ESAT-6 inhibits production of IFN-gamma by Mycobacterium tuberculosis-responsive human T cells (Q33846096)

29 July 2017

ESAT-6 inhibits production of IFN-gamma by Mycobacterium tuberculosis-responsive human T cells (English)

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Mycobacterium tuberculosis

29 July 2017

0 references

author name string

Xisheng Wang

1

1 reference

29 July 2017

Peter F Barnes

2

1 reference

29 July 2017

Karen M Dobos-Elder

3

1 reference

29 July 2017

James C Townsend

4

1 reference

29 July 2017

Yoon-tae Chung

5

1 reference

29 July 2017

Homayoun Shams

6

1 reference

29 July 2017

Stephen E Weis

7

1 reference

29 July 2017

Buka Samten

8

1 reference

29 July 2017

language of work or name

English

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publication date

1 March 2009

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29 July 2017

Journal of Immunology

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29 July 2017

182

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29 July 2017

3668-3677

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29 July 2017

6

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Delayed protection by ESAT-6-specific effector CD4+ T cells after airborne M. tuberculosis infection

29 July 2017

1 reference

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Secreted transcription factor controls Mycobacterium tuberculosis virulence

5 July 2018

1 reference

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CREB, ATF, and AP-1 transcription factors regulate IFN-gamma secretion by human T cells in response to mycobacterial antigen

5 July 2018

1 reference

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An antibody against the surfactant protein A (SP-A)-binding domain of the SP-A receptor inhibits T cell-mediated immune responses to Mycobacterium tuberculosis.

5 July 2018

1 reference

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Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis

5 July 2018

1 reference

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Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs

5 July 2018

1 reference

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Mycobacterium tuberculosis 6-kDa early secreted antigenic target (ESAT-6) protein downregulates lipopolysaccharide induced c-myc expression by modulating the extracellular signal regulated kinases 1/2

5 July 2018

1 reference

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Rational design of vaccines against tuberculosis directed by basic immunology

5 July 2018

1 reference

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ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity

5 July 2018

1 reference

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Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages

5 July 2018

1 reference

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Protein secretion systems in Mycobacteria.

5 July 2018

1 reference

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The ESAT6 protein of Mycobacterium tuberculosis induces apoptosis of macrophages by activating caspase expression

5 July 2018

1 reference

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Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction

5 July 2018

1 reference

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1 reference

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Structure and function of the complex formed by the tuberculosis virulence factors CFP-10 and ESAT-6

5 July 2018

1 reference

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Protective effect of a tuberculosis subunit vaccine based on a fusion of antigen 85B and ESAT-6 in the aerosol guinea pig model

5 July 2018

1 reference

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A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion

5 July 2018

1 reference

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Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion

5 July 2018

1 reference

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Protein-protein interactions of proteins from the ESAT-6 family of Mycobacterium tuberculosis

5 July 2018

1 reference

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The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue

5 July 2018

1 reference

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Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system

5 July 2018

1 reference

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Identification and characterization of the ESAT-6 homologue of Mycobacterium leprae and T-cell cross-reactivity with Mycobacterium tuberculosis

5 July 2018

1 reference

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Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications

5 July 2018

1 reference

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Human macrophage activation programs induced by bacterial pathogens

5 July 2018

1 reference

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Molecular and immunological characterization of Mycobacterium tuberculosis CFP-10, an immunodiagnostic antigen missing in Mycobacterium bovis BCG

5 July 2018

1 reference

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Novel human immunodeficiencies reveal the essential role of type-I cytokines in immunity to intracellular bacteria

5 July 2018

1 reference

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5 July 2018

1 reference

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Key epitopes on the ESAT-6 antigen recognized in mice during the recall of protective immunity to Mycobacterium tuberculosis.

5 July 2018

1 reference

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Complex complexes: signaling at the TCR.

5 July 2018

1 reference

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Novel insights into the genetics, biochemistry, and immunocytochemistry of the 30-kilodalton major extracellular protein of Mycobacterium tuberculosis

5 July 2018

1 reference

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Evidence for occurrence of the ESAT-6 protein in Mycobacterium tuberculosis and virulent Mycobacterium bovis and for its absence in Mycobacterium bovis BCG.

5 July 2018

1 reference

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Disseminated tuberculosis in interferon gamma gene-disrupted mice

5 July 2018

1 reference

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Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells

5 July 2018

1 reference

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Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice.

5 July 2018

1 reference

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Negative transcriptional regulation of the interferon-gamma promoter by glucocorticoids and dominant negative mutants of c-Jun

5 July 2018

1 reference

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Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis

5 July 2018

1 reference

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T-cell cytokine responses in human infection with Mycobacterium tuberculosis

5 July 2018

1 reference

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Differentiation of the T helper phenotypes by analysis of the methylation state of the IFN-gamma gene.

5 July 2018

1 reference

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An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection

5 July 2018

1 reference

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Proteins released from Mycobacterium tuberculosis during growth.

5 July 2018

1 reference

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Human immune response to Mycobacterium tuberculosis antigens

5 July 2018

1 reference

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Type VII secretion--mycobacteria show the way.

5 July 2018

1 reference

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Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo.

29 October 2018

1 reference

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Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex formation, virulence, and immunogenicity.

29 October 2018

1 reference

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Cyclic AMP response element-binding protein positively regulates production of IFN-gamma by T cells in response to a microbial pathogen

29 October 2018

1 reference

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29 October 2018

1 reference

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29 October 2018

1 reference

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29 October 2018

1 reference

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The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms.

29 October 2018

1 reference

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29 October 2018

1 reference

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29 October 2018

1 reference

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29 October 2018

1 reference

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12 December 2020

Synergistic Effect of Bacillus Calmette Guerin and a Tuberculosis Subunit Vaccine in Cationic Liposomes: Increased Immunogenicity and Protection

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Differential T cell responses to Mycobacterium tuberculosis ESAT6 in tuberculosis patients and healthy donors

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Regulation of the activity of IFN-gamma promoter elements during Th cell differentiation

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Mycobacterial virulence and specialized secretion: same story, different ending

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The Proximal Regulatory Element of the Interferon-γ Promoter Mediates Selective Expression in T Cells

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Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6

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Identifiers

DOI

10.4049/JIMMUNOL.0803579

1 reference

29 July 2017

1 reference

29 July 2017

1 reference