Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments (Q33782408)

29 July 2017

Phosphorylation of cardiac troponin I at protein kinase C site threonine 144 depresses cooperative activation of thin filaments (English)

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29 July 2017

1 reference

Qun-Wei Lu

1

1 reference

29 July 2017

Aaron C Hinken

2

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29 July 2017

Stacey E Patrick

3

1 reference

29 July 2017

R John Solaro

4

1 reference

29 July 2017

Tomoyoshi Kobayashi

5

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29 July 2017

language of work or name

English

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publication date

17 February 2010

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Journal of Biological Chemistry

29 July 2017

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29 July 2017

285

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29 July 2017

16

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29 July 2017

11810-11817

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Ala scanning of the inhibitory region of cardiac troponin I.

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Sites of intra- and intermolecular cross-linking of the N-terminal extension of troponin I in human cardiac whole troponin complex

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Multiplex kinase signaling modifies cardiac function at the level of sarcomeric proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Unraveling molecular complexity of phosphorylated human cardiac troponin I by top down electron capture dissociation/electron transfer dissociation mass spectrometry

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Cardiac function and modulation of sarcomeric function by length

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Role of the acidic N' region of cardiac troponin I in regulating myocardial function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Negative charges at protein kinase C sites of troponin I stabilize the inactive state of actin

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Effects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin C

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Differential contribution of troponin I phosphorylation sites to the endothelin-modulated contractile response

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Calcium, thin filaments, and the integrative biology of cardiac contractility

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Cross-bridge versus thin filament contributions to the level and rate of force development in cardiac muscle

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Repriming the actomyosin crossbridge cycle

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Myosin crossbridge activation of cardiac thin filaments: implications for myocardial function in health and disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Covalent and noncovalent modification of thin filament action: the essential role of troponin in cardiac muscle regulation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Cardiac troponin T mutation R141W found in dilated cardiomyopathy stabilizes the troponin T-tropomyosin interaction and causes a Ca2+ desensitization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Cytoplasmic signaling pathways that regulate cardiac hypertrophy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Regulation of contraction in striated muscle

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

The ordered phosphorylation of cardiac troponin I by the cAMP-dependent protein kinase--structural consequences and functional implications

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Structural and functional domains of the troponin complex revealed by limited digestion

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

An essential myosin light chain peptide induces supramaximal stimulation of cardiac myofibrillar ATPase activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Thin filament-mediated regulation of cardiac contraction

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Bisphosphorylation of cardiac troponin I modulates the Ca(2+)-dependent binding of myosin subfragment S1 to reconstituted thin filaments.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Phosphorylation of both serine residues in cardiac troponin I is required to decrease the Ca2+ affinity of cardiac troponin C.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Functional chicken gizzard heavy meromyosin expression in and purification from baculovirus-infected insect cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Cardiac troponin I mutants. Phosphorylation by protein kinases C and A and regulation of Ca(2+)-stimulated MgATPase of reconstituted actomyosin S-1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Calcium-binding properties of troponin C in detergent-skinned heart muscle fibers.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Identification of sites phosphorylated in bovine cardiac troponin I and troponin T by protein kinase C and comparative substrate activity of synthetic peptides containing the phosphorylation sites

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Reversal of the cross-bridge force-generating transition by photogeneration of phosphate in rabbit psoas muscle fibres

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2852917

Cardiac troponin I threonine 144: role in myofilament length dependent activation

4 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Frequency- and afterload-dependent cardiac modulation in vivo by troponin I with constitutively active protein kinase A phosphorylation sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Cardiac transgenic and gene transfer strategies converge to support an important role for troponin I in regulating relaxation in cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Phosphorylation of troponin I controls cardiac twitch dynamics: evidence from phosphorylation site mutants expressed on a troponin I-null background in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Protein kinase C and A sites on troponin I regulate myofilament Ca2+ sensitivity and ATPase activity in the mouse myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Effects of phosphorylation and mutation R145G on human cardiac troponin I function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Studies on co-operative properties of tropomyosin-actin and tropomyosin-troponin-actin complexes by the use of N-ethylmaleimide-treated and untreated species of myosin subfragment 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Phosphorylation of troponin I by protein kinase A accelerates relaxation and crossbridge cycle kinetics in mouse ventricular muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Calcium- and myosin-dependent changes in troponin structure during activation of heart muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

The ATP hydrolysis and phosphate release steps control the time course of force development in rabbit skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Protein kinase A mediated modulation of acto-myosin kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Heart failure with preserved ejection fraction is characterized by dynamic impairment of active relaxation and contraction of the left ventricle on exercise and associated with myocardial energy deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Thin-filament-based modulation of contractile performance in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.055657

Some precautions in using chelators to buffer metals in biological solutions

21 January 2018

1 reference

12 December 2020

Inorganic phosphate speeds loaded shortening in rat skinned cardiac myocytes

1 reference

12 December 2020

Calcium binds cooperatively to the regulatory sites of the cardiac thin filament

1 reference

12 December 2020

Ordered phosphorylation of a duplicated minimal recognition motif for cAMP-dependent protein kinase present in cardiac troponin I

1 reference

12 December 2020

Reconstitution of skinned cardiac fibres with human recombinant cardiac troponin-I mutants and troponin-C

1 reference

12 December 2020

Introduction of negative charge mimicking protein kinase C phosphorylation of cardiac troponin I. Effects on cardiac troponin C

1 reference

12 December 2020

Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin I

1 reference

12 December 2020

PKC-betaII sensitizes cardiac myofilaments to Ca2+ by phosphorylating troponin I on threonine-144

1 reference

12 December 2020

Modulation of cardiac troponin C function by the cardiac-specific N-terminus of troponin I: influence of PKA phosphorylation and involvement in cardiomyopathies

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.055657

1 reference

release_wyiaunhrdngffjmja7tqhrmgta

29 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wyiaunhrdngffjmja7tqhrmgta

24 November 2022

mapped directly with Wikidata item

PMCID

2852917

1 reference

29 July 2017

1 reference