Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors (Q33824623)

29 July 2017

Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors (English)

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29 July 2017

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By Gan Zhao

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29 July 2017

John P Vasilakos

2

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29 July 2017

Debra Tross

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29 July 2017

Dmitri Smirnov

4

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29 July 2017

Dennis M Klinman

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29 July 2017

13 May 2014

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Journal for Immunotherapy of Cancer

29 July 2017

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29 July 2017

2

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29 July 2017

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https://scigraph.springernature.com/pub.10.1186/2051-1426-2-12

29 July 2017

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Innate immune recognition

4 July 2018

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

4 July 2018

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Immune-mediated eradication of tumors through the blockade of transforming growth factor-beta signaling in T cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075973

A Toll-like receptor recognizes bacterial DNA

4 July 2018

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Structural analysis of CTLA-4 function in vivo

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075973

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075973

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075973

CTLA-4 can function as a negative regulator of T cell activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075973

TLR ligands in the local treatment of established intracerebral murine gliomas.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075973

Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075973

NK- and CD8(+) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4075973

Efficient chemokine-dependent migration and primary and secondary IL-12 secretion by human dendritic cells stimulated through Toll-like receptors

29 October 2018

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12 December 2020

Interferon-gamma produced by interleukin-12-activated tumor infiltrating CD8+T cells directly induces apoptosis of mouse hepatocellular carcinoma

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12 December 2020

Immune-mediated tumor regression induced by CpG-containing oligodeoxynucleotides

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12 December 2020

Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

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12 December 2020

The role of CpG motifs in innate immunity

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12 December 2020

Combined TLR stimulation with Pam3Cys and Poly I: C enhances Flt3-ligand dendritic cell activation for tumor immunotherapy

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12 December 2020

The TLR7 agonist R848 alleviates allergic inflammation by targeting invariant NKT cells to produce IFN-gamma

1 reference

12 December 2020

Vaccine adjuvant activity of 3M-052: an imidazoquinoline designed for local activity without systemic cytokine induction

1 reference

12 December 2020

Induction of systemic TH1-like innate immunity in normal volunteers following subcutaneous but not intravenous administration of CPG 7909, a synthetic B-class CpG oligodeoxynucleotide TLR9 agonist

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12 December 2020

Identifiers

DOI

10.1186/2051-1426-2-12

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Dimensions Publication ID

29 July 2017

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1 reference

29 July 2017

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