TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses. (Q33785096)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20375595%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses (English)

1 reference

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30 January 2020

0 references

1 reference

Narayanan Parameswaran

4

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30 January 2020

author name string

D M Appledorn

1

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30 January 2020

S Patial

2

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30 January 2020

S Godbehere

3

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30 January 2020

A Amalfitano

5

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30 January 2020

publication date

4 March 2009

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Journal of Innate Immunity

30 January 2020

published in

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30 January 2020

volume

1

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30 January 2020

issue

4

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30 January 2020

page(s)

376-388

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Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors

30 January 2020

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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4 July 2018

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Adenovirus-induced thrombocytopenia: the role of von Willebrand factor and P-selectin in mediating accelerated platelet clearance

4 July 2018

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Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo

4 July 2018

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Adenoviral infection induces a multi-faceted innate cellular immune response that is mediated by the toll-like receptor pathway in A549 cells

4 July 2018

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Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system.

4 July 2018

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Triggering TLR signaling in vaccination

4 July 2018

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Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105

4 July 2018

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Liver toxicities typically induced by first-generation adenoviral vectors can be reduced by use of E1, E2b-deleted adenoviral vectors

4 July 2018

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Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance

4 July 2018

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Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

4 July 2018

1 reference

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Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

4 July 2018

1 reference

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

4 July 2018

1 reference

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4 July 2018

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Adenoviral vectors do not induce, inhibit, or potentiate human platelet aggregation

4 July 2018

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Adenovirus vectors with the 100K gene deleted and their potential for multiple gene therapy applications

4 July 2018

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Production and characterization of improved adenovirus vectors with the E1, E2b, and E3 genes deleted

4 July 2018

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Wild-type adenoviruses from groups A-F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent

4 July 2018

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Role of MyD88 and TLR9 in the innate immune response elicited by serotype 5 adenoviral vectors

30 October 2018

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Type I IFN signaling on both B and CD4 T cells is required for protective antibody response to adenovirus

30 October 2018

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Type I interferon inhibits antibody responses induced by a chimpanzee adenovirus vector.

30 October 2018

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Toll-like receptor 9 triggers an innate immune response to helper-dependent adenoviral vectors.

30 October 2018

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Interference with the IL-1-signaling pathway improves the toxicity profile of systemically applied adenovirus vectors

30 October 2018

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Recombinant adenovirus vectors activate the alternative complement pathway, leading to the binding of human complement protein C3 independent of anti-ad antibodies

30 October 2018

1 reference

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Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages

30 October 2018

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PubMed

12 December 2020

1 reference

12 December 2020

Cutting edge: TLR2 directly triggers Th1 effector functions

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PubMed

12 December 2020

Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo

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PubMed

12 December 2020

Identifiers

DOI

10.1159/000207194

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20375595%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

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30 January 2020

PubMed publication ID

20375595

1 reference