Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception (Q33840778)

29 July 2017

Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception (English)

1 reference

29 July 2017

Shen Yue

1

1 reference

29 July 2017

Liu-Ya Tang

2

1 reference

29 July 2017

Ying Tang

3

1 reference

29 July 2017

Yi Tang

4

1 reference

29 July 2017

Qiu-Hong Shen

5

1 reference

29 July 2017

Jie Ding

6

1 reference

29 July 2017

Yan Chen

7

1 reference

29 July 2017

Zengdi Zhang

8

1 reference

29 July 2017

Ting-Ting Yu

9

1 reference

29 July 2017

Ying E Zhang

10

1 reference

29 July 2017

Steven Y Cheng

11

1 reference

29 July 2017

language of work or name

English

0 references

publication date

12 June 2014

1 reference

29 July 2017

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29 July 2017

3

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describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4080449/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Medulloblastomics: the end of the beginning

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

The Hedgehog signal transduction network

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Regulation of endocytic clathrin dynamics by cargo ubiquitination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Patched dependence receptor triggers apoptosis through ubiquitination of caspase-9.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Hedgehog secretion and signal transduction in vertebrates

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

HECT and RING finger families of E3 ubiquitin ligases at a glance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Epithelial stem cells, wound healing and cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Clathrin-independent endocytosis: mechanisms and function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Dual Phosphorylation of suppressor of fused (Sufu) by PKA and GSK3beta regulates its stability and localization in the primary cilium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Caveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Interactions between Hedgehog proteins and their binding partners come into view

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Role of lipid metabolism in smoothened derepression in hedgehog signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Lipid rafts, caveolae, and their endocytosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

The primary cilium: a signalling centre during vertebrate development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Differential modulation of Sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Establishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedback

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Regulation of planar cell polarity by Smurf ubiquitin ligases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Two patched protein subtypes and a conserved domain of group I proteins that regulates turnover

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Beta-arrestin-mediated localization of smoothened to the primary cilium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Patched1 regulates hedgehog signaling at the primary cilium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Proteasome-independent functions of ubiquitin in endocytosis and signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Lipid raft microdomains and neurotransmitter signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Boc is a receptor for sonic hedgehog in the guidance of commissural axons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Vertebrate Smoothened functions at the primary cilium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Hh pathway expression in human gut tissues and in inflammatory gut diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Hedgehog interacting protein in the mature brain: membrane-associated and soluble forms.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Hedgehog signalling in the mouse requires intraflagellar transport proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Modulation of developmental signals by endocytosis: different means and many ends.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

The vertebrate primary cilium is a sensory organelle

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Patched acts catalytically to suppress the activity of Smoothened

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Dual roles for patched in sequestering and transducing Hedgehog

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Regulation of the synthesis and assembly of ciliary and flagellar proteins during regeneration

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

Mouse cerebellar granule neurons arrest the proliferation of human and rodent astrocytoma cells in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20.

28 July 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Sonic hedgehog induces the segregation of patched and smoothened in endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Hedgehog signaling in development and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Endocytosis conducts the cell signaling orchestra

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Lymphocytic choriomeningitis virus uses a novel endocytic pathway for infectious entry via late endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Patching the gaps in Hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

The ihog cell-surface proteins bind Hedgehog and mediate pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.7554%2FELIFE.02555

Subcellular localization of the segment polarity protein patched suggests an interaction with the wingless reception complex in Drosophila embryos.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4080449

29 October 2018

Identifiers

DOI

10.7554/ELIFE.02555

1 reference

29 July 2017

1 reference

29 July 2017

1 reference