Molecular pathology of prostate cancer revealed by next-generation sequencing: opportunities for genome-based personalized therapy (Q33862462)

29 July 2017

Molecular pathology of prostate cancer revealed by next-generation sequencing: opportunities for genome-based personalized therapy (English)

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29 July 2017

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1

Jiaoti Huang

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29 July 2017

Jason K Wang

2

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PubMed ID

23385974

29 July 2017

Yin Sun

series ordinal

3

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29 July 2017

1 May 2013

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Current Opinion in Urology

29 July 2017

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29 July 2017

23

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3

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29 July 2017

189-193

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PubMed ID

23385974

describes a project that uses

29 July 2017

massive parallel sequencing

1 reference

based on heuristic

inferred from title

cites work

Targeted next-generation sequencing of advanced prostate cancer identifies potential therapeutic targets and disease heterogeneity

1 reference

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B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer

5 July 2018

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KLF6 loss of function in human prostate cancer progression is implicated in resistance to androgen deprivation.

5 July 2018

1 reference

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Slug, a unique androgen-regulated transcription factor, coordinates androgen receptor to facilitate castration resistance in prostate cancer

5 July 2018

1 reference

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The mutational landscape of lethal castration-resistant prostate cancer

5 July 2018

1 reference

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Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

5 July 2018

1 reference

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From sequence to molecular pathology, and a mechanism driving the neuroendocrine phenotype in prostate cancer

5 July 2018

1 reference

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Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets

5 July 2018

1 reference

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Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway

5 July 2018

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Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells

5 July 2018

1 reference

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Novel membrane-associated androgen receptor splice variant potentiates proliferative and survival responses in prostate cancer cells.

5 July 2018

1 reference

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Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

5 July 2018

1 reference

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Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

5 July 2018

1 reference

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A novel nuclear role for the Vav3 nucleotide exchange factor in androgen receptor coactivation in prostate cancer

5 July 2018

1 reference

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Integrated genomic analyses of ovarian carcinoma

5 July 2018

1 reference

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Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth

5 July 2018

1 reference

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Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

The genomic complexity of primary human prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

Amplification and overexpression of vinculin are associated with increased tumour cell proliferation and progression in advanced prostate cancer

5 July 2018

1 reference

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The genetic landscape of the childhood cancer medulloblastoma

5 July 2018

1 reference

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CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

Neuroendocrine differentiation in prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

Human mutation rate associated with DNA replication timing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

Immunohistochemical characterization of neuroendocrine cells in prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

Identification of the MLL2 complex as a coactivator for estrogen receptor alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

Differential expression of interleukin-8 and its receptors in the neuroendocrine and non-neuroendocrine compartments of prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4086526

10.1097/MOU.0B013E32835E9EF4

5 July 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference

29 July 2017

1 reference

PubMed ID

23385974