Characterization of protective human CD4CD25 FOXP3 regulatory T cells generated with IL-2, TGF-β and retinoic acid (Q33778359)

29 July 2017

Characterization of protective human CD4CD25 FOXP3 regulatory T cells generated with IL-2, TGF-β and retinoic acid (English)

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29 July 2017

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3

Julie Wang

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29 July 2017

Ling Lu

1

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29 July 2017

Xiaohui Zhou

series ordinal

2

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29 July 2017

Song Guo Zheng

series ordinal

4

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29 July 2017

David A Horwitz

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5

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29 July 2017

language of work or name

English

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publication date

17 December 2010

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29 July 2017

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29 July 2017

5

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29 July 2017

e15150

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29 July 2017

12

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Creative Commons Attribution 4.0 International

29 July 2017

start time

17 December 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells

4 July 2018

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Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines

4 July 2018

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Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?

4 July 2018

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Retinoic acid can directly promote TGF-beta-mediated Foxp3(+) Treg cell conversion of naive T cells

4 July 2018

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Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion

4 July 2018

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IL-17-producing human peripheral regulatory T cells retain suppressive function

4 July 2018

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Regulatory T cells in systemic lupus erythematosus: past, present and future

4 July 2018

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Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells

4 July 2018

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Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-beta-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression

4 July 2018

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Natural and TGF-beta-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other

4 July 2018

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Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

4 July 2018

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Polyclonal adaptive regulatory CD4 cells that can reverse type I diabetes become oligoclonal long-term protective memory cells

4 July 2018

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Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells.

4 July 2018

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Mitigation of experimental allergic encephalomyelitis by TGF-beta induced Foxp3+ regulatory T lymphocytes through the induction of anergy and infectious tolerance

4 July 2018

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The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

4 July 2018

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Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway

4 July 2018

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Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

4 July 2018

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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

4 July 2018

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CCR7 is required for the in vivo function of CD4+ CD25+ regulatory T cells

4 July 2018

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Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation

4 July 2018

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TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling

4 July 2018

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CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

4 July 2018

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Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development

4 July 2018

1 reference

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Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma

4 July 2018

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

4 July 2018

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

4 July 2018

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Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor.

4 July 2018

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CD8+ T cell-mediated suppression of autoimmunity in a murine lupus model of peptide-induced immune tolerance depends on Foxp3 expression.

21 January 2018

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Ex vivo generated regulatory T cells modulate experimental autoimmune myasthenia gravis

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Generation ex vivo of TGF-beta-producing regulatory T cells from CD4+CD25- precursors.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

CD4+ and CD8+ regulatory T cells generated ex vivo with IL-2 and TGF-beta suppress a stimulatory graft-versus-host disease with a lupus-like syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-{beta}.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Critical role of IL-2 and TGF-beta in generation, function and stabilization of Foxp3+CD4+ Treg.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

De novo generation and enhanced suppression of human CD4+CD25+ regulatory T cells by retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Human anti-inflammatory macrophages induce Foxp3+ GITR+ CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Alloantigen-specific de novo-induced Foxp3+ Treg revert in vivo and do not protect from experimental GVHD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Cutting edge: Foxp3+CD4+CD25+ regulatory T cells induced by IL-2 and TGF-beta are resistant to Th17 conversion by IL-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Loss of FOXP3 expression in natural human CD4+CD25+ regulatory T cells upon repetitive in vitro stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003689

CD4+CD25high regulatory cells in human peripheral blood

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3003689

Vitamin A Metabolites Induce Gut-Homing FoxP3+ Regulatory T Cells

30 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0015150

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

21 January 2018

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12 December 2020

Skin-versus gut-skewed homing receptor expression and intrinsic CCR4 expression on human peripheral blood CD4+CD25+ suppressor T cells

1 reference

12 December 2020

Transforming growth factor-beta 1-induced expression of the mucosa-related integrin alpha E on lymphocytes is not associated with mucosa-specific homing

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12 December 2020

Human regulatory T cells control xenogeneic graft-versus-host disease induced by autologous T cells in RAG2-/-gammac-/- immunodeficient mice

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12 December 2020

A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta

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12 December 2020

Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice

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12 December 2020

10.1371/JOURNAL.PONE.0015150

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DOI

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29 July 2017

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29 July 2017

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