Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast (Q33781640)

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English	Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast	scientific article

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scholarly article

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Europe PubMed Central

29 July 2017

Requirement of PKR dimerization mediated by specific hydrophobic residues for its activation by double-stranded RNA and its antigrowth effects in yeast (English)

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Europe PubMed Central

29 July 2017

1 reference

based on heuristic

inferred from title

author name string

R C Patel

1

1 reference

Europe PubMed Central

29 July 2017

G C Sen

2

1 reference

Europe PubMed Central

29 July 2017

language of work or name

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publication date

1 December 1998

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Europe PubMed Central

29 July 2017

Molecular and Cellular Biology

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Europe PubMed Central

29 July 2017

18

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Europe PubMed Central

29 July 2017

7009-7019

1 reference

Europe PubMed Central

29 July 2017

12

1 reference

Europe PubMed Central

29 July 2017

Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways

1 reference

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A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

1 reference

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Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB

1 reference

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Characterization of the heparin-mediated activation of PKR, the interferon-inducible RNA-dependent protein kinase

1 reference

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Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR).

1 reference

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Mechanism of interferon action. Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells

1 reference

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The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans

1 reference

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Mutational analysis of the double-stranded RNA (dsRNA) binding domain of the dsRNA-activated protein kinase, PKR.

1 reference

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Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae

1 reference

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Characterization of the interactions between double-stranded RNA and the double-stranded RNA binding domain of the interferon induced protein kinase

1 reference

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Tumor-suppressor genes: news about the interferon connection

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Structure of the dsRNA binding domain of E. coli RNase III.

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NMR solution structure of a dsRNA binding domain from Drosophila staufen protein reveals homology to the N-terminal domain of ribosomal protein S5

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The interferon-inducible double-stranded RNA-activated protein kinase self-associates in vitro and in vivo

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Regulation of the interferon-induced PKR: can viruses cope?

1 reference

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28 July 2018

Role of the amino-terminal residues of the interferon-induced protein kinase in its activation by double-stranded RNA and heparin

1 reference

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The 58-kilodalton inhibitor of the interferon-induced double-stranded RNA-activated protein kinase is a tetratricopeptide repeat protein with oncogenic properties

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Mechanism of interferon action motif I of the interferon-induced, RNA-dependent protein kinase (PKR) is sufficient to mediate RNA-binding activity

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Growth-related expression of a double-stranded RNA-dependent protein kinase in 3T3 cells

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Characterization of a specific kinase inhibitory factor produced by vaccinia virus which inhibits the interferon-induced protein kinase

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A vector for expressing GAL4(1-147) fusions in mammalian cells

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The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation.

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A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

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The double stranded RNA-activated protein kinase induced by interferon: dsRNA-PK.

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Inhibitory activity for the interferon-induced protein kinase is associated with the reovirus serotype 1 sigma 3 protein

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Interaction of the human immunodeficiency virus type 1 Rev protein with a structured region in env mRNA is dependent on multimer formation mediated through a basic stretch of amino acids

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Measures and countermeasures in the modulation of initiation factor activities by viruses

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Translational control in mammalian cells

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Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system

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Modified subcellular localization of interferon-induced p68 kinase during encephalomyocarditis virus infection

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Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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A conserved double-stranded RNA-binding domain

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Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase

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Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase

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Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase

1 reference

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Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2

1 reference

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The vaccinia virus K3L gene product potentiates translation by inhibiting double-stranded-RNA-activated protein kinase and phosphorylation of the alpha subunit of eukaryotic initiation factor 2

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1 reference

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1 reference

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Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

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Gene induction by interferons and double-stranded RNA: selective inhibition by 2-aminopurine

1 reference

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The kinase insert domain of interferon-induced protein kinase PKR is required for activity but not for interaction with the pseudosubstrate K3L

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

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inferred from PubMed ID database lookup

Mechanism of interferon action. The interferon-induced phosphoprotein P1 possesses a double-stranded RNA-dependent ATP-binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

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based on heuristic

inferred from PubMed ID database lookup

Structure and regulation of eukaryotic initiation factor eIF-2. Sequence of the site in the alpha subunit phosphorylated by the haem-controlled repressor and by the double-stranded RNA-activated inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The double-stranded RNA-dependent protein kinase is also activated by heparin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophosphorylation of the protein kinase dependent on double-stranded RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Aminopurine selectively inhibits the induction of beta-interferon, c-fos, and c-myc gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon induction by viruses. XVI. 2-Aminopurine blocks selectively and reversibly an early stage in interferon induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two RNA-binding motifs in the double-stranded RNA-activated protein kinase, DAI

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockage of NF-kappa B signaling by selective ablation of an mRNA target by 2-5A antisense chimeras

1 reference

https://pubmed.ncbi.nlm.nih.gov/9819388

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.18.12.7009

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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