Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours (Q33861833)

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English	Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

Ex vivo expanded natural killer cells from breast cancer patients and healthy donors are highly cytotoxic against breast cancer cell lines and patient-derived tumours (English)

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29 July 2017

13

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2 June 2020

author name string

Mira M Shenouda

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2 June 2020

Amy Gillgrass

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2 June 2020

Tina Nham

3

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2 June 2020

Richard Hogg

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2 June 2020

Amanda J Lee

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2 June 2020

Marianne V Chew

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2 June 2020

Mahsa Shafaei

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2 June 2020

Craig Aarts

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2 June 2020

Dean A Lee

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2 June 2020

John Hassell

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2 June 2020

Anita Bane

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2 June 2020

Sukhbinder Dhesy-Thind

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publication date

1 July 2017

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29 July 2017

Breast Cancer Research

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2 June 2020

19

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2 June 2020

76

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2 June 2020

1

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2 June 2020

https://scigraph.springernature.com/pub.10.1186/s13058-017-0867-9

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Tumor-infiltrating lymphocytes and breast cancer: Beyond the prognostic and predictive utility.

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PD1 blockade enhances cytotoxicity of in vitro expanded natural killer cells towards myeloma cells

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Phase I clinical trial of autologous NK cell therapy using novel expansion method in patients with advanced digestive cancer

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"Adherent" versus Other Isolation Strategies for Expanding Purified, Potent, and Activated Human NK Cells for Cancer Immunotherapy

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Highly effective NK cells are associated with good prognosis in patients with metastatic prostate cancer

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CD160 is essential for NK-mediated IFN-γ production

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5 July 2018

HER2-family signalling mechanisms, clinical implications and targeting in breast cancer

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5 July 2018

Ex vivo-expanded natural killer cells demonstrate robust proliferation in vivo in high-risk relapsed multiple myeloma patients

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5 July 2018

Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer

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5 July 2018

Clinical utility of natural killer cells in cancer therapy and transplantation

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5 July 2018

Synergistic enhancement of NK cell-mediated cytotoxicity by combination of histone deacetylase inhibitor and ionizing radiation

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The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity.

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5 July 2018

Theranostic and molecular classification of breast cancer

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5 July 2018

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5 July 2018

Biological subtypes of breast cancer: current concepts and implications for recurrence patterns

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5 July 2018

Advantages and clinical applications of natural killer cells in cancer immunotherapy

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5 July 2018

Molecular signatures mostly associated with NK cells are predictive of relapse free survival in breast cancer patients.

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5 July 2018

Intratumor hypoxia promotes immune tolerance by inducing regulatory T cells via TGF-β1 in gastric cancer

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5 July 2018

NK cell-based immunotherapy for malignant diseases

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5 July 2018

Ex vivo expansion of highly cytotoxic human NK cells by cocultivation with irradiated tumor cells for adoptive immunotherapy

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5 July 2018

Membrane-bound interleukin-21 and CD137 ligand induce functional human natural killer cells from peripheral blood mononuclear cells through STAT-3 activation

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5 July 2018

Molecular Mechanisms of Trastuzumab-Based Treatment in HER2-Overexpressing Breast Cancer

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5 July 2018

Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells

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5 July 2018

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells

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5 July 2018

Hypoxia induces escape from innate immunity in cancer cells via increased expression of ADAM10: role of nitric oxide

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5 July 2018

Adoptive transfer of autologous natural killer cells leads to high levels of circulating natural killer cells but does not mediate tumor regression

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5 July 2018

Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

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5 July 2018

Stimulating natural killer cells to protect against cancer: recent developments.

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5 July 2018

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5 July 2018

Eradication of B-lineage cells and regression of lymphoma in a patient treated with autologous T cells genetically engineered to recognize CD19.

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Good manufacturing practice-compliant cell sorting and large-scale expansion of single KIR-positive alloreactive human natural killer cells for multiple infusions to leukemia patients

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5 July 2018

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5 July 2018

Differential mechanisms of shedding of the glycosylphosphatidylinositol (GPI)-anchored NKG2D ligands

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Expansion of highly cytotoxic human natural killer cells for cancer cell therapy

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Clinical-grade ex vivo-expanded human natural killer cells up-regulate activating receptors and death receptor ligands and have enhanced cytolytic activity against tumor cells

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5 July 2018

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy

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5 July 2018

NK cells and cancer.

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5 July 2018

Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism?

1 reference

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5 July 2018

IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients

1 reference

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5 July 2018

Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells

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5 July 2018

Autologous natural killer cell therapy for human recurrent malignant glioma.

1 reference

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5 July 2018

Reconstruction of functionally normal and malignant human breast tissues in mice

1 reference

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5 July 2018

Large-scale generation of natural killer lymphocytes for clinical application

1 reference

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5 July 2018

Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia

1 reference

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5 July 2018

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

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5 July 2018

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5 July 2018

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5 July 2018

Ex vivo expansion of natural killer cells for clinical applications.

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21 January 2018

A phase I trial of adoptive transfer of allogeneic natural killer cells in patients with advanced non-small cell lung cancer

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21 January 2018

Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation.

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21 January 2018

Induction of NK cell activity against fresh human leukemia in culture with interleukin 2

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12 December 2020

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A new method for in vitro expansion of cytotoxic human CD3-CD56+ natural killer cells

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https://pubmed.ncbi.nlm.nih.gov/28668076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28668076

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capillary leak syndrome associated with elevated IL-2 serum levels after allogeneic bone marrow transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/28668076

12 December 2020

based on heuristic

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Analysis of the costimulatory role of IL-2 and IL-15 in initiating proliferation of resting (CD56dim) human NK cells

1 reference

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12 December 2020

based on heuristic

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In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13058-017-0867-9

1 reference

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2 June 2020

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2 June 2020

1 reference

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2 June 2020

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