Blockade of GABA(B) receptors completely reverses age-related learning impairment. (Q33870626)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19723562%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Blockade of GABA(B) receptors completely reverses age-related learning impairment (English)

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6 February 2020

1

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6 February 2020

author name string

C Bañuelos

series ordinal

2

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6 February 2020

J D Mayse

series ordinal

3

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6 February 2020

J L Bizon

series ordinal

4

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6 February 2020

language of work or name

English

0 references

publication date

31 August 2009

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6 February 2020

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6 February 2020

volume

164

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6 February 2020

issue

3

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6 February 2020

page(s)

941-947

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Drug development for Alzheimer's disease: where are we now and where are we headed?

6 February 2020

cites work

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Cognitive aging: a common decline of episodic recollection and spatial memory in rats

5 July 2018

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Cholinesterase inhibitors in mild cognitive impairment: a systematic review of randomised trials

5 July 2018

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Spatial reference and working memory across the lifespan of male Fischer 344 rats

5 July 2018

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GABA(B) receptors: structure and function

5 July 2018

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Rats depend on habit memory for discrimination learning and retention

5 July 2018

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Role of cholinesterase inhibitors in dementia care needs rethinking

5 July 2018

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Odor identification and decline in different cognitive domains in old age.

5 July 2018

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5 July 2018

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Vitamin E and donepezil for the treatment of mild cognitive impairment

5 July 2018

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SGS742: the first GABA(B) receptor antagonist in clinical trials

5 July 2018

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Molecular structure and physiological functions of GABA(B) receptors

5 July 2018

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Septohippocampal acetylcholine: involved in but not necessary for learning and memory?

5 July 2018

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Treatment of dementia with neurotransmission modulation

5 July 2018

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Have cholinergic therapies reached their clinical boundary in Alzheimer's disease?

5 July 2018

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Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins

5 July 2018

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Recent trends in disability and functioning among older adults in the United States: a systematic review

5 July 2018

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GABA(B) receptors couple directly to the transcription factor ATF4.

5 July 2018

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The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx

5 July 2018

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Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease

5 July 2018

1 reference

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Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function

5 July 2018

1 reference

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Memory systems analyses of mnemonic disorders in aging and age-related diseases

5 July 2018

1 reference

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Intact spatial learning following lesions of basal forebrain cholinergic neurons.

5 July 2018

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Antagonism of baclofen-induced depression of whole-cell synaptic currents in spinal dorsal horn neurones by the potent GABAB antagonist CGP55845.

5 July 2018

1 reference

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Cholinergic and GABAergic neurons in the nucleus basalis region of young and aged rats.

5 July 2018

1 reference

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Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists

5 July 2018

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Hippocampal system dysfunction and odor discrimination learning in rats: Impairment of facilitation depending on representational demands

5 July 2018

1 reference

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GABA-containing neurons in the septum control inhibitory interneurons in the hippocampus.

5 July 2018

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Further studies of hippocampal representation during odor discrimination learning.

5 July 2018

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The cholinergic innervation of the rat fascia dentata: identification of target structures on granule cells by combining choline acetyltransferase immunocytochemistry and Golgi impregnation

5 July 2018

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Hippocampal levels of phosphorylated protein kinase A (phosphor-S96) are linked to spatial memory enhancement by SGS742.

5 July 2018

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Deficits across multiple cognitive domains in a subset of aged Fischer 344 rats.

29 October 2018

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GABAB receptor antagonism abolishes the learning impairments in rats with chronic atypical absence seizures.

29 October 2018

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Inhibition of hippocampal function in mild cognitive impairment: targeting the cholinergic hypothesis

29 October 2018

1 reference

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Olfactory screening test in mild cognitive impairment.

29 October 2018

1 reference

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Mild cognitive impairment and preclinical Alzheimer's disease.

29 October 2018

1 reference

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GABAB receptor antagonist SGS742 improves spatial memory and reduces protein binding to the cAMP response element (CRE) in the hippocampus

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

Involvement of GABAergic and cholinergic medial septal neurons in hippocampal theta rhythm.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

Effects of ethanol and GABAB drugs on working memory in C57BL/6J and DBA/2J mice

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

Preserved anterograde and retrograde memory of rapidly acquired olfactory discrminations after neurotoxic hippocampal lesions.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

Risk factors for mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 2.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

Degenerative Changes in Forebrain Cholinergic Nuclei Correlate with Cognitive Impairments in Aged Rats.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

GABAergic septohippocampal neurons are not necessary for spatial memory.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

Effects of high-affinity GABAB receptor antagonists on active and passive avoidance responding in rodents with gamma-hydroxybutyrolactone-induced absence syndrome

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

Interactions between 192-IgG saporin and intraseptal cholinergic and GABAergic drugs: role of cholinergic medial septal neurons in spatial working memory.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874897

29 October 2018

1 reference

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The modulatory effects of high affinity GABA(B) receptor antagonists in an active avoidance learning paradigm in rats.

29 October 2018

1 reference

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CGP 36,742, an orally active GABAB receptor antagonist, facilitates memory in a social recognition test in rats.

29 October 2018

1 reference

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The GABAB receptor antagonist CGP 36,742 and the nootropic oxiracetam facilitate the formation of long-term memory.

29 October 2018

1 reference

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Selective immunotoxic lesions of basal forebrain cholinergic cells: effects on learning and memory in rats

29 October 2018

1 reference

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10.1016/J.NEUROSCIENCE.2009.08.055

29 October 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19723562%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19723562%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

19723562

1 reference