa and their consequences during pneumonia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

ZmpB, a novel virulence factor of Streptococcus pneumoniae that induces tumor necrosis factor alpha production in the respiratory tract

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

The classical pathway is the dominant complement pathway required for innate immunity to Streptococcus pneumoniae infection in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Role of inflammatory mediators in resistance and susceptibility to pneumococcal infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Streptococcus pneumoniae causes experimental meningitis following intranasal and otitis media infections via a nonhematogenous route

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Recombinant PhpA protein, a unique histidine motif-containing protein from Streptococcus pneumoniae, protects mice against intranasal pneumococcal challenge

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Pneumolysin-induced complement depletion during experimental pneumococcal bacteremia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Role of Pneumolysin's complement-activating activity during pneumococcal bacteremia in cirrhotic rats.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Characterization of the galU gene of Streptococcus pneumoniae encoding a uridine diphosphoglucose pyrophosphorylase: a gene essential for capsular polysaccharide biosynthesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Cytokine kinetics and other host factors in response to pneumococcal pulmonary infection in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

The C5a chemoattractant receptor mediates mucosal defence to infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Activation of human complement by the pneumococcal toxin pneumolysin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Increased susceptibility to infection associated with abnormalities of complement-mediated functions and of the third component of complement (C3).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Pulmonary alveolar type II epithelial cells synthesize and secrete proteins of the classical and alternative complement pathways

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Infectious diseases associated with complement deficiencies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Recurrent septicemia associated with congenital deficiency of C2 and partial deficiency of factor B and the alternative complement pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

The effect of complement depletion on lung clearance of bacteria

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

The moribund state as an experimental endpoint.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Dual roles of PspC, a surface protein of Streptococcus pneumoniae, in binding human secretory IgA and factor H.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

PspC, a pneumococcal surface protein, binds human factor H.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Hic, a novel surface protein of Streptococcus pneumoniae that interferes with complement function.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Genetic disruption of the murine complement C3 promoter region generates deficient mice with extrahepatic expression of C3 mRNA.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1168602

Degradation of C3 by Streptococcus pneumoniae

29 October 2018

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12 December 2020

The critical role of complement in experimental pneumococcal sepsis

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12 December 2020

Protective role of complement in the development of experimental pneumococcal pneumonia in mice

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12 December 2020

A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis

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12 December 2020

The Role of C3 as an Opsonin in the Early Stages of Infection

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12 December 2020

Rapid isolation and characterization of native mouse complement components C3 and C5

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12 December 2020

Complement biosynthesis by human bronchoalveolar macrophages

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12 December 2020

Distinct roles for pneumolysin's cytotoxic and complement activities in the pathogenesis of pneumococcal pneumonia

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12 December 2020

MBL genotype and risk of invasive pneumococcal disease: a case-control study

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12 December 2020

The role of C5 in polymorphonuclear leukocyte recruitment in response to Streptococcus pneumoniae

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12 December 2020

10.1128/IAI.73.7.4245-4252.2005

Identifiers

DOI

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29 July 2017

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29 July 2017

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