A new approach to risk estimation of food-borne carcinogens--heterocyclic amines--based on molecular information (Q33828701)

29 July 2017

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title

A new approach to risk estimation of food-borne carcinogens--heterocyclic amines--based on molecular information (English)

1 reference

29 July 2017

M Nagao

1

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PubMed ID

10656481

29 July 2017

language of work or name

English

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publication date

1 December 1999

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29 July 2017

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29 July 2017

431

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29 July 2017

1

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29 July 2017

3-12

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Carcinogenic Action of N-Methyl-N′-nitro-N-nitrosoguanidine

29 July 2017

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An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

7 January 2021

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Environmental mutagens and carcinogens

7 January 2021

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Mutagenicities of smoke condensates and the charred surface of fish and meat

7 January 2021

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Mutagenicities of protein pyrolysates

7 January 2021

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Prophage lambda induction of Escherichia coli K12 envA uvrB: a highly sensitive test for potential carcinogens

7 January 2021

1 reference

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Carcinogenicities of heterocyclic amines in cooked food

7 January 2021

1 reference

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Carcinogenicity of 2-Amino-3-methylimidazo[4,5-f]quinoline in Nonhuman Primates: Induction of Tumors in Three Macaques

7 January 2021

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Identification of a mutagenic substance in a spice, sumac, as quercetin

7 January 2021

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Mutagenicities of 61 flavonoids and 11 related compounds.

7 January 2021

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Test of carcinogenicity of quercetin, a widely distributed mutagen in food

7 January 2021

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The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today

7 January 2021

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Formation of a mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) in cooked beef, by heating a mixture containing creatinine, phenylalanine and glucose

7 January 2021

1 reference

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Formation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in a model system by heating creatinine, glycine and glucose

7 January 2021

1 reference

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Carcinogenic heterocyclic amines in model systems and cooked foods: a review on formation, occurrence and intake.

7 January 2021

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Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1.

7 January 2021

1 reference

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Selectivity of Polycyclic Inhibitors for Human Cytochrome P450s 1A1, 1A2, and 1B1

7 January 2021

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Species differences in the N-acetylation by liver cytosol of mutagenic heterocyclic aromatic amines in protein pyrolysates

7 January 2021

1 reference

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Adduct formation at C-8 of guanine on in vitro reaction of the ultimate form of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine with 2'-deoxyguanosine and its phosphate esters.

7 January 2021

1 reference

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In vitro formation and degradation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) protein adducts.

7 January 2021

1 reference

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Identification of N2-(deoxyguanosin-8-yl)-2-amino-3,8-dimethyl-imidazo[4,5- f]quinoxaline 3',5'-diphosphate, a major DNA adduct, detected by nuclease P1 modification of the 32P-postlabeling method, in the liver of rats fed MeIQx

7 January 2021

1 reference

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Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research

7 January 2021

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Multiple steps in carcinogenesis, multiple carcinogenic factors, and multiple primary tumors: can we develop an appropriate response for cancer prevention?

7 January 2021

1 reference

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32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.

7 January 2021

1 reference

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Lack of carcinogenicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in cynomolgus monkeys.

7 January 2021

1 reference

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32P-postlabeling analysis of DNA adducts persisting for up to 42 weeks in the skin, epidermis and dermis of mice treated topically with 7,12-dimethylbenz[a]anthracene.

7 January 2021

1 reference

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Detection of guanine-C8-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine adduct as a single spot on thin-layer chromatography by modification of the 32P-postlabeling method.

7 January 2021

1 reference

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A new modification of the 32P-post-labeling method to recover IQ-DNA adducts as mononucleotides

7 January 2021

1 reference

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Presence of N2-(deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (dG-C8-MeIQx) in human tissues.

7 January 2021

1 reference

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Analysis of DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine in rat and human tissues by alkaline hydrolysis and gas chromatography/electron capture mass spectrometry: validation by comparison with 32P-postlabeling

7 January 2021

1 reference

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Human exposure to carcinogenic heterocyclic amines and their mutational fingerprints in experimental animals

7 January 2021

1 reference

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DNA modification by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rats

7 January 2021

1 reference

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DNA adduct level induced by 2-amino-3,4-dimethylimidazo[4,5-f]-quinoline in Big Blue mice does not correlate with mutagenicity.

7 January 2021

1 reference

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No direct correlation between mutant frequencies and cancer incidence induced by MeIQ in various organs of Big Blue mice

7 January 2021

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Comparison between in vivo mutagenicity and carcinogenicity in multiple organs by benzo[a]pyrene in the lacZ transgenic mouse (Muta Mouse).

7 January 2021

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A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

7 January 2021

1 reference

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Effects of gender and species on spectra of mutation induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the lacI transgene.

7 January 2021

1 reference

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DNA adduct formation, cell proliferation and aberrant crypt focus formation induced by PhIP in male and female rat colon with relevance to carcinogenesis.

7 January 2021

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Genetic determinant and environmental carcinogens

7 January 2021

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Rare frequency of activation of the Ki-ras gene in rat colon tumors induced by heterocyclic amines: possible alternative mechanisms of human colon carcinogenesis

7 January 2021

1 reference

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Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

7 January 2021

1 reference

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Agreement of mutational characteristics of heterocyclic amines in lacI of the Big Blue mouse with those in tumor related genes in rodents.

7 January 2021

1 reference

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Preferential induction of guanine deletion at 5'-GGGA-3' in rat mammary glands by 2-amino- 1-methyl-6-phenylimidazo[4,5-b]pyridine.

7 January 2021

1 reference

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Genetic analysis of PHIP intestinal mutations in MutaMouse

7 January 2021

1 reference

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Mutational spectra of the dietary carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine(PhIP) at the Chinese hamsters hprt locus.

7 January 2021

1 reference

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TP53 tumor suppressor gene: a model for investigating human mutagenesis

7 January 2021

1 reference

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10.1016/S0027-5107(99)00154-2

7 January 2021

Identifiers

DOI

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29 July 2017

1 reference

PubMed ID

10656481