Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure (Q33810485)

29 July 2017

Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure (English)

1 reference

29 July 2017

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Ashley G Henderson

1

1 reference

29 July 2017

Camille Ehre

2

1 reference

29 July 2017

Brian Button

3

1 reference

29 July 2017

Lubna H Abdullah

4

1 reference

29 July 2017

Li-Heng Cai

5

1 reference

29 July 2017

Margaret W Leigh

6

1 reference

29 July 2017

Genevieve C DeMaria

7

1 reference

29 July 2017

Hiro Matsui

8

1 reference

29 July 2017

Scott H Donaldson

9

1 reference

29 July 2017

C William Davis

10

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29 July 2017

John K Sheehan

11

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29 July 2017

Richard C Boucher

12

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29 July 2017

Mehmet Kesimer

13

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29 July 2017

language of work or name

English

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publication date

2 June 2014

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Journal of Clinical Investigation

29 July 2017

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29 July 2017

124

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29 July 2017

7

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29 July 2017

3047-3060

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Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Sputum biomarkers of inflammation and lung function decline in children with cystic fibrosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Mapping the protein domain structures of the respiratory mucins: a mucin proteome coverage study

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Mass spectrometric analysis of mucin core proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Serine proteases degrade airway mucins in cystic fibrosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Airway mucus function and dysfunction

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Analyzing the functions of large glycoconjugates through the dissipative properties of their absorbed layers using the gel-forming mucin MUC5B as an example

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Sputum biomarkers of inflammation in cystic fibrosis lung disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Airway surface dehydration in cystic fibrosis: pathogenesis and therapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

A morphometric study of mucins and small airway plugging in cystic fibrosis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Characterizing mucous cell remodeling in cystic fibrosis: relationship to neutrophils

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Regulation of mucin genes in chronic inflammatory airway diseases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Cystic fibrosis since 1938.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Chronic airway infection/inflammation induces a Ca2+i-dependent hyperinflammatory response in human cystic fibrosis airway epithelia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

The nature of small-airway obstruction in chronic obstructive pulmonary disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Antimicrobial polypeptides in host defense of the respiratory tract

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Identification of MUC5B, MUC5AC and small amounts of MUC2 mucins in cystic fibrosis airway secretions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Rapid size distribution and purity analysis of gastric mucus glycoproteins by size exclusion chromatography/multi angle laser light scattering

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Different mucins are produced by the surface epithelium and the submucosa in human trachea: identification of MUC5AC as a major mucin from the goblet cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Identification of glycoproteins on nitrocellulose membranes and gels

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

The viscoelasticity of fractionated canine tracheal mucus.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Distribution of early structural lung changes due to cystic fibrosis detected with chest computed tomography.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Mapping of the 45M1 epitope to the C-terminal cysteine-rich part of the human MUC5AC mucin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Well-differentiated human airway epithelial cell cultures.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Mucins and their O-Glycans from human bronchial epithelial cell cultures

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

New monoclonal antibodies to non-glycosylated domains of the secreted mucins MUC5B and MUC7.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Risk Factors for Bronchiectasis in Children with Cystic Fibrosis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4072023

Characterization of mucins from cultured normal human tracheobronchial epithelial cells.

30 October 2018

1 reference

12 December 2020

Salivary mucin MG1 is comprised almost entirely of different glycosylated forms of the MUC5B gene product

1 reference

12 December 2020

Quantitation of inflammatory responses to bacteria in young cystic fibrosis and control patients

1 reference

12 December 2020

MUC5AC and MUC5B mucins increase in cystic fibrosis airway secretions during pulmonary exacerbation

1 reference

12 December 2020

Identification of a nonmucin glycoprotein (gp-340) from a purified respiratory mucin preparation: evidence for an association involving the MUC5B mucin

1 reference

12 December 2020

Airway mucus in cystic fibrosis

1 reference

12 December 2020

Sputum viscosity in cystic fibrosis of the pancreas and other pulmonary diseases

1 reference

12 December 2020

Human respiratory tract secretion. Mucous glycoproteins of nonpurulent tracheobronchial secretions, and sputum of patients with bronchitis and cystic fibrosis

1 reference

12 December 2020

Biochemical properties of tracheobronchial mucins from cystic fibrosis and non-cystic fibrosis individuals

1 reference

12 December 2020

Evidence for the in vivo degradation of human respiratory mucins during Pseudomonas aeruginosa infection

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI73469

1 reference

29 July 2017

1 reference

29 July 2017

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