Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes (Q33767727)

29 July 2017

Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes (English)

1 reference

29 July 2017

Itai Benhar

13

0 references

David Baker

object named as

David Baker

10

0 references

Raffit Hassan

12

object named as

Raffit Hassan

1 reference

29 July 2017

9

Byungkook Lee

1 reference

29 July 2017

14

Ira Pastan

1 reference

29 July 2017

5

Masanori Onda

1 reference

29 July 2017

8

Robert J Kreitman

1 reference

29 July 2017

Ronit Mazor

1

1 reference

29 July 2017

Jaime A Eberle

2

1 reference

29 July 2017

Xiaobo Hu

3

1 reference

29 July 2017

Aaron N Vassall

4

1 reference

29 July 2017

Richard Beers

6

1 reference

29 July 2017

Elizabeth C Lee

7

1 reference

29 July 2017

Chris King

11

1 reference

29 July 2017

language of work or name

English

0 references

publication date

5 May 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

1 reference

29 July 2017

111

1 reference

29 July 2017

23

1 reference

29 July 2017

8571-8576

1 reference

Removing T-cell epitopes with computational protein design.

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Antibodies to watch in 2013: Mid-year update

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

A recombinant immunotoxin against the tumor-associated antigen mesothelin reengineered for high activity, low off-target toxicity, and reduced antigenicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Phase I trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Frequency of epitope-specific naive CD4(+) T cells correlates with immunodominance in the human memory repertoire

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotox

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Peptide binding predictions for HLA DR, DP and DQ molecules

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Molecular determinants of T cell epitope recognition to the common Timothy grass allergen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Phase I trial of continuous infusion anti-mesothelin recombinant immunotoxin SS1P.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Minimizing the immunogenicity of protein therapeutics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Recombinant immunotoxins in the treatment of cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Improving antibody affinity by mimicking somatic hypermutation in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

T cell-dependent B cell activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

The interpretation of protein structures: Estimation of static accessibility

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4060717

Immunogenicity of protein therapeutics

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1405153111

Elimination of an immunodominant CD4+ T cell epitope in human IFN-beta does not result in an in vivo response directed at the subdominant epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1405153111

Rationally engineered therapeutic proteins with reduced immunogenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1405153111

Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1405153111

Vaccination in humans generates broad T cell cytokine responses

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24799704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunodominance: a single amino acid substitution within an antigenic site alters intramolecular selection of T cell determinants

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24799704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24799704

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1405153111

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference