Modulation of silent and constitutively active nociceptin/orphanin FQ receptors by potent receptor antagonists and Na+ ions in rat sympathetic neurons (Q33862053)

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English	Modulation of silent and constitutively active nociceptin/orphanin FQ receptors by potent receptor antagonists and Na+ ions in rat sympathetic neurons	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

Modulation of silent and constitutively active nociceptin/orphanin FQ receptors by potent receptor antagonists and Na+ ions in rat sympathetic neurons (English)

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Europe PubMed Central

29 July 2017

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author name string

Saifeldin Mahmoud

1

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Europe PubMed Central

29 July 2017

Wojciech Margas

2

1 reference

Europe PubMed Central

29 July 2017

Claudio Trapella

3

1 reference

Europe PubMed Central

29 July 2017

Girolamo Caló

4

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Europe PubMed Central

29 July 2017

Victor Ruiz-Velasco

5

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Europe PubMed Central

29 July 2017

language of work or name

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publication date

16 February 2010

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29 July 2017

Molecular Pharmacology

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Europe PubMed Central

29 July 2017

77

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Europe PubMed Central

29 July 2017

5

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29 July 2017

804-817

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Europe PubMed Central

29 July 2017

The nociceptin/orphanin FQ receptor: a target with broad therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Coupling specificity of NOP opioid receptors to pertussis-toxin-sensitive Galpha proteins in adult rat stellate ganglion neurons using small interference RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Allosteric modulation of heterodimeric G-protein-coupled receptors.

1 reference

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5 July 2018

Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarity

1 reference

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5 July 2018

Small-molecule agonists and antagonists of the opioid receptor-like receptor (ORL1, NOP): ligand-based analysis of structural factors influencing intrinsic activity at NOP

1 reference

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5 July 2018

UFP-101, a peptide antagonist selective for the nociceptin/orphanin FQ receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Modulation of Ca2+ channels by opioid receptor-like 1 receptors natively expressed in rat stellate ganglion neurons innervating cardiac muscle

1 reference

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5 July 2018

Partial agonist behaviour depends upon the level of nociceptin/orphanin FQ receptor expression: studies using the ecdysone-inducible mammalian expression system.

1 reference

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5 July 2018

Pharmacological profiles of presynaptic nociceptin/orphanin FQ receptors modulating 5-hydroxytryptamine and noradrenaline release in the rat neocortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Mechanisms of inverse agonism at G-protein-coupled receptors

1 reference

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5 July 2018

The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

4-Aminoquinolines: novel nociceptin antagonists with analgesic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Orphanin FQ/nociceptin receptor binding studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Interaction of [3H]orphanin FQ and 125I-Tyr14-orphanin FQ with the orphanin FQ receptor: kinetics and modulation by cations and guanine nucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Calcium-activated chloride current in normal mouse sympathetic ganglion cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins

1 reference

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5 July 2018

Spontaneous association between opioid receptors and GTP-binding regulatory proteins in native membranes: specific regulation by antagonists and sodium ions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

5 July 2018

Structure-activity studies on the nociceptin/orphanin FQ receptor antagonist 1-benzyl-N-{3-[spiroisobenzofuran-1(3H),4'-piperidin-1-yl]propyl} pyrrolidine-2-carboxamide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Effects of receptor density on Nociceptin/OrphaninFQ peptide receptor desensitisation: studies using the ecdysone inducible expression system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Expression of G-protein signaling components in adult mammalian neurons by microinjection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

A novel approach employing ultrasound guidance for percutaneous cardiac muscle injection to retrograde label rat stellate ganglion neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Morphine and endomorphin-1 differently influence pronociceptin/orphanin FQ system in neuropathic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Agonist-independent modulation of N-type calcium channels by ORL1 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Sodium ions and GTP decrease the potency of [Nphe1]N/OFQ(1-13)NH2 in blocking nociceptin/orphanin FQ receptors coupled to cyclic AMP in N1E-115 neuroblastoma cells and rat olfactory bulb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Up-regulation of ORL-1 receptors in spinal tissue of allodynic rats after sciatic nerve injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Nociceptin/orphanin FQ binding increases in superficial laminae of the rat spinal cord during persistent peripheral inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872970

29 October 2018

Quantitative analysis of nociceptin in blood of patients with acute and chronic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20159949

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin/orphanin FQ and its receptor--potential targets for pain therapy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20159949

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double-pulse calcium channel current facilitation in adult rat sympathetic neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/20159949

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anomalous permeation of Na+ through a putative K+ channel in rat superior cervical ganglion neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/20159949

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin gene expression in rat dorsal root ganglia induced by peripheral inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20159949

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/MOL.109.062208

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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