Activated memory CD4(+) T helper cells repopulate the intestine early following antiretroviral therapy of simian immunodeficiency virus-infected rhesus macaques but exhibit a decreased potential to produce interleukin-2 (Q33817369)

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English	Activated memory CD4(+) T helper cells repopulate the intestine early following antiretroviral therapy of simian immunodeficiency virus-infected rhesus macaques but exhibit a decreased potential to produce interleukin-2	scientific article

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scholarly article

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10 December 2019

Activated memory CD4(+) T helper cells repopulate the intestine early following antiretroviral therapy of simian immunodeficiency virus-infected rhesus macaques but exhibit a decreased potential to produce interleukin-2 (English)

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10 December 2019

anti-retroviral agent

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Simian immunodeficiency virus

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Zeljka Smit-McBride

2

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10 December 2019

author name string

J J Mattapallil

1

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10 December 2019

P Dailey

3

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10 December 2019

S Dandekar

4

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publication date

1 August 1999

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10 December 2019

Journal of Virology

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10 December 2019

73

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10 December 2019

8

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10 December 2019

6661-6669

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10 December 2019

Gastrointestinal epithelium is an early extrathymic site for increased prevalence of CD34(+) progenitor cells in contrast to the thymus during primary simian immunodeficiency virus infection

1 reference

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4 July 2018

Peripheral expansion of pre-existing mature T cells is an important means of CD4+ T-cell regeneration HIV-infected adults.

1 reference

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4 July 2018

Gastrointestinal T lymphocytes retain high potential for cytokine responses but have severe CD4(+) T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes

1 reference

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4 July 2018

Intestinal intraepithelial lymphocytes are primed for gamma interferon and MIP-1beta expression and display antiviral cytotoxic activity despite severe CD4(+) T-cell depletion in primary simian immunodeficiency virus infection

1 reference

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4 July 2018

Effect of combination antiretroviral therapy upon rectal mucosal HIV RNA burden and mononuclear cell apoptosis

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4 July 2018

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

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4 July 2018

Correlation of virus load in plasma and lymph node tissue in human immunodeficiency virus infection. INCAS Study Group. Italy, Netherlands, Canada, Australia, and (United) States

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4 July 2018

A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team

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4 July 2018

Intestinal epithelial cell line induction of T cell differentiation from bone marrow precursors

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4 July 2018

9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian immunodeficiency virus infection in infant rhesus macaques

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4 July 2018

Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop

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4 July 2018

Alterations in the immune response of human immunodeficiency virus (HIV)-infected subjects treated with an HIV-specific protease inhibitor, ritonavir

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4 July 2018

Distribution of SIV infection in the gastrointestinal tract of rhesus macaques at early and terminal stages of AIDS.

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4 July 2018

Expression of costimulatory molecule CD28 on T cells in human immunodeficiency virus type 1 infection: functional and clinical correlations

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4 July 2018

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

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4 July 2018

Rapid and precise quantification of HIV-1 RNA in plasma using a branched DNA signal amplification assay

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4 July 2018

Dual binding capacity of mucosal immunoblasts to mucosal and synovial endothelium in humans: dissection of the molecular mechanisms

1 reference

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4 July 2018

Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine

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4 July 2018

Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men. HIV affects the immune system before CD4+ T helper cell depletion occurs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112750

4 July 2018

Lymphocyte proliferative responses to human immunodeficiency virus antigens in vitro

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4 July 2018

Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=112750

4 July 2018

In vivo activity against HIV and favorable toxicity profile of 2',3'-dideoxyinosine

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4 July 2018

Selective loss of T cell functions in different stages of HIV infection. Early loss of anti-CD3-induced T cell proliferation followed by decreased anti-CD3-induced cytotoxic T lymphocyte generation in AIDS-related complex and AIDS.

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4 July 2018

Nonhuman primate models for evaluation of AIDS therapy

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4 July 2018

Enhancement of HIV-specific cytotoxic T lymphocyte responses by zidovudine (AZT) treatment

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4 July 2018

Functional dichotomy of CD4+ T helper lymphocytes in asymptomatic human immunodeficiency virus infection

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4 July 2018

Changes in T-helper cell function in human immunodeficiency virus-infected children during didanosine therapy as a measure of antiretroviral activity

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4 July 2018

Peripheral engraftment of fetal intestine into athymic mice sponsors T cell development: direct evidence for thymopoietic function of murine small intestine

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4 July 2018

Reconstitution of long-term T helper cell function after zidovudine therapy in human immunodeficiency virus-infected patients

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4 July 2018

Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation.

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30 October 2018

Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy

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30 October 2018

Differences in viral distribution and cell adhesion molecule expression in the intestinal tract of rhesus macaques infected with pathogenic and nonpathogenic SIV.

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30 October 2018

Primary acute simian immunodeficiency virus infection of intestinal lymphoid tissue is associated with gastrointestinal dysfunction

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30 October 2018

Development of malabsorption and nutritional complications in simian immunodeficiency virus-infected rhesus macaques

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30 October 2018

In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus

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30 October 2018

Zidovudine-induced restoration of cell-mediated immunity to mycobacteria in immunodeficient HIV-infected patients

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30 October 2018

Correlation between immunologic function and clinical subpopulations of patients with the acquired immune deficiency syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of long-term zidovudine treatment on cell-mediated immune response and lymphokine production

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphocytes from HIV-infected individuals show aberrant inositol polyphosphate metabolism which reverses after zidovudine therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmentation of Cellular Immune Function during the Early Phase of Zidovudine Treatment of AIDS Patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ cell turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ cell turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of (R)-9-(2-phosphonylmethoxypropyl)adenine monotherapy on chronic SIV infection in macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of the Th1 to Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiretroviral agent (R)-9-(2-phosphonomethoxypropyl)adenine stimulates cytokine and nitric oxide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic variability of lymphocyte populations in peripheral blood and lymph nodes from HIV-infected individuals and the impact of antiretroviral therapy. DATRI 003 Study Group. Division of AIDS Treatment Research Initiative

1 reference

https://pubmed.ncbi.nlm.nih.gov/10400763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.73.8.6661-6669.1999

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1 reference

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10 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10400763%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

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