Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers (Q33878699)

29 July 2017

Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers (English)

1 reference

29 July 2017

8

Valerie Daggett

1 reference

29 July 2017

7

Byron Caughey

1 reference

29 July 2017

Gene Hopping

1

1 reference

29 July 2017

Jackson Kellock

2

1 reference

29 July 2017

Ravi Pratap Barnwal

3

1 reference

29 July 2017

Peter Law

4

1 reference

29 July 2017

James Bryers

5

1 reference

29 July 2017

Gabriele Varani

6

1 reference

29 July 2017

language of work or name

English

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publication date

15 July 2014

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29 July 2017

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29 July 2017

3

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29 July 2017

e01681

1 reference

Designed Trpzip-3 β-Hairpin Inhibits Amyloid Formation in Two Different Amyloid Systems

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Structure-based discovery of fiber-binding compounds that reduce the cytotoxicity of amyloid beta

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

The amyloid state of proteins in human diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Microcin amyloid fibrils A are reservoir of toxic oligomeric species

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Dynameomics: a comprehensive database of protein dynamics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Fibril fragmentation enhances amyloid cytotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Experimental characterization of disordered and ordered aggregates populated during the process of amyloid fibril formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Amyloid formation by globular proteins under native conditions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

The intrinsic conformational propensities of the 20 naturally occurring amino acids and reflection of these propensities in proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Alpha-sheet: The toxic conformer in amyloid diseases?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Protein misfolding, functional amyloid, and human disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington's and Parkinson's diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

The pathway by which the tetrameric protein transthyretin dissociates.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Characterization of a possible amyloidogenic precursor in glutamine-repeat neurodegenerative diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

The most infectious prion protein particles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Pauling and Corey's alpha-pleated sheet structure may define the prefibrillar amyloidogenic intermediate in amyloid disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

The pleated sheet, a new layer configuration of polypeptide chains

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

What vibrations tell us about proteins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

A minimal peptide scaffold for beta-turn display: optimizing a strand position in disulfide-cyclized beta-hairpins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Tryptophan zippers: Stable, monomeric -hairpins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

A crystal structure with features of an antiparallel alpha-pleated sheet

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Two simple methods for quantifying low-affinity dye-substrate binding.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

On the helix sense of gramicidin A single channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

Anatomy of an amyloidogenic intermediate: conversion of beta-sheet to alpha-sheet structure in transthyretin at acidic pH.

5 July 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.01681

Methods for molecular dynamics simulations of protein folding/unfolding in solution.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.01681

Neurotoxic protein oligomers--what you see is not always what you get.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.01681

Structural basis for inhibiting β-amyloid oligomerization by a non-coded β-breaker-substituted endomorphin analogue.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.01681

Different disease-causing mutations in transthyretin trigger the same conformational conversion.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.01681

Amide I infrared spectral features characteristic of some untypical conformations appearing in the structures suggested for amyloids

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.01681

A peptide hairpin inhibitor of amyloid beta-protein oligomerization and fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.01681

The common architecture of cross-beta amyloid

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

29 October 2018

https://api.crossref.org/works/10.7554%2FELIFE.01681

The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.01681

Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.01681

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091096

29 October 2018

Identifiers

DOI

10.7554/ELIFE.01681

1 reference

29 July 2017

1 reference

29 July 2017

1 reference