AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons. (Q33791830)

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English	AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons.	scientific article

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AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons (English)

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Kimberly B Bjugstad

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J D Elsworth

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D E Redmond

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C Leranth

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J R Sladek

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T J Collier

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S B Foti

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R J Samulski

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K P Vives

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R H Roth

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15 February 2008

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Experimental Neurology

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1

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252-258

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4 January 2020

Differential effects of glial cell line-derived neurotrophic factor on A9 and A10 dopamine neuron survival in vitro

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4 July 2018

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4 July 2018

Assessment of GDNF in primate models of Parkinson's disease: comparison with human studies

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4 July 2018

Crossroads in GDNF therapy for Parkinson's disease

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4 July 2018

Dyskinesias and dopamine cell replacement in Parkinson's disease: a clinical perspective

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4 July 2018

Graft placement and uneven pattern of reinnervation in the striatum is important for development of graft-induced dyskinesia

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4 July 2018

Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor

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Dissociation between short-term increased graft survival and long-term functional improvements in Parkinsonian rats overexpressing glial cell line-derived neurotrophic factor.

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4 July 2018

Overexpression of glial cell line-derived neurotrophic factor using a lentiviral vector induces time- and dose-dependent downregulation of tyrosine hydroxylase in the intact nigrostriatal dopamine system.

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Transduction profiles of recombinant adeno-associated virus vectors derived from serotypes 2 and 5 in the nigrostriatal system of rats

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4 July 2018

Localized striatal delivery of GDNF as a treatment for Parkinson disease

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In vivo gene delivery of glial cell line--derived neurotrophic factor for Parkinson's disease

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4 July 2018

Neuroprotection for Parkinson's disease using viral vector-mediated delivery of GDNF.

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Cellular replacement therapy for Parkinson's disease--where we are today?

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4 July 2018

Effect of Prior Dopamine Denervation on Survival and Fiber Outgrowth from Intrastriatal Fetal Mesencephalic Grafts

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The GDNF family: signalling, biological functions and therapeutic value

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Transplantation of embryonic dopamine neurons for severe Parkinson's disease

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4 July 2018

Improving the survival of grafted dopaminergic neurons: a review over current approaches.

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Increased survival of dopaminergic neurons in striatal grafts of fetal ventral mesencephalic cells exposed to neurotrophin-3 or glial cell line-derived neurotrophic factor

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A glial cell line-derived neurotrophic factor-secreting clone of the Schwann cell line SCTM41 enhances survival and fiber outgrowth from embryonic nigral neurons grafted to the striatum and to the lesioned substantia nigra

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Long-term evaluation of bilateral fetal nigral transplantation in Parkinson disease

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Growth/differentiation factor 5 and glial cell line-derived neurotrophic factor enhance survival and function of dopaminergic grafts in a rat model of Parkinson's disease.

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Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue

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Topographical distribution of [125I]-glial cell line-derived neurotrophic factor in unlesioned and MPTP-lesioned rhesus monkey brain following a bolus intraventricular injection

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Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts

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Fetal nigral transplantation as a therapy for Parkinson's disease

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4 July 2018

GDNF enhances dopaminergic cell survival and fibre outgrowth in embryonic nigral grafts

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Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts

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GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

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Glial cell line-derived neurotrophic factor is expressed in the developing but not adult striatum and stimulates developing dopamine neurons in vivo

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Transplantation of embryonic marmoset dopaminergic neurons to the corpus striatum of marmosets rendered parkinsonian by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

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AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL.

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30 October 2018

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Regional and cell-specific expression of GDNF in rat brain

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30 October 2018

Early gestational mesencephalon grafts, but not later gestational mesencephalon, cerebellum or sham grafts, increase dopamine in caudate nucleus of MPTP-treated monkeys

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12 December 2020

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Striatal dopaminergic correlates of stable parkinsonism and degree of recovery in old-world primates one year after MPTP treatment

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12 December 2020

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10.1016/J.EXPNEUROL.2008.01.026

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4 January 2020

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