Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes (Q33870085)

29 July 2017

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Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes (English)

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29 July 2017

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10

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29 July 2017

21

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Srdjan Djurovic

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Thomas Werge

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Thomas Werge

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29 July 2017

Piotr Dworzynski

5

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Irene Kouskoumvekaki

Irene Kouskoumvekaki

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Martin L Miller

Martin Lee Miller

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Manuel A Ferreira

Manuel A Ferreira

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Christopher T. Workman

Christopher T Workman

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Ole Mors

Ole Mors

20

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Torben Hansen

Torben Hansen

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Ingrid Melle

12

Ingrid Melle

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ORCID Public Data File 2021

29 July 2017

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Anders D. Børglum

13

Anders D Børglum

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29 July 2017

3

Kasper Lage

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29 July 2017

Niclas Tue Hansen

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29 July 2017

Pernille Koefoed

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29 July 2017

Tracey J Flint

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29 July 2017

Erling Mellerup

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29 July 2017

Henrik Dam

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29 July 2017

Shaun Purcell

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11 April 2011

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35

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29 July 2017

318-332

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SUSPECTS: enabling fast and effective prioritization of positional candidates

29 July 2017

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https://api.crossref.org/works/10.1002%2FGEPI.20580

Gene prioritization through genomic data fusion

21 January 2018

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https://api.crossref.org/works/10.1002%2FGEPI.20580

Prediction of human disease genes by human-mouse conserved coexpression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Schizophrenia: from genes to phenes to disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

BIND--The Biomolecular Interaction Network Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

PDZBase: a protein-protein interaction database for PDZ-domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Systematic identification of human mitochondrial disease genes through integrative genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

DOMINO: a database of domain-peptide interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

MINT: the Molecular INTeraction database

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Integration of biological networks and gene expression data using Cytoscape

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Genome-wide association. Closing the net on common disease genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

The emerging genetic architecture of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Using genome-wide pathway analysis to unravel the etiology of complex diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Using biological networks to search for interacting loci in genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Using protein complexes to predict phenotypic effects of gene mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A new measure of the effective number of tests, a practical tool for comparing families of non-independent significance tests

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A computational system to select candidate genes for complex human traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Proteome survey reveals modularity of the yeast cell machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Analysis of protein sequence and interaction data for candidate disease gene prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Integrating genetic and network analysis to characterize genes related to mouse weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A protein interaction map of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Family-based association of YWHAH in psychotic bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

MPact: the MIPS protein interaction resource on yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

GSEA-SNP: applying gene set enrichment analysis to SNP data from genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Using literature-based discovery to identify disease candidate genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

CANDID: a flexible method for prioritizing candidate genes for complex human traits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Identification of the site of interaction of the 14-3-3 protein with phosphorylated tryptophan hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Protein networks in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

KEGG for linking genomes to life and the environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Gene expression profiling in postmortem prefrontal cortex of major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

IntAct--open source resource for molecular interaction data

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Role of 14-3-3 eta as a positive regulator of the glucocorticoid receptor transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Walking the interactome for prioritization of candidate disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Most rare missense alleles are deleterious in humans: implications for complex disease and association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A human phenome-interactome network of protein complexes implicated in genetic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Hundreds of variants clustered in genomic loci and biological pathways affect human height

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A genomic pathway approach to a complex disease: axon guidance and Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Identification of ten loci associated with height highlights new biological pathways in human growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A map of the interactome network of the metazoan C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Agreement among type 2 diabetes linkage studies but a poor correlation with results from genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Genome-wide identification of genes likely to be involved in human genetic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

The involvement of GSK3beta in bipolar disorder: integrating evidence from multiple types of genetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

CGI: a new approach for prioritizing genes by combining gene expression and protein-protein interaction data

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Personal genomes: The case of the missing heritability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Gene set-based analysis of polymorphisms: finding pathways or biological processes associated to traits in genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

MIPS: analysis and annotation of proteins from whole genomes in 2005.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Network-based model weighting to detect multiple loci influencing complex diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

G2D: a tool for mining genes associated with disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Development of human protein reference database as an initial platform for approaching systems biology in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Are rare variants responsible for susceptibility to complex diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Insulin signaling regulating genes: effect on T2DM and cardiovascular risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Network modeling links breast cancer susceptibility and centrosome dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

New perspectives for the elucidation of genetic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

TOM: a web-based integrated approach for identification of candidate disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

CORUM: the comprehensive resource of mammalian protein complexes--2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Gene expression analysis of bipolar disorder reveals downregulation of the ubiquitin cycle and alterations in synaptic genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

The Database of Interacting Proteins: 2004 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

LDL-cholesterol concentrations: a genome-wide association study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Tryptophan hydroxylase gene and major psychoses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Gene prioritization in Type 2 Diabetes using domain interactions and network analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Whole-genome association study of bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

BioGRID: a general repository for interaction datasets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Biological, clinical and population relevance of 95 loci for blood lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Integration of text- and data-mining using ontologies successfully selects disease gene candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Pathway analysis of seven common diseases assessed by genome-wide association

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

POCUS: mining genomic sequence annotation to predict disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

GeneSeeker: extraction and integration of human disease-related information from web-based genetic databases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Interaction of the ligand-activated glucocorticoid receptor with the 14-3-3 eta protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Pathway-based approaches for analysis of genomewide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

The Pathway Less Traveled: Moving from Candidate Genes to Candidate Pathways in the Analysis of Genome-Wide Data from Large Scale Pharmacogenetic Association Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

The genomic landscapes of human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Network-based global inference of human disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Discovering disease-genes by topological features in human protein-protein interaction network.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Gene prioritization and clustering by multi-view text mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

A navigator for human genome epidemiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Path: a tool to facilitate pathway-based genetic association analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

The SNP ratio test: pathway analysis of genome-wide association datasets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

INTERSNP: genome-wide interaction analysis guided by a priori information

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

Guilt beyond a reasonable doubt

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

7 January 2021

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

7 January 2021

Problems with Genome-Wide Association Studies

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

7 January 2021

Altered glucocorticoid receptor signaling cascade in lymphocytes of bipolar disorder patients

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

7 January 2021

A text-mining analysis of the human phenome

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

7 January 2021

Associating genes and protein complexes with disease via network propagation

1 reference

https://api.crossref.org/works/10.1002%2FGEPI.20580

7 January 2021

Identifiers

DOI

10.1002/GEPI.20580

1 reference

29 July 2017

1 reference