Characterization of a ranavirus inhibitor of the antiviral protein kinase PKR (Q33850280)

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25 January 2020

title

Characterization of a ranavirus inhibitor of the antiviral protein kinase PKR (English)

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25 January 2020

3

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25 January 2020

author name string

Stefan Rothenburg

series ordinal

1

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25 January 2020

V Gregory Chinchar

series ordinal

2

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25 January 2020

publication date

18 March 2011

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25 January 2020

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25 January 2020

volume

11

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25 January 2020

page(s)

56

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describes a project that uses

25 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3068933/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/1471-2180-11-56

0 references

cites work

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28 July 2018

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Double-stranded RNA-activated protein kinase PKR of fishes and amphibians: varying the number of double-stranded RNA binding domains and lineage-specific duplications

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ZBP1 subcellular localization and association with stress granules is controlled by its Z-DNA binding domains

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Interferon action and the double-stranded RNA-dependent enzymes ADAR1 adenosine deaminase and PKR protein kinase

28 July 2018

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28 July 2018

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A PKR-like eukaryotic initiation factor 2alpha kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domains

28 July 2018

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Molecular cloning and characterisation of a fish PKR-like gene from cultured CAB cells induced by UV-inactivated virus

28 July 2018

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28 July 2018

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Genomic sequence of a ranavirus (family Iridoviridae) associated with salamander mortalities in North America

28 July 2018

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Characterization of rainbow trout and zebrafish eukaryotic initiation factor 2alpha and its response to endoplasmic reticulum stress and IPNV infection

28 July 2018

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X-ray crystal structure and functional analysis of vaccinia virus K3L reveals molecular determinants for PKR subversion and substrate recognition

28 July 2018

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Sequence analysis of the complete genome of an iridovirus isolated from the tiger frog

28 July 2018

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Crystal structure of the N-terminal segment of human eukaryotic translation initiation factor 2alpha

28 July 2018

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28 July 2018

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Pseudosubstrate inhibition of protein kinase PKR by swine pox virus C8L gene product

28 July 2018

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A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR.

28 July 2018

1 reference

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Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain

28 July 2018

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Disruption of cellular translational control by a viral truncated eukaryotic translation initiation factor 2alpha kinase homolog

28 July 2018

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Regulation of the protein kinase PKR by the vaccinia virus pseudosubstrate inhibitor K3L is dependent on residues conserved between the K3L protein and the PKR substrate eIF2alpha.

28 July 2018

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Recombinant vaccinia virus K3L gene product prevents activation of double-stranded RNA-dependent, initiation factor 2 alpha-specific protein kinase

28 July 2018

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Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast

28 July 2018

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The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms

28 July 2018

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Modulation of tRNA(iMet), eIF-2, and eIF-2B expression shows that GCN4 translation is inversely coupled to the level of eIF-2.GTP.Met-tRNA(iMet) ternary complexes

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

28 July 2018

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28 July 2018

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The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

28 July 2018

1 reference

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Comparative genomic analyses of frog virus 3, type species of the genus Ranavirus (family Iridoviridae).

28 July 2018

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Cytoplasmic nucleic acid sensors in antiviral immunity

21 January 2018

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Binding of double-stranded RNA to protein kinase PKR is required for dimerization and promotes critical autophosphorylation events in the activation loop.

21 January 2018

1 reference

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The Atlantic salmon Z-DNA binding protein kinase phosphorylates translation initiation factor 2 alpha and constitutes a unique orthologue to the mammalian dsRNA-activated protein kinase R.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2180-11-56

Molecular cloning, characterization and expression analysis of the PKZ gene in rare minnow Gobiocypris rarus.

21 January 2018

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Functional domains and the antiviral effect of the double-stranded RNA-dependent protein kinase PKR from Paralichthys olivaceus

21 January 2018

1 reference

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Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2180-11-56

Inhibition of PKR by RNA and DNA viruses

21 January 2018

1 reference

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Partial mapping and sequencing of a fish iridovirus genome reveals genes homologous to the frog virus 3 p31, p40 and human eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2180-11-56

Comparison of the eIF-2alpha homologous proteins of seven ranaviruses (Iridoviridae).

21 January 2018

1 reference

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Rana catesbeiana virus Z (RCV-Z): a novel pathogenic ranavirus

21 January 2018

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Solution structure of human initiation factor eIF2alpha reveals homology to the elongation factor eEF1B

21 January 2018

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21 January 2018

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A Decade of Advances in Iridovirus Research

21 January 2018

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Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

21 January 2018

1 reference

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Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

21 January 2018

1 reference

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Import of proteins into mitochondria. Extramitochondrial pools and post-translational import of mitochondrial protein precursors in vivo

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21418572

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2180-11-56

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418572%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 January 2020

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1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21418572%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference