Molecular pharmacology of the CFTR Cl- channel (Q33763425)

29 July 2017

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title

Molecular pharmacology of the CFTR Cl- channel (English)

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29 July 2017

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Hwang TC

1

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PubMed ID

10542444

29 July 2017

Sheppard DN

series ordinal

2

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29 July 2017

1 November 1999

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Trends in Pharmacological Sciences

29 July 2017

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29 July 2017

20

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29 July 2017

11

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29 July 2017

448-453

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Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

29 July 2017

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https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Structure and function of the CFTR chloride channel

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https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

The CFTR chloride channel of mammalian heart

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Epithelial transport in polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Pharmacology of CFTR chloride channel activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Status of gene therapy for cystic fibrosis lung disease

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Novel pharmacologic therapies for cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Chloride Conductance Expressed by ΔF508 and Other Mutant CFTRs In Xenopus Oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Phosphatase inhibitors activate normal and defective CFTR chloride channels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Cystic fibrosis transmembrane conductance regulator activation by cAMP-independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Activation of wild-type and deltaF508-CFTR by phosphodiesterase inhibitors through cAMP-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Direct activation of cystic fibrosis transmembrane conductance regulator channels by 8-cyclopentyl-1,3-dipropylxanthine (CPX) and 1,3-diallyl-8-cyclohexylxanthine (DAX).

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

8-cyclopentyl-1,3-dipropylxanthine and other xanthines differentially bind to the wild-type and delta F508 first nucleotide binding fold (NBF-1) domains of the cystic fibrosis transmembrane conductance regulator

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Structural basis for specificity and potency of xanthine derivatives as activators of the CFTR chloride channel.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Modulation of CFTR chloride channels by calyculin A and genistein

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

CFTR chloride channel activation by genistein: the role of serine/threonine protein phosphatases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Genistein activates CFTR Cl- channels via a tyrosine kinase- and protein phosphatase-independent mechanism

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https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Genistein potentiates wild-type and delta F508-CFTR channel activity

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https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Direct action of genistein on CFTR.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Synergistic activation of guinea-pig cardiac cystic fibrosis transmembrane conductance regulator by the tyrosine kinase inhibitor genistein and cAMP

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Actions of genistein on cystic fibrosis transmembrane conductance regulator channel gating. Evidence for two binding sites with opposite effects

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Inhibition of ATPase, GTPase and adenylate kinase activities of the second nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator by genistein.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Diphenylamine-2-carboxylate, a blocker of the Cl(-)-conductive pathway in Cl(-)-transporting epithelia.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Cl(-)-channel blockers in the thick ascending limb of the loop of Henle. Structure activity relationship

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Voltage-dependent block of the cystic fibrosis transmembrane conductance regulator Cl- channel by two closely related arylaminobenzoates

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Novel pore-lining residues in CFTR that govern permeation and open-channel block

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Arylaminobenzoate block of the cardiac cyclic AMP-dependent chloride current.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Structural and ionic determinants of 5-nitro-2-(3-phenylprophyl-amino)-benzoic acid block of the CFTR chloride channel

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Sulfonylurea receptors and mechanism of sulfonylurea action

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Correlating structure and function in ATP-sensitive K+ channels.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Effect of ATP-sensitive K+ channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Cl- channel inhibition by glibenclamide is not specific for the CFTR-type Cl- channel

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Inhibitory effects of glibenclamide on cystic fibrosis transmembrane regulator, swelling-activated, and Ca(2+)-activated Cl- channels in mammalian cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Mechanism of glibenclamide inhibition of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a murine cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Tolbutamide causes open channel blockade of cystic fibrosis transmembrane conductance regulator Cl- channels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Identification of cystic fibrosis transmembrane conductance regulator channel-lining residues in and flanking the M6 membrane-spanning segment.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Permeability of wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels to polyatomic anions

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Disulphonic stilbene block of cystic fibrosis transmembrane conductance regulator Cl- channels expressed in a mammalian cell line and its regulation by a critical pore residue

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Flickery block of single CFTR chloride channels by intracellular anions and osmolytes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

The inward rectifier potassium channel family.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Substrates of multidrug resistance-associated proteins block the cystic fibrosis transmembrane conductance regulator chloride channel

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

Protein phosphatase 2C dephosphorylates and inactivates cystic fibrosis transmembrane conductance regulator

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2899%2901386-3

7 January 2021

10.1016/S0165-6147(99)01386-3

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10542444