Evidence for proteolytic processing and stimulated organelle redistribution of iPLA(2)beta. (Q33763658)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132906%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Evidence for proteolytic processing and stimulated organelle redistribution of iPLA(2)beta (English)

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17 January 2020

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2

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17 January 2020

author name string

Haowei Song

1

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17 January 2020

Xiaoyong Lei

3

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17 January 2020

Chun Jin

4

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17 January 2020

Sheng Zhang

5

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17 January 2020

John Turk

6

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17 January 2020

Sasanka Ramanadham

7

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17 January 2020

language of work or name

English

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publication date

2 February 2010

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Biochimica et Biophysica Acta

17 January 2020

published in

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17 January 2020

volume

1801

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17 January 2020

issue

5

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17 January 2020

page(s)

547-558

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Skeletal muscle group VIA phospholipase A2 (iPLA2beta): expression and role in fatty acid oxidation

17 January 2020

cites work

1 reference

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Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis

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Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice

22 June 2018

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The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase.

22 June 2018

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Effects of stable suppression of Group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells

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Calcium-independent phospholipase A2 modulates cytosolic oxidant activity and contractile function in murine skeletal muscle cells

22 June 2018

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Genetic and pharmacologic evidence that calcium-independent phospholipase A2beta regulates virus-induced inducible nitric-oxide synthase expression by macrophages

22 June 2018

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Inhibition of calcium-independent phospholipase A2 activity in rat hippocampus impairs acquisition of short- and long-term memory

22 June 2018

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Increased calcium-independent phospholipase A2 activity in first but not in multiepisode chronic schizophrenia.

22 June 2018

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Characterization of N-terminal processing of group VIA phospholipase A2 and of potential cleavage sites of amyloid precursor protein constructs by automated identification of signature peptides in LC/MS/MS analyses of proteolytic digests

22 June 2018

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Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIbeta expressed in pancreatic islet beta-cells

22 June 2018

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Regulation of group VIA phospholipase A2 expression by sterol availability.

22 June 2018

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Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility.

22 June 2018

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Postsynaptic injection of calcium-independent phospholipase A2 inhibitors selectively increases AMPA receptor-mediated synaptic transmission

22 June 2018

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Beta-cell calcium-independent group VIA phospholipase A(2) (iPLA(2)beta): tracking iPLA(2)beta movements in response to stimulation with insulin secretagogues in INS-1 cells

22 June 2018

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Islet complex lipids: involvement in the actions of group VIA calcium-independent phospholipase A(2) in beta-cells

22 June 2018

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Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta

22 June 2018

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Pancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcript

22 June 2018

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CaM kinase IIalpha mediates norepinephrine-induced translocation of cytosolic phospholipase A2 to the nuclear envelope

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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Pancreatic islets express a Ca2+-independent phospholipase A2 enzyme that contains a repeated structural motif homologous to the integral membrane protein binding domain of ankyrin

22 June 2018

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The growing phospholipase A2 superfamily of signal transduction enzymes

22 June 2018

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22 June 2018

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Inhibition of calcium-independent phospholipase A2 prevents arachidonic acid incorporation and phospholipid remodeling in P388D1 macrophages

22 June 2018

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Cerebellar atrophy without cerebellar cortex hyperintensity in infantile neuroaxonal dystrophy (INAD) due to PLA2G6 mutation.

22 June 2018

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Mutations in PLA2G6 and the riddle of Schindler disease

30 October 2018

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iPLA2 inhibitor blocks negative inotropic effect of HIV gp120 on cardiac myocytes

30 October 2018

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Modulation of phospholipase A2 activity in primary cultures of rat cortical neurons

30 October 2018

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A novel role for phospholipase A2 isoforms in the checkpoint control of acute inflammation

30 October 2018

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Stimulation of insulin secretion and associated nuclear accumulation of iPLA(2)beta in INS-1 insulinoma cells

30 October 2018

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Studies of phospholipid metabolism, proliferation, and secretion of stably transfected insulinoma cells that overexpress group VIA phospholipase A2.

30 October 2018

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Calcium-independent phospholipase A(2) mediates CREB phosphorylation and c-fos expression during ischemia

30 October 2018

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Intracellular calcium signals regulating cytosolic phospholipase A2 translocation to internal membranes

30 October 2018

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Rat and human pancreatic islet cells contain a calcium ion independent phospholipase A2 activity selective for hydrolysis of arachidonate which is stimulated by adenosine triphosphate and is specifically localized to islet beta-cells

30 October 2018

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12 December 2020

Inhibition of arachidonate release by secretagogue-stimulated pancreatic islets suppresses both insulin secretion and the rise in beta-cell cytosolic calcium ion concentration

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12 December 2020

Role of Ca(2+)-independent phospholipase A(2) in the regulation of inducible nitric oxide synthase in cardiac myocytes

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12 December 2020

Glucose-responsitivity and expression of an ATP-stimulatable, Ca(2+)-independent phospholipase A2 enzyme in clonal insulinoma cell lines

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12 December 2020

Allelic association analysis of phospholipase A2 genes with schizophrenia

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12 December 2020

Anti-CD3 and concanavalin A-induced human T cell proliferation is associated with an increased rate of arachidonate-phospholipid remodeling. Lack of involvement of group IV and group VI phospholipase A2 in remodeling and increased susceptibility of

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12 December 2020

Studies of the role of group VI phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells

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12 December 2020

Ca2+-independent phospholipase A2 enhances store-operated Ca2+ entry in dystrophic skeletal muscle fibers

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12 December 2020

Electrospray ionization mass spectrometric analyses of phospholipids from INS-1 insulinoma cells: comparison to pancreatic islets and effects of fatty acid supplementation on phospholipid composition and insulin secretion

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12 December 2020

Characterization of an ATP-stimulatable Ca(2+)-independent phospholipase A2 from clonal insulin-secreting HIT cells and rat pancreatic islets: a possible molecular component of the beta-cell fuel sensor

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12 December 2020

Activation of neutrophil calcium-dependent and -independent phospholipases A2 by organochlorine compounds

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12 December 2020

Studies of insulin secretory responses and of arachidonic acid incorporation into phospholipids of stably transfected insulinoma cells that overexpress group VIA phospholipase A2 (iPLA2beta ) indicate a signaling rather than a housekeeping role for

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12 December 2020

10.1016/J.BBALIP.2010.01.006

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132906%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20132906%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference