2-O, 3-O-desulfated heparin inhibits neutrophil elastase-induced HMGB-1 secretion and airway inflammation (Q33799602)

29 July 2017

2-O, 3-O-desulfated heparin inhibits neutrophil elastase-induced HMGB-1 secretion and airway inflammation (English)

1 reference

29 July 2017

1 reference

Kathryn L Griffin

1

1 reference

29 July 2017

Bernard M Fischer

2

1 reference

29 July 2017

Apparao B Kummarapurugu

3

1 reference

29 July 2017

Shuo Zheng

4

1 reference

29 July 2017

Thomas P Kennedy

5

1 reference

29 July 2017

Narayanam V Rao

6

1 reference

29 July 2017

W Michael Foster

7

1 reference

29 July 2017

Judith A Voynow

8

1 reference

29 July 2017

1 April 2014

1 reference

American Journal of Respiratory Cell and Molecular Biology

29 July 2017

1 reference

29 July 2017

50

1 reference

29 July 2017

4

1 reference

29 July 2017

684-689

1 reference

Sputum biomarkers and the prediction of clinical outcomes in patients with cystic fibrosis.

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Sputum biomarkers of inflammation and lung function decline in children with cystic fibrosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

High mobility group box-1 is phosphorylated by protein kinase C zeta and secreted in colon cancer cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

NAD(P)H quinone oxidoreductase 1 regulates neutrophil elastase-induced mucous cell metaplasia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

A CFTR potentiator in patients with cystic fibrosis and the G551D mutation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

High mobility group box 1 (HMGB1) activates an autophagic response to oxidative stress

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Effect of neutrophil elastase and its inhibitor EPI-hNE4 on transepithelial sodium transport across normal and cystic fibrosis human nasal epithelial cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Antiproteases as therapeutics to target inflammation in cystic fibrosis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Low anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Activation of the epithelial sodium channel (ENaC) by serine proteases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Potential role of high-mobility group box 1 in cystic fibrosis airway disease.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Proteases and cystic fibrosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

A segment of gamma ENaC mediates elastase activation of Na+ transport

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Systems biology of macrophages.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

The anti-inflammatory effects of heparin and related compounds

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Association between pulmonary function and sputum biomarkers in cystic fibrosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

EPI-hNE4, a proteolysis-resistant inhibitor of human neutrophil elastase and potential anti-inflammatory drug for treating cystic fibrosis.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

High-mobility group box 1 (HMGB1) protein: friend and foe.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Safety and efficacy of recombinant alpha(1)-antitrypsin therapy in cystic fibrosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Neutrophil elastase induces MUC5AC gene expression in airway epithelium via a pathway involving reactive oxygen species

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

HMG-1 as a late mediator of endotoxin lethality in mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Selective O-desulfation produces nonanticoagulant heparin that retains pharmacological activity in the lung.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

Functional macrophage cell lines transformed by abelson leukemia virus

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes.

4 July 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2013-0338RC

Risk Factors for Bronchiectasis in Children with Cystic Fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2013-0338RC

Heparin-disaccharide affects T cells: inhibition of NF-kappaB activation, cell migration, and modulation of intracellular signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2013-0338RC

Neutrophil elastase induces mucus cell metaplasia in mouse lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2013-0338RC

Serine proteases increase oxidative stress in lung cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4068925

alpha1-Antitrypsin inhalation reduces airway inflammation in cystic fibrosis patients

30 October 2018

1 reference

12 December 2020

Effect of inhaled heparin on allergen-induced early and late asthmatic responses in patients with atopic asthma

1 reference

12 December 2020

Neutrophil Elastase Degrades Cystic Fibrosis Transmembrane Conductance Regulator via Calpains and Disables Channel FunctionIn VitroandIn Vivo

1 reference

12 December 2020

Characteristics of EPI-hNE4 aerosol: a new elastase inhibitor for treatment of cystic fibrosis

1 reference

12 December 2020

Low-dose heparin inhibits acute graft versus host disease in mice

1 reference

12 December 2020

Muc-5/5ac mucin messenger RNA and protein expression is a marker of goblet cell metaplasia in murine airways

1 reference

12 December 2020

Identifiers

DOI

10.1165/RCMB.2013-0338RC

1 reference

29 July 2017

1 reference

29 July 2017

1 reference