A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease. (Q33855619)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease (English)

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9 March 2020

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Doris Lambracht-Washington

1

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9 March 2020

Larry D Anderson

4

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9 March 2020

Todd Eagar

5

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9 March 2020

author name string

Bao-xi Qu

2

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9 March 2020

Min Fu

3

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9 March 2020

Roger N Rosenberg

7

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9 March 2020

Olaf Stüve

6

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9 March 2020

publication date

1 October 2012

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Journal of Neuroimmunology

9 March 2020

published in

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9 March 2020

volume

254

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9 March 2020

issue

1-2

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9 March 2020

page(s)

63-68

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DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation

9 March 2020

cites work

1 reference

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Analysis of three plasmid systems for use in DNA A beta 42 immunization as therapy for Alzheimer's disease

5 July 2018

1 reference

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Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology

5 July 2018

1 reference

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Can Alzheimer disease be prevented by amyloid-beta immunotherapy?

5 July 2018

1 reference

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DNA prime-protein boost increased the titer, avidity and persistence of anti-Abeta antibodies in wild-type mice.

5 July 2018

1 reference

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DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.

5 July 2018

1 reference

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Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

5 July 2018

1 reference

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Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy

5 July 2018

1 reference

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Enhancing Th2 immune responses against amyloid protein by a DNA prime-adenovirus boost regimen for Alzheimer's disease

5 July 2018

1 reference

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Abeta42 gene vaccine prevents Abeta42 deposition in brain of double transgenic mice.

5 July 2018

1 reference

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Abeta42 gene vaccination reduces brain amyloid plaque burden in transgenic mice.

5 July 2018

1 reference

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Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

5 July 2018

1 reference

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Gene vaccination to bias the immune response to amyloid-beta peptide as therapy for Alzheimer disease

5 July 2018

1 reference

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Jump-starting the immune system: prime-boosting comes of age.

5 July 2018

1 reference

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Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology

5 July 2018

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

5 July 2018

1 reference

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A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

5 July 2018

1 reference

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

5 July 2018

1 reference

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New insights into the genetics of Alzheimer's disease

5 July 2018

1 reference

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Amyloid beta-protein and the genetics of Alzheimer's disease

5 July 2018

1 reference

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

5 July 2018

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Neutralization of soluble, synaptotoxic amyloid β species by antibodies is epitope specific.

5 July 2018

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Reduced oligomeric and vascular amyloid-beta following immunization of TgCRND8 mice with an Alzheimer's DNA vaccine.

29 October 2018

1 reference

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Enhanced Th2 immunity after DNA prime-protein boost immunization with amyloid beta (1-42) plus CpG oligodeoxynucleotides in aged rats.

29 October 2018

1 reference

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Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease.

29 October 2018

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Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease.

29 October 2018

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Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

29 October 2018

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A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

29 October 2018

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Th1 and Th2 CD4+ T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivo

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23036592

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JNEUROIM.2012.09.008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference