The epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolism (Q33846421)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24855646%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

The epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolism (English)

1 reference

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19 March 2020

5

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19 March 2020

author name string

Steve Poirier

1

1 reference

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19 March 2020

Samaneh Samami

2

1 reference

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19 March 2020

Maya Mamarbachi

3

1 reference

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19 March 2020

Annie Demers

4

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19 March 2020

Dennis E Vance

6

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19 March 2020

Grant M Hatch

7

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19 March 2020

Gaétan Mayer

8

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19 March 2020

language of work or name

English

0 references

publication date

22 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24855646%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

19 March 2020

published in

1 reference

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19 March 2020

volume

289

1 reference

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19 March 2020

issue

27

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19 March 2020

page(s)

18736-18751

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24855646%20AND%20SRC:MED&resulttype=core&format=json

The biology of PCSK9 from the endoplasmic reticulum to lysosomes: new and emerging therapeutics to control low-density lipoprotein cholesterol

19 March 2020

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5 July 2018

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5 July 2018

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Role of DNA methylation in the regulation of lipogenic glycerol-3-phosphate acyltransferase 1 gene expression in the mouse neonatal liver

5 July 2018

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Lipid droplet formation on opposing sides of the endoplasmic reticulum

5 July 2018

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Lipid metabolism in cancer

5 July 2018

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Azacitidine: a review of its use in the management of myelodysplastic syndromes/acute myeloid leukaemia

5 July 2018

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RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia

5 July 2018

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Lumenal lipid metabolism: implications for lipoprotein assembly

5 July 2018

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Alteration of lipids and the transcription of lipid-related genes in myelodysplastic syndromes via a TP53-related pathway.

5 July 2018

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The Scap/SREBP pathway is essential for developing diabetic fatty liver and carbohydrate-induced hypertriglyceridemia in animals

5 July 2018

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5 July 2018

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Epigenetic regulation in myelodysplastic syndromes: implications for therapy

5 July 2018

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Inhibition of SREBP by a Small Molecule, Betulin, Improves Hyperlipidemia and Insulin Resistance and Reduces Atherosclerotic Plaques

5 July 2018

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Accessibility of cholesterol in endoplasmic reticulum membranes and activation of SREBP-2 switch abruptly at a common cholesterol threshold

5 July 2018

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Structural determinants for the inhibitory ligands of orotidine-5′-monophosphate decarboxylase

5 July 2018

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GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis

5 July 2018

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A comparison of azacitidine and decitabine activities in acute myeloid leukemia cell lines

5 July 2018

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Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine

5 July 2018

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The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Decreased Hepatic Triglyceride Accumulation and Altered Fatty Acid Uptake in Mice with Deletion of the Liver Fatty Acid-binding Protein Gene

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Sterol-dependent transcriptional regulation of sterol regulatory element-binding protein-2.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Enzymatic synthesis of cytidine diphosphate diglyceride

5 July 2018

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Biological effects of 5-azacytidine in eukaryotes

5 July 2018

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The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M114.563650

Patients with myelodysplastic syndromes display several T-cell expansions, which are mostly polyclonal in the CD4(+) subset and oligoclonal in the CD8(+) subset.

21 January 2018

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Crossref

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cAMP analogues inhibit phosphatidylcholine biosynthesis in cultured rat hepatocytes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24855646

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Plasma membrane fractions from rat liver contain a phosphatidate phosphohydrolase distinct from that in the endoplasmic reticulum and cytosol

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24855646

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.563650

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24855646%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24855646%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24855646%20AND%20SRC:MED&resulttype=core&format=json