SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability (Q33847786)

29 July 2017

SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability (English)

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29 July 2017

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1 reference

John A Tainer

4

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author name string

Johanna Heideker

1

1 reference

29 July 2017

John Prudden

2

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29 July 2017

J Jefferson P Perry

3

1 reference

29 July 2017

Michael N Boddy

5

1 reference

29 July 2017

language of work or name

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3 March 2011

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29 July 2017

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29 July 2017

7

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29 July 2017

3

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29 July 2017

e1001320

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Creative Commons Attribution 4.0 International

29 July 2017

start time

3 March 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3048374/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Posttranslational modifications of repair factors and histones in the cellular response to stalled replication forks.

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An additional role for SUMO in ubiquitin-mediated proteolysis

5 July 2018

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Molecular mimicry of SUMO promotes DNA repair

5 July 2018

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Ubiquitin-family modifications of topoisomerase I in camptothecin-treated human breast cancer cells

5 July 2018

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The Yin and Yang of the MMS21-SMC5/6 SUMO ligase complex in homologous recombination

5 July 2018

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Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA.

5 July 2018

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Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase

5 July 2018

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Localization of Smc5/6 to centromeres and telomeres requires heterochromatin and SUMO, respectively

5 July 2018

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Single-strand break repair and genetic disease

5 July 2018

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A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes.

5 July 2018

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A SIM-ultaneous role for SUMO and ubiquitin

5 July 2018

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Mus81 is essential for sister chromatid recombination at broken replication forks

5 July 2018

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The role of Schizosaccharomyces pombe SUMO ligases in genome stability.

5 July 2018

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TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo

5 July 2018

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SUMO-targeted ubiquitin ligases in genome stability.

5 July 2018

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Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins

5 July 2018

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The Slx5-Slx8 complex affects sumoylation of DNA repair proteins and negatively regulates recombination

5 July 2018

1 reference

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Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

5 July 2018

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Role of SUMO in the dynamics of telomere maintenance in fission yeast

5 July 2018

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Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer

5 July 2018

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Topoisomerase I inhibitors: camptothecins and beyond

5 July 2018

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Repair of topoisomerase I-mediated DNA damage

5 July 2018

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Modification of proteins by ubiquitin and ubiquitin-like proteins

5 July 2018

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The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex

5 July 2018

1 reference

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Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae

5 July 2018

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A new SUMO ligase in the DNA damage response

5 July 2018

1 reference

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Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages

5 July 2018

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Mutual interactions between the SUMO and ubiquitin systems: a plea of no contest

5 July 2018

1 reference

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Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family

5 July 2018

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Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Nse1, Nse2, and a novel subunit of the Smc5-Smc6 complex, Nse3, play a crucial role in meiosis.

5 July 2018

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Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60.

5 July 2018

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Cohesins Determine the Attachment Manner of Kinetochores to Spindle Microtubules at Meiosis I in Fission Yeast

5 July 2018

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Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.

5 July 2018

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Yeast Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1 replicative damage

5 July 2018

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The Schizosaccharomyces pombe rad60 gene is essential for repairing double-strand DNA breaks spontaneously occurring during replication and induced by DNA-damaging agents.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Processing of nucleopeptides mimicking the topoisomerase I-DNA covalent complex by tyrosyl-DNA phosphodiesterase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Replication checkpoint enforced by kinases Cds1 and Chk1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Double-strand break-induced mitotic intrachromosomal recombination in the fission yeast Schizosaccharomyces pombe

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Does this have a familiar RING?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048374

Specific pathways prevent duplication-mediated genome rearrangements

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001320

Tdp1 protects against oxidative DNA damage in non-dividing fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001320

Does this have a familiar RING?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001320

SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001320

A vector system for genomic FLAG epitope-tagging in Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001320

Genome-wide localization of pre-RC sites and identification of replication origins in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001320

Ubiquitin, SUMO-1, and UCRP in camptothecin sensitivity and resistance

21 January 2018

1 reference

12 December 2020

Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin

1 reference

12 December 2020

The topoisomerase I poison camptothecin generates a Chk1-dependent DNA damage checkpoint signal in fission yeast

1 reference

12 December 2020

Trapping of DNA topoisomerase I on nick-containing DNA in cell free extracts of Saccharomyces cerevisiae

1 reference

12 December 2020

Trapping of human DNA topoisomerase I by DNA structures mimicking intermediates of DNA repair

1 reference

12 December 2020

Crosstalk between the SUMO and ubiquitin pathways

1 reference

12 December 2020

The genetic control of spontaneous and UV-induced mitotic intrachromosomal recombination in the fission yeast Schizosaccharomyces pombe

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1001320

Identifiers

DOI

1 reference

29 July 2017

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29 July 2017

1 reference