The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease (Q33841363)

29 July 2017

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title

The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer's disease (English)

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29 July 2017

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Valerio Leoni

1

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29 July 2017

1 March 2011

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Clinical Chemistry and Laboratory Medicine

29 July 2017

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29 July 2017

49

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29 July 2017

375-383

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29 July 2017

3

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https://api.crossref.org/works/10.1515%2FCCLM.2011.088

29 July 2017

1 reference

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Cholesterol as a risk factor for Alzheimer's disease - epidemiological evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Mild cognitive impairment: clinical characterization and outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Mild Cognitive Impairment Can Be Distinguished From Alzheimer Disease and Normal Aging for Clinical Trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Genetic connections between neurological disorders and cholesterol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Apolipoprotein E and cholesterol in aging and disease in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

The role of apolipoprotein E in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Outsourcing in the brain: do neurons depend on cholesterol delivery by astrocytes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

The role of tau in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Implication of apoE isoforms in cholesterol metabolism by primary rat hippocampal neurons and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

The C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Amyloid beta peptide alters intracellular vesicle trafficking and cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

The clinical use of structural MRI in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Atrophy rates accelerate in amnestic mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

CSF biomarkers in prediction of cerebral and clinical change in mild cognitive impairment and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Relations between brain tissue loss, CSF biomarkers, and the ApoE genetic profile: a longitudinal MRI study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Age effects on atrophy rates of entorhinal cortex and hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Longitudinal MRI atrophy biomarkers: relationship to conversion in the ADNI cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Longitudinal stability of CSF biomarkers in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Serial MRI and CSF biomarkers in normal aging, MCI, and AD

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Longitudinal study of CSF biomarkers in patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Longitudinal CSF and MRI biomarkers improve the diagnosis of mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Increasing CSF phospho-tau levels during cognitive decline and progression to dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Correlation of longitudinal cerebrospinal fluid biomarkers with cognitive decline in healthy older adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

CSF biomarkers predict rate of cognitive decline in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment: a follow-up study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Rapid progression from mild cognitive impairment to Alzheimer's disease in subjects with elevated levels of tau in cerebrospinal fluid and the APOE epsilon4/epsilon4 genotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Do CSF total tau, phosphorylated tau, and beta-amyloid 42 help to predict progression of mild cognitive impairment to Alzheimer's disease? A systematic review and meta-analysis of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

CSF Abeta42, Tau and phosphorylated Tau, APOE epsilon4 allele and MCI type in progressive MCI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer type

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

MRI and CSF biomarkers in normal, MCI, and AD subjects: diagnostic discrimination and cognitive correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.088

21 January 2018

Identifiers

DOI

10.1515/CCLM.2011.088

1 reference

release_v2a2lxhbanefnarwavcwcppdke

29 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/v2a2lxhbanefnarwavcwcppdke

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

21388338

1 reference

PubMed ID

21388338