Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza (Q33875118)

29 July 2017

Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza (English)

1 reference

29 July 2017

0 references

1 reference

3

Fernando A Bozza

1 reference

29 July 2017

Nyall R London

1

1 reference

29 July 2017

Weiquan Zhu

2

1 reference

29 July 2017

Matthew C P Smith

4

1 reference

29 July 2017

Daniel M Greif

5

1 reference

29 July 2017

Lise K Sorensen

6

1 reference

29 July 2017

Luming Chen

7

1 reference

29 July 2017

Yuuki Kaminoh

8

1 reference

29 July 2017

Aubrey C Chan

9

1 reference

29 July 2017

Samuel F Passi

10

1 reference

29 July 2017

Craig W Day

11

1 reference

29 July 2017

Dale L Barnard

12

1 reference

29 July 2017

Guy A Zimmerman

13

1 reference

29 July 2017

Mark A Krasnow

14

1 reference

29 July 2017

Dean Y Li

15

1 reference

29 July 2017

language of work or name

English

0 references

publication date

1 March 2010

1 reference

Science Translational Medicine

29 July 2017

1 reference

29 July 2017

2

1 reference

29 July 2017

23

1 reference

29 July 2017

23ra19

1 reference

Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Pandemic influenza: an inconvenient mutation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Cell adhesion dynamics at endothelial junctions: VE-cadherin as a major player

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Animal models of acute lung injury

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

The role of adherens junctions and VE-cadherin in the control of vascular permeability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

The branching programme of mouse lung development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Slits and their receptors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Dengue and hemorrhagic fever: a potential threat to public health in the United States

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Bioterrorism: management of major biological agents

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

TNF-alpha increases tyrosine phosphorylation of vascular endothelial cadherin and opens the paracellular pathway through fyn activation in human lung endothelia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Interaction of the guidance molecule Slit with cellular receptors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Influenza pandemics: past, present and future.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Public health risk from avian influenza viruses.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Interleukin-1beta reduces transcellular monocyte diapedesis and compromises endothelial adherens junction integrity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Cerebral malaria -- a neurovascular pathology with many riddles still to be solved.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Infections associated with tumor necrosis factor-alpha antagonists

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

In vitro and in vivo influenza virus-inhibitory effects of viramidine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Magic roundabout, a tumor endothelial marker: expression and signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Robo4 is a vascular-specific receptor that inhibits endothelial migration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Toll-like receptors and their role in experimental models of microbial infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Points of control in inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Monoclonal antibodies directed to different regions of vascular endothelial cadherin extracellular domain affect adhesion and clustering of the protein and modulate endothelial permeability

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Influenza virus: a master of metamorphosis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

The acute respiratory distress syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Proinflammatory and anti-inflammatory cytokines as mediators in the pathogenesis of septic shock

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Pattern of cytokines and pharmacomodulation in sepsis induced by cecal ligation and puncture compared with that induced by endotoxin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Mutations affecting growth cone guidance in Drosophila: genes necessary for guidance toward or away from the midline

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

Public health. Next flu pandemic: what to do until the vaccine arrives?

28 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Innate immune activation as a broad-spectrum biodefense strategy Prospects and research challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal state

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Update on avian influenza A (H5N1) virus infection in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Forever unprepared--the predictable unpredictability of pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Endogenous endothelial cell signaling systems maintain vascular stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

INCREASED SUSCEPTIBILITY TO SEPTIC AND ENDOTOXIC SHOCK IN MONOCYTE CHEMOATTRACTANT PROTEIN 1/CC CHEMOKINE LIGAND 2-DEFICIENT MICE CORRELATES WITH REDUCED INTERLEUKIN 10 AND ENHANCED MACROPHAGE MIGRATION INHIBITORY FACTOR PRODUCTION

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Re-evaluation of Evans Blue dye as a marker of albumin clearance in murine models of acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signaling

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2875996

VEGF regulates the mobilization of VEGFR2/KDR from an intracellular endothelial storage compartment

29 October 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3000678

Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20375003

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20375003

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cecal ligation and puncture

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20375003

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.3000678

1 reference

29 July 2017

1 reference

29 July 2017

1 reference