Genetic polymorphisms in human xenobiotica metabolizing enzymes as susceptibility factors in toxic response (Q33816089)

29 July 2017

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title

Genetic polymorphisms in human xenobiotica metabolizing enzymes as susceptibility factors in toxic response (English)

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29 July 2017

Autrup H

1

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29 July 2017

language of work or name

English

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publication date

1 January 2000

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29 July 2017

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29 July 2017

volume

464

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29 July 2017

issue

1

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29 July 2017

page(s)

65-76

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Carcinogen metabolism in cultured human tissues and cells

29 July 2017

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Study of the frequencies of CYP1A1 gene polymorphisms and glutathione S-transferase mu1 gene in primary breast cancers: an update with an additional 114 cases

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Aromatic DNA adducts in foundry workers in relation to exposure, life style and CYP1A1 and glutathione transferase M1 genotype.

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Modulation of DNA adduct levels in human mononuclear white blood cells and granulocytes by CYP1A1 CYP2D6 and GSTM1 genetic polymorphisms

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Contribution of genetic and nutritional factors to DNA damage in heavy smokers.

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Polycyclic aromatic hydrocarbon-DNA adducts in human placenta and modulation by CYP1A1 induction and genotype

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p53 gene mutations, and CYP1A1 and GSTM1 genotypes in pulmonary squamous cell carcinomas

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Variability in loss of constitutional heterozygosity across loci and among individuals: association with candidate genes in ductal breast carcinoma

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Associations between cytochrome P4502E1 genotype, mutagen sensitivity, cigarette smoking and susceptibility to lung cancer

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Genetic metabolic polymorphisms and the risk of cancer: a review of the literature

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A molecular epidemiology study in women from Upper Silesia, Poland.

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DNA adducts in human placenta as related to air pollution and to GSTM1 genotype

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Biomarkers for exposure to ambient air pollution--comparison of carcinogen-DNA adduct levels with other exposure markers and markers for oxidative stress

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Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk.

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Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1

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7 January 2021

Cytogenetic monitoring of occupational exposure to pesticides: characterization of GSTM1, GSTT1, and NAT2 genotypes

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7 January 2021

Cytogenetic markers of susceptibility: influence of polymorphic carcinogen-metabolizing enzymes

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p53, but not p16 mutations in oral squamous cell carcinomas are associated with specific CYP1A1 and GSTM1 polymorphic genotypes and patient tobacco use

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Polymorphic enzymes of xenobiotic metabolism as modulators of acquired P53 mutations in bladder cancer

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Human glutathione S-transferase T1-1 enhances mutagenicity of 1,2-dibromoethane, dibromomethane and 1,2,3,4-diepoxybutane in Salmonella typhimurium

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7 January 2021

Induction of sister chromatid exchange by 1,2-epoxy-3-butene in cultured human lymphocytes: influence of GSTT1 genotype

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7 January 2021

Assessment of exposure to butadiene in the process industry

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7 January 2021

Interactions between genetic predisposition and environmental toxicants for development of lung cancer

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7 January 2021

The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function

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7 January 2021

Benzene exposure, glutathione S-transferase theta homozygous deletion, and sister chromatid exchanges

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7 January 2021

Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning

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7 January 2021

Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxide of chrysene.

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Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons.

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7 January 2021

The glutathione S-transferase GSTP1 polymorphism: effects on susceptibility to oral/pharyngeal and laryngeal carcinomas.

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7 January 2021

Placental expression of arylamine N-acetyltransferases: evidence for linkage disequilibrium between NAT1*10 and NAT2*4 alleles of the two human arylamine N-acetyltransferase loci NAT1 and NAT2

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7 January 2021

Recombinant rat and hamster N-acetyltransferases-1 and -2: relative rates of N-acetylation of arylamines and N,O-acyltransfer with arylhydroxamic acids

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7 January 2021

The impact of interindividual variation in NAT2 activity on benzidine urinary metabolites and urothelial DNA adducts in exposed workers

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7 January 2021

Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens

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Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.

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Relationship between hprt mutant frequency, aromatic DNA adducts and genotypes for GSTM1 and NAT2 in bus maintenance workers

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7 January 2021

Relation between the occurrence of K-ras gene point mutations and genotypes of polymorphic N-acetyltransferase in human colorectal carcinomas.

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7 January 2021

Somatic mutations, acetylator status, and prognosis in colorectal cancer

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7 January 2021

Post-transcriptional regulation of human microsomal epoxide hydrolase

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7 January 2021

Human microsomal epoxide hydrolase: 5'-flanking region genetic polymorphisms

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7 January 2021

Microsomal epoxide hydrolase polymorphism as a risk factor for ovarian cancer

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7 January 2021

Increased frequency of a null-allele for NAD(P)H: quinone oxidoreductase in patients with urological malignancies

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7 January 2021

Genetic polymorphisms in human liver phenol sulfotransferases involved in the bioactivation of N-hydroxy derivatives of carcinogenic arylamines and heterocyclic amines

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7 January 2021

Sulfation of alpha-hydroxytamoxifen catalyzed by human hydroxysteroid sulfotransferase results in tamoxifen-DNA adducts

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7 January 2021

10.1016/S1383-5718(99)00167-9

Identifiers

DOI

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29 July 2017

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