14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo (Q33774875)

29 July 2017

14-3-3 facilitates Ras-dependent Raf-1 activation in vitro and in vivo (English)

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29 July 2017

Roy S

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29 July 2017

McPherson RA

2

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29 July 2017

Apolloni A

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29 July 2017

Yan J

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29 July 2017

Lane A

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29 July 2017

Clyde-Smith J

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29 July 2017

Hancock JF

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29 July 2017

language of work or name

English

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publication date

1 July 1998

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Molecular and Cellular Biology

29 July 2017

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29 July 2017

18

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29 July 2017

7

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29 July 2017

3947-3955

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Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

The complexity of Raf-1 regulation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

KSR modulates signal propagation within the MAPK cascade

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Control of the ERK MAP kinase cascade by Ras and Raf.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Inhibition of Raf/MAPK signaling in Xenopus oocyte extracts by Raf-1-specific peptides.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Negative regulation of Raf-1 by phosphorylation of serine 621.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Oligomerization activates c-Raf-1 through a Ras-dependent mechanism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

The activity of D-raf in torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

A novel role for RhoGDI as an inhibitor of GAP proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Plasma membrane-targeted ras GTPase-activating protein is a potent suppressor of p21ras function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Specific association of activated MAP kinase kinase kinase (Raf) with the plasma membranes of ras-transformed retinal cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Identification of the major phosphorylation sites of the Raf-1 kinase.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Mammalian Ras interacts directly with the serine/threonine kinase Raf

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

The cysteine-rich region of raf-1 kinase contains zinc, translocates to liposomes, and is adjacent to a segment that binds GTP-ras.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

A single amino acid change in Raf-1 inhibits Ras binding and alters Raf-1 function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Identification of discrete segments of human Raf-1 kinase critical for high affinity binding to Ha-Ras.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Interaction of the protein kinase Raf-1 with 14-3-3 proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Activation of Raf-1 by 14-3-3 proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Activation of Raf as a result of recruitment to the plasma membrane

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Two distinct Raf domains mediate interaction with Ras

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Phosphorylation of Raf by ceramide-activated protein kinase

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Physical association with ras enhances activation of membrane-bound raf (RafCAAX).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Sequential modification of serines 621 and 624 in the Raf-1 carboxyl terminus produces alterations in its electrophoretic mobility.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Lack of evidence for the activation of the Ras/Raf mitogenic pathway by 14-3-3 proteins in mammalian cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108979

Protein kinase C-mediated serine phosphorylation directly activates Raf-1 in murine hematopoietic cells

30 October 2018

1 reference

12 December 2020

The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex

1 reference

12 December 2020

Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase

1 reference

12 December 2020

Identification of the 14.3.3 zeta domains important for self-association and Raf binding

1 reference

12 December 2020

Negative Modulation of Membrane Localization of the Raf-1 Protein Kinase by Hyperphosphorylation

1 reference

12 December 2020

Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.18.7.3947

1 reference

29 July 2017

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29 July 2017

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