What role for biologically based dose-response models in estimating low-dose risk? (Q33837778)

29 July 2017

3 references

19 June 2019

19 September 2019

27 September 2020

What role for biologically based dose-response models in estimating low-dose risk? (English)

1 reference

biomedical investigative technique

29 July 2017

1 reference

impact of the environment

19 September 2019

1 reference

27 September 2020

5

Christopher J Portier

1 reference

29 July 2017

Kenny S Crump

1

1 reference

29 July 2017

Chao Chen

2

1 reference

29 July 2017

Weihsueh A Chiu

3

1 reference

29 July 2017

Thomas A Louis

4

1 reference

29 July 2017

Ravi P Subramaniam

6

1 reference

29 July 2017

Paul D White

7

1 reference

29 July 2017

4 January 2010

1 reference

29 July 2017

1 May 2010

3 references

19 June 2019

19 September 2019

27 September 2020

4

1 reference

Environmental Health Perspectives

inferred from page(s)

published in

4 references

29 July 2017

19 June 2019

19 September 2019

27 September 2020

118

1 reference

29 July 2017

5

1 reference

29 July 2017

585-588

1 reference

Risk Assessment in the Federal Government

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Competitive inhibition of thyroidal uptake of dietary iodide by perchlorate does not describe perturbations in rat serum total T4 and TSH

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

How can biologically-based modeling of arsenic kinetics and dynamics inform the risk assessment process? - A workshop review.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Heterogeneity in multistage carcinogenesis and mixture modeling

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Toxicology. Transforming environmental health protection

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Uncertainties in the CIIT model for formaldehyde-induced carcinogenicity in the rat: a limited sensitivity analysis-I.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

A systems-based computational model for dose-response comparisons of two mode of action hypotheses for ethanol-induced neurodevelopmental toxicity.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on initiation and promotion of GST-P-positive foci in rat liver: A quantitative analysis of experimental data using a stochastic model

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Biologically based dose-response model for liver tumors induced by trichloroethylene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Quantitative assessment of the risk of lung cancer associated with occupational exposure to refractory ceramic fibers.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Modeling the number and size of hepatic focal lesions following exposure to 2,3,7,8-TCDD.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Radon, cigarette smoke, and lung cancer: a re-analysis of the Colorado Plateau uranium miners' data.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Growth kinetics of enzyme-altered liver foci in rats treated with phenobarbital or alpha-hexachlorocyclohexane.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

A stochastic two-stage model for cancer risk assessment. I. The hazard function and the probability of tumor.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Cigarette smoking and lung cancer: reanalysis of the British doctors' data

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

A stochastic two-stage carcinogenesis model: a new approach to computing the probability of observing tumor in animal bioassays

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Commentary on "Toxicity testing in the 21st century: implications for human health risk assessment" by Krewski et al.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Sensitivity analysis of biologically motivated model for formaldehyde-induced respiratory cancer in humans.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Human respiratory tract cancer risks of inhaled formaldehyde: dose-response predictions derived from biologically-motivated computational modeling of a combined rodent and human dataset.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Biologically motivated computational modeling of formaldehyde carcinogenicity in the F344 rat.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Toward a biologically based dose-response model for developmental toxicity of 5-fluorouracil in the rat: a mathematical construct

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

A model for hepatocarcinogenesis treating phenotypical changes in focal hepatocellular lesions as epigenetic events.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

A multistage model of carcinogenesis incorporating DNA damage and repair.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Hepatic Foci in Rats after Diethylnitrosamine Initiation and 2,3,7,8-Tetrachlorodibenzo-p-dioxin Promotion: Evaluation of a Quantitative Two-Cell Model and of CYP 1A1/1A2 as a Dosimeter

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2866670

Quantitative analysis of enzyme-altered liver foci in rats initiated with diethylnitrosamine and promoted with 2,3,7,8-tetrachlorodibenzo-p-dioxin or 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin

29 October 2018

1 reference

12 December 2020

Formaldehyde risk assessment

1 reference

12 December 2020

Use of mechanistic models to estimate low-dose cancer risks

1 reference

12 December 2020

Estimation of unit risk for coke oven emissions

1 reference

12 December 2020

Limitations of biological models of carcinogenesis for low-dose extrapolation

1 reference

12 December 2020

Science and trans-science

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.0901249

1 reference

29 July 2017

1 reference

29 July 2017

1 reference