Opiate modulating properties of nociceptin/orphanin FQ. (Q33855336)

29 July 2017

1 reference

title

Opiate modulating properties of nociceptin/orphanin FQ. (English)

1 reference

29 July 2017

0 references

L M Harrison

1

1 reference

PubMed ID

10704732

29 July 2017

D K Grandy

series ordinal

2

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29 July 2017

1 January 2000

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29 July 2017

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29 July 2017

21

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29 July 2017

1

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29 July 2017

151-172

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Nociceptin inhibits T-type Ca2+ channel current in rat sensory neurons by a G-protein-independent mechanism

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Axotomy reduces the effect of analgesic opioids yet increases the effect of nociceptin on dorsal root ganglion neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Endogenous opioids: overview and current issues

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Endogenous Opioids: Biology and Function

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin/orphanin FQ increases blood pressure and heart rate via sympathetic activation in sheep

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Signal transduction via the MAP kinases: proceed at your own RSK.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ stimulates prolactin and growth hormone release in male and female rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin, an endogenous ligand for the ORL1 receptor, has novel hypotensive activity in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

[Tyr1]-nociceptin, a novel nociceptin analog, decreases systemic arterial pressure by a naloxone-insensitive mechanism in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

[Tyr1]-nociceptin has naloxone-insensitive vasodilator activity in the hindquarters vascular bed of the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Activation of Type II Adenylyl Cyclase by the Cloned μ‐Opioid Receptor: Coupling to Multiple G Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Pertussis Toxin-Insensitive Signaling of the ORL1 Receptor: Coupling to Gz and G16 Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Specific receptor for the opioid peptide dynorphin: structure--activity relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Profound inhibition of cardiomotor neurons in the rat rostral ventrolateral medulla by nociceptin (orphanin FQ).

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Effect of nociceptin on alcohol intake in alcohol-preferring rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin receptor coupling to a potassium conductance in rat locus coeruleus neurones in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The effect of nociceptin on Ca2+ channel current and intracellular Ca2+ in the SH-SY5Y human neuroblastoma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin, an endogenous ligand for the ORL1 receptor, has vasodilator activity in the hindquarters vascular bed of the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The orphanin FQ system: an emerging target for the management of pain?

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ/nociceptin: a role in pain and analgesia, but so much more

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin (Orphanin FQ) abolishes gestational and ovarian sex steroid-induced antinociception and induces hyperalgesia.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The reorganization of mu opioid receptors in the rat dorsal horn following peripheral axotomy

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Simultaneous activation of spinal antiopioid system (neuropeptide FF) and pain facilitatory circuitry by stimulation of opioid receptors in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The novel neuropeptide orphanin FQ fails to produce conditioned place preference or aversion.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ: receptor binding and analog structure activity relationships in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Inward Rectification (I) in Immunocytochemically-ldentified Vasopressin and Oxytocin Neurons of Guinea-Pig Supraoptic Nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Electrophysiology of guinea-pig supraoptic neurones: role of a hyperpolarization-activated cation current in phasic firing.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Cloning of a delta opioid receptor by functional expression

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Depression of glutamatergic transmission by nociceptin in the neonatal rat hemisected spinal cord preparation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin activation of the human ORL1 receptor expressed in Chinese hamster ovary cells: functional homology with opioid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin stimulates locomotion and exploratory behaviour in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Primary structures and expression from cDNAs of rat opioid receptor delta- and mu-subtypes.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

cDNA cloning and regional distribution of a novel member of the opioid receptor family.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Activation of phospholipase A2 by the nociceptin receptor expressed in Chinese hamster ovary cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Identification in the mu-opioid receptor of cysteine residues responsible for inactivation of ligand binding by thiol alkylating and reducing agents

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Intrathecal Tyr-W-MIF-1 produces potent, naloxone-reversible analgesia modulated by alpha 2-adrenoceptors

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Analgesic effects of Tyr-W-MIF-1: a mixed mu2-opioid receptor agonist/mu1-opioid receptor antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Neuropeptide FF receptors of mouse olfactory bulb: binding properties and stimulation of adenylate cyclase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Endorphin-mediated increases in pain threshold during pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Modulation of enkephalin release by nociceptin (orphanin FQ).

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Prejunctional modulation by nociceptin of nerve-mediated inotropic responses in guinea-pig left atrium

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Effect of nociceptin on heart rate and blood pressure in anaesthetized rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Regulation of mu binding sites after chronic administration of antibodies directed against specific anti-opiate peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Role of opioid receptors in the spinal antinociceptive effects of neuropeptide FF analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

A new selective antagonist of the nociceptin receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin: an endogenous agonist for central opioid like1 (ORL1) receptors possesses systemic vasorelaxant properties

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Lack of cross-tolerance between the antinociceptive effect of intrathecal orphanin FQ and morphine in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Anti-hyperalgesic and anti-allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Characterization of nociceptin hyperalgesia and allodynia in conscious mice

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Tyr-MIF-1 affects passive avoidance behavior but not motor activity in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Circuitry underlying antiopioid actions of orphanin FQ in the rostral ventromedial medulla.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Inhibition by nociceptin of neurogenic inflammation and the release of SP and CGRP from sensory nerve terminals

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The orphan opioid receptor and its endogenous ligand — nociceptin/orphanin FQ

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The GTP-binding protein, Go, regulates neuronal calcium channels

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Purification and properties of enkephalin — The possible endogenous ligand for the morphine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Functional coupling of the nociceptin/orphanin FQ receptor with the G-protein-activated K+ (GIRK) channel.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Distribution of prepro-nociceptin/orphanin FQ mRNA and its receptor mRNA in developing and adult mouse central nervous systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin/orphanin FQ binding increases in superficial laminae of the rat spinal cord during persistent peripheral inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Some principles in the peptide field

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

MIF-I's differential actions as an opiate antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Neuropeptide FF (FLQPQRFamide) and IgG from neuropeptide FF antiserum affect spatial learning in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Spinal analgesic activity of orphanin FQ/nociceptin and its fragments

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Modulation of voltage-gated calcium channels by orphanin FQ in freshly dissociated hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Differential modulation of alpha 2-adrenergic and mu-opioid spinal antinociception by neuropeptide FF.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Modification of dopamine release by nociceptin in conscious rat striatum.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

IgG from neuropeptide FF antiserum reverses morphine tolerance in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Comparison of the structure-activity relationships of nociceptin and dynorphin A using chimeric peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin hyperpolarises neurones in the rat ventromedial hypothalamus.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphan opioid receptor antisense probes block orphanin FQ-induced hyperphagia

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Opioids and consummatory behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Endogenous opioid peptides: multiple agonists and receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin/orphanin FQ activates protein kinase C, and this effect is mediated through phospholipase C/Ca2+ pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Specific-Opiate-Induced Depression of Transmitter Release from Dorsal Root Ganglion Cells in Culture

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

FMRF-NH2-like mammalian peptide precipitates opiate-withdrawal syndrome in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

FMRF-NH2-like mammalian octapeptide: possible role in opiate dependence and abstinence.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Tyr-MIF-1 precipitates abstinence syndrome in morphine-dependent rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Enhancement of spatial attention in nociceptin/orphanin FQ receptor-knockout mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The cloned mu, delta and kappa receptors and their endogenous ligands: evidence for two opioid peptide recognition cores

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Postsynaptic mechanisms underlying responsiveness of amygdaloid neurons to nociceptin/orphanin FQ.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Physiological properties of unmyelinated fiber projection to the spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Moving from the orphanin FQ receptor to an opioid receptor using four point mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Cloning and pharmacological characterization of a rat kappa opioid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

MIF-1 and Tyr-MIF-1 augment GABA-stimulated benzodiazepine receptor binding.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Cloning and expression of a cDNA for the rat kappa-opioid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ is a functional anti-opioid peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Replacement of Gln280 by His in TM6 of the human ORL1 receptor increases affinity but reduces intrinsic activity of opioids.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

ORL-1 and mu opioid receptor antisera label different fibers in areas involved in pain processing

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Antinociception mediated by the periaqueductal gray is attenuated by orphanin FQ.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Neuropeptide FF reduces food intake in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ/nociceptin blocks acquisition of morphine place preference.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Intracerebroventricular orphanin FQ/nociceptin suppresses dopamine release in the nucleus accumbens of anaesthetized rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ/nociceptin modulation of mesolimbic dopamine transmission determined by microdialysis

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ and behavioral sensitization to cocaine.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Inhibition by nociceptin of the light-evoked release of ACh from retinal cholinergic neurones

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin induced inhibition of K+ evoked glutamate release from rat cerebrocortical slices

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

cDNA cloning and pharmacological characterization of an opioid receptor with high affinities for kappa-subtype-selective ligands.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Primary structure and tissue distribution of the orphanin FQ precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Biphasic effect on nociception and antiopiate activity of the neuropeptide FF (FLFQPQRFamide) in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

G alpha 15 and G alpha 16 couple a wide variety of receptors to phospholipase C

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Naloxone-insensitive inhibition of acetylcholine release from parasympathetic nerves innervating guinea-pig trachea by the novel opioid, nociceptin

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Distribution of nociceptin/orphanin FQ receptor transcript in human central nervous system and immune cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Endocrine actions of opioids

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Neuropeptide FF reverses the effect of mu-opioid on Ca2+ channels in rat spinal ganglion neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Structure-activity relationship studies on the novel neuropeptide orphanin FQ.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Structures that delineate orphanin FQ and dynorphin A pharmacological selectivities

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Neurophysiology and neuropharmacology of hypothalamic magnocellular neurons secreting vasopressin and oxytocin

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ/nociceptin-immunoreactive nerve fibers parallel those containing endogenous opioids in rat spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Naloxone sensitive orphanin FQ-induced analgesia in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

A review of the role of anti-opioid peptides in morphine tolerance and dependence

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Chronic intracerebroventricular infusion of the antiopioid peptide, Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 (NPFF), downregulates mu opioid binding sites in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Effects of neuropeptide FF on intracellular Ca2+ in mouse spinal ganglion neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Molecular Cloning and Characterization of a Novel Form of Neuropeptide Gene as a Developmentally Regulated Molecule

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Overexpression of a neuropeptide nociceptin/orphanin FQ precursor gene, N23K/N27K, induces neurite outgrowth in mouse NS20Y cells

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin/orphanin FQ microinjected into hippocampus impairs spatial learning in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

In vivo metabolism of nociceptin/orphanin FQ in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin/orphanin FQ and opioid peptides show overlapping distribution but not co-localization in pain-modulatory brain regions.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Studies on inhibition of mu and delta opioid receptor binding by dithiothreitol and N-ethylmaleimide. His223 is critical for mu opioid receptor binding and inactivation by N-ethylmaleimide

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ/nociceptin in the ventromedial nucleus facilitates lordosis in female rats

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Cyclic AMP analogs induce synthesis, processing, and secretion of prepro nociceptin/orphanin FQ-derived peptides by NS20Y neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Activation of an inwardly rectifying K+ conductance by orphanin-FQ/nociceptin in vasopressin-containing neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Changes in CNS neuropeptide FF-like material, pain sensitivity, and opiate dependence following chronic morphine treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Injections of nociceptin into nucleus accumbens shell or ventromedial hypothalamic nucleus increase food intake.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Metabolic fate of nociceptin/orphanin FQ in the rat spinal cord and biological activity of its released fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Cloning and pharmacological characterization of a rat mu opioid receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Involvement of endogenous orphanin FQ in electroacupuncture-induced analgesia.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Endogenous orphanin FQ: evidence for a role in the modulation of electroacupuncture analgesia and the development of tolerance to analgesia produced by morphine and electroacupuncture

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Partial loss of tolerance liability to morphine analgesia in mice lacking the nociceptin receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Prolyl-leucyl-glycinamide (PLG) facilitates morphine dependence

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Increase by the ORL1 receptor (opioid receptor-like1) ligand, nociceptin, of inwardly rectifying K conductance in dorsal raphe nucleus neurones.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Actions of the ORL1 receptor ligand nociceptin on membrane properties of rat periaqueductal gray neurons in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The peptide orphanin FQ inhibits beta-endorphin neurons and neurosecretory cells in the hypothalamic arcuate nucleus by activating an inwardly-rectifying K+ conductance

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Nociceptin fails to affect heroin self-administration in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Prolyl-leucyl-glycinamide, cyclo(leucylglycine), and derivatives block development of physical dependence on morphine in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Distinct effect of intracerebroventricular and intrathecal injections of nociceptin/orphanin FQ in the rat formalin test.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

cDNA cloning of an orphan opiate receptor gene family member and its splice variant

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned mu, delta, and kappa opioid receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

The role of cholecystokinin in nociception, neuropathic pain and opiate tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Effects of intrathecally administered nociceptin, an opioid receptor-like1 receptor agonist, and N-methyl-D-aspartate receptor antagonists on the thermal hyperalgesia induced by partial sciatic nerve injury in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Effects of intrathecally administered nociceptin, an opioid receptor-like1 (ORL1) receptor agonist, on the thermal hyperalgesia induced by unilateral constriction injury to the sciatic nerve in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Analgesic effect of intrathecally administered nociceptin, an opioid receptor-like1 receptor agonist, in the rat formalin test

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Effects of intrathecally administered nociceptin, an opioid receptor-like1 (ORL1) receptor agonist, on the thermal hyperalgesia induced by carageenan injection into the rat paw.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Isolation, sequencing, synthesis, and pharmacological characterization of two brain neuropeptides that modulate the action of morphine

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Cloning and functional comparison of kappa and delta opioid receptors from mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Accelerated release and production of orphanin FQ in brain of chronic morphine tolerant rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Interactions between the antiopiate Tyr-MIF-1 and the mu opiate morphiceptin at their respective binding sites in brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Chronic, but not acute, administration of morphine alters antiopiate (Tyr-MIF-1) binding sites in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Prolonged analgesia after intracerebroventricular Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2).

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Tyr-MIF-1 and hemorphin can act as opiate agonists as well as antagonists in the guinea pig ileum

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Characterization of binding sites for N-Tyr-MIF-1 (Tyr-Pro-Leu-Gly-NH2) in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ has an inhibitory effect on the guinea pig ileum and the mouse vas deferens.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

OFQ reverses the kappa-opioid receptor-mediated depression of calcium current in rat dorsal root ganglion neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Down-regulation of mu-opioid receptors in rat and monkey dorsal root ganglion neurons and spinal cord after peripheral axotomy

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

TYR-MIF-1, but not MIF-1 or morphine, decreases cyclic AMP-dependent protein kinase activity extracted from HeLa cells

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

Orphanin FQ potentiates formalin-induced pain behavior and antagonizes morphine analgesia in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2899%2900185-0

7 January 2021

10.1016/S0196-9781(99)00185-0

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10704732