Identification of multiple rate-limiting steps during the human mitochondrial transcription cycle in vitro (Q33855344)

29 July 2017

Identification of multiple rate-limiting steps during the human mitochondrial transcription cycle in vitro (English)

1 reference

29 July 2017

6

Craig E Cameron

1 reference

29 July 2017

Maria F Lodeiro

1

1 reference

29 July 2017

Akira U Uchida

2

1 reference

29 July 2017

Jamie J Arnold

3

1 reference

29 July 2017

Shelley L Reynolds

4

1 reference

29 July 2017

Ibrahim M Moustafa

5

1 reference

29 July 2017

language of work or name

English

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publication date

29 March 2010

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29 July 2017

16

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Journal of Biological Chemistry

inferred from page(s)

published in

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29 July 2017

285

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29 July 2017

16387-16402

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29 July 2017

21

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describes a project that uses

29 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2871506/fullTextXML

inferred from PubMed Central ID database lookup

cites work

TFB2 is a transient component of the catalytic site of the human mitochondrial RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Defining mechanisms that regulate RNA polymerase II transcription in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Divergent transcription: a new feature of active promoters

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Direct detection of abortive RNA transcripts in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Mechanism of sequence-specific pausing of bacterial RNA polymerase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

A promoter recognition mechanism common to yeast mitochondrial and phage t7 RNA polymerases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Structural analysis and DNA binding of the HMG domains of the human mitochondrial transcription factor A

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Fluorescence mapping of the open complex of yeast mitochondrial RNA polymerase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Promoter proximal pausing on genes in metazoans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Poised polymerases: on your mark...get set...go!

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Mitochondrial disorders in the nervous system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Mitochondrial transcription factor B2 is essential for metabolic function in Drosophila melanogaster development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

The transition from transcriptional initiation to elongation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Mitochondrial mutations: genotype to phenotype.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Inherited mitochondrial diseases of DNA replication

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Why do we still have a maternally inherited mitochondrial DNA? Insights from evolutionary medicine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

DNA replication and transcription in mammalian mitochondria

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Mitochondrial transcription and its regulation in mammalian cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Initiation and beyond: multiple functions of the human mitochondrial transcription machinery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

The regulatory roles and mechanism of transcriptional pausing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

The effects of upstream DNA on open complex formation by Escherichia coli RNA polymerase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

The mitochondrial RNA polymerase contributes critically to promoter specificity in mammalian cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Coupling the mitochondrial transcription machinery to human disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Drosophila mitochondrial transcription factor B2 regulates mitochondrial DNA copy number and transcription in schneider cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Human mitochondrial transcription factor B1 interacts with the C-terminal activation region of h-mtTFA and stimulates transcription independently of its RNA methyltransferase activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Bacterial RNA polymerases: the wholo story

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Replication and transcription of mammalian mitochondrial DNA.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Binding of the priming nucleotide in the initiation of transcription by T7 RNA polymerase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

HMG1 and 2, and related 'architectural' DNA-binding proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Nam1p, a protein involved in RNA processing and translation, is coupled to transcription through an interaction with yeast mitochondrial RNA polymerase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Transcription and replication of mitochondrial DNA.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Studies of contacts between T7 RNA polymerase and its promoter reveal features in common with multisubunit RNA polymerases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Basic mechanisms of transcript elongation and its regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Analysis of open complex formation during RNA polymerase II transcription initiation using heteroduplex templates and potassium permanganate probing

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Abortive cycling and the release of polymerase for elongation at the sigma 54-dependent glnAp2 promoter.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Promoter selection in human mitochondria involves binding of a transcription factor to orientation-independent upstream regulatory elements

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Processivity in early stages of transcription by T7 RNA polymerase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

T7 RNA polymerase does not interact with the 5'-phosphate of the initiating nucleotide.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Flexible recognition of rapidly evolving promoter sequences by mitochondrial transcription factor 1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Markedly different ATP requirements for rRNA synthesis and mtDNA light strand transcription versus mRNA synthesis in isolated human mitochondria.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

Functional Transcription Elongation Complexes from Synthetic RNA-DNA Bubble Duplexes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871506

DNA polymerase gamma and mitochondrial disease: understanding the consequence of POLG mutations.

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Molecular genetic aspects of human mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Mitochondrial transcription factor A regulates mtDNA copy number in mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

A human mitochondrial transcription factor is related to RNA adenine methyltransferases and binds S-adenosylmethionine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Drosophila mitochondrial transcription factor B1 modulates mitochondrial translation but not transcription or DNA copy number in Schneider cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Addition of a 29 residue carboxyl-terminal tail converts a simple HMG box-containing protein into a transcriptional activator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Purification and characterization of human mitochondrial transcription factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Kinetic analysis of T7 RNA polymerase-promoter interactions with small synthetic promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Kinetic and thermodynamic basis of promoter strength: multiple steps of transcription initiation by T7 RNA polymerase are modulated by the promoter sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Mechanism of instability in abortive cycling by T7 RNA polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

In vitro studies of transcript initiation by Escherichia coli RNA polymerase. 1. RNA chain initiation, abortive initiation, and promoter escape at three bacteriophage promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

The energetics of consensus promoter opening by T7 RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Allosteric control of Escherichia coli rRNA promoter complexes by DksA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

RNA polymerase active center: the molecular engine of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Urinary oestrogen patterns in long follicular phases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.092676

Conserved sequence box II directs transcription termination and primer formation in mitochondria

21 January 2018

1 reference

12 December 2020

Sensitivity of the yeast mitochondrial RNA polymerase to +1 and +2 initiating nucleotides

1 reference

12 December 2020

Role of open complex instability in kinetic promoter selection by bacteriophage T7 RNA polymerase

1 reference

12 December 2020

Poliovirus RNA-dependent RNA polymerase (3Dpol) is sufficient for template switching in vitro

1 reference

12 December 2020

Single-nucleotide resolution of RNA strands in the presence of their RNA complements

1 reference

12 December 2020

Termination factor-mediated DNA loop between termination and initiation sites drives mitochondrial rRNA synthesis

1 reference

12 December 2020

Mitochondrial transcription is regulated via an ATP "sensing" mechanism that couples RNA abundance to respiration

1 reference

12 December 2020

Hierarchy of base-pair preference in the binding domain of the bacteriophage T7 promoter

1 reference

12 December 2020

Termination and slippage by bacteriophage T7 RNA polymerase

1 reference

12 December 2020

Equilibrium and stopped-flow kinetic studies of interaction between T7 RNA polymerase and its promoters measured by protein and 2-aminopurine fluorescence changes

1 reference

12 December 2020

Roles for a promoter and RNA processing in the synthesis of mitochondrial displacement-loop strands

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.092676

1 reference

29 July 2017

1 reference

29 July 2017

1 reference