Deletion of astroglial CXCL10 delays clinical onset but does not affect progressive axon loss in a murine autoimmune multiple sclerosis model (Q33789063)

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English	Deletion of astroglial CXCL10 delays clinical onset but does not affect progressive axon loss in a murine autoimmune multiple sclerosis model	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

Deletion of astroglial CXCL10 delays clinical onset but does not affect progressive axon loss in a murine autoimmune multiple sclerosis model (English)

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Europe PubMed Central

29 July 2017

multiple sclerosis

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author name string

Emily Mills Ko

1

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Europe PubMed Central

29 July 2017

Joyce H Ma

2

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Europe PubMed Central

29 July 2017

Fuzheng Guo

3

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Europe PubMed Central

29 July 2017

Laird Miers

4

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Europe PubMed Central

29 July 2017

Eunyoung Lee

5

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Europe PubMed Central

29 July 2017

Peter Bannerman

6

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Europe PubMed Central

29 July 2017

Travis Burns

7

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Europe PubMed Central

29 July 2017

David Ko

8

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Europe PubMed Central

29 July 2017

Jiho Sohn

9

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Europe PubMed Central

29 July 2017

Athena M Soulika

10

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Europe PubMed Central

29 July 2017

David Pleasure

11

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Europe PubMed Central

29 July 2017

publication date

12 June 2014

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Europe PubMed Central

29 July 2017

Journal of Neuroinflammation

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Europe PubMed Central

29 July 2017

11

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Europe PubMed Central

29 July 2017

105

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Europe PubMed Central

29 July 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4066277/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1186/1742-2094-11-105

0 references

Macrophages migrate in an activation-dependent manner to chemokines involved in neuroinflammation

1 reference

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Astrocytes regulate myelin clearance through recruitment of microglia during cuprizone-induced demyelination

1 reference

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4 July 2018

IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066277

4 July 2018

CXCR3 ligands: redundant, collaborative and antagonistic functions

1 reference

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A semiautomated targeted sampling method to assess optic nerve axonal loss in a rat model of glaucoma

1 reference

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4 July 2018

Initiation and progression of axonopathy in experimental autoimmune encephalomyelitis

1 reference

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4 July 2018

Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS.

1 reference

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C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE.

1 reference

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4 July 2018

The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor

1 reference

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Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis

1 reference

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4 July 2018

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

1 reference

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4 July 2018

IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking

1 reference

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4 July 2018

Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons

1 reference

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4 July 2018

MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

1 reference

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4 July 2018

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066277

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Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activity

1 reference

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4 July 2018

Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066277

4 July 2018

Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state

1 reference

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4 July 2018

CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ T(H)-17 cells in relapsing EAE.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

CXCL10 (IFN-gamma-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

Neutralization of IFN-inducible protein 10/CXCL10 exacerbates experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

An antibody to IP-10 is a potent antagonist of cell migration in vitro and in vivo and does not affect disease in several animal models of inflammation

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

IFN-inducible protein 10/CXC chemokine ligand 10-independent induction of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

CXC chemokine receptors on human oligodendrocytes: implications for multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

Functional expression of CXCR3 in cultured mouse and human astrocytes and microglia.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

Th1-mediated experimental autoimmune encephalomyelitis is CXCR3 independent.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

Motor neuron pathology in experimental autoimmune encephalomyelitis: studies in THY1-YFP transgenic mice.

1 reference

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21 January 2018

IL-3 induces down-regulation of CCR3 protein and mRNA in human eosinophils

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

CXCR3 internalization following T cell-endothelial cell contact: preferential role of IFN-inducible T cell alpha chemoattractant (CXCL11).

1 reference

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21 January 2018

CXCL10/CXCR3 signaling in glia cells differentially affects NMDA-induced cell death in CA and DG neurons of the mouse hippocampus.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

CXCR3 Signaling Reduces the Severity of Experimental Autoimmune Encephalomyelitis by Controlling the Parenchymal Distribution of Effector and Regulatory T Cells in the Central Nervous System

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-11-105

21 January 2018

Mitogen-activated protein kinases (Erk1,2) phosphorylate Lys-Ser-Pro (KSP) repeats in neurofilament proteins NF-H and NF-M.

1 reference

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30 October 2018

CXCR3 chemokine receptor distribution in normal and inflamed tissues: expression on activated lymphocytes, endothelial cells, and dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4066277

30 October 2018

Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes: in vitro ERK1/2 activation and role in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24924222

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/24924222

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chemokine CXCL10 modulates excitatory activity and intracellular calcium signaling in cultured hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/24924222

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between internalization and mRNA decay in down-regulation of recombinant type 1 angiotensin II receptor (AT1) expression in smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24924222

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based on heuristic

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Multiple sclerosis: a study of CXCL10 and CXCR3 co-localization in the inflamed central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/24924222

12 December 2020

based on heuristic

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10.1186/1742-2094-11-105

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Europe PubMed Central

29 July 2017

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1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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