Effect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems (Q33753725)

29 July 2017

title

Effect of calcium-sensitizing mutations on calcium binding and exchange with troponin C in increasingly complex biochemical systems (English)

1 reference

29 July 2017

Svetlana B Tikunova

1

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29 July 2017

Bin Liu

2

1 reference

29 July 2017

Nicholas Swindle

3

1 reference

29 July 2017

Sean C Little

4

1 reference

29 July 2017

Aldrin V Gomes

5

1 reference

29 July 2017

Darl R Swartz

6

1 reference

29 July 2017

Jonathan P Davis

7

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29 July 2017

language of work or name

English

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publication date

1 March 2010

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29 July 2017

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29 July 2017

volume

49

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29 July 2017

issue

9

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29 July 2017

page(s)

1975-1984

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A functional and structural study of troponin C mutations related to hypertrophic cardiomyopathy.

29 July 2017

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28 July 2018

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Ca(2+) exchange with troponin C and cardiac muscle dynamics

28 July 2018

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Effects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin C

28 July 2018

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Calcium, thin filaments, and the integrative biology of cardiac contractility

28 July 2018

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Molecular and cellular aspects of troponin cardiomyopathies

28 July 2018

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Covalent and noncovalent modification of thin filament action: the essential role of troponin in cardiac muscle regulation.

28 July 2018

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Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form

28 July 2018

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28 July 2018

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Skeletal and cardiac muscle contractile activation: tropomyosin "rocks and rolls".

28 July 2018

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28 July 2018

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28 July 2018

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Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-C

28 July 2018

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Calcium-induced structural transition in the regulatory domain of human cardiac troponin C

28 July 2018

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Thin filament-mediated regulation of cardiac contraction

28 July 2018

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The effects of N helix deletion and mutant F29W on the Ca2+ binding and functional properties of chicken skeletal muscle troponin

28 July 2018

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The troponin complex and regulation of muscle contraction

28 July 2018

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28 July 2018

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A fluorescent probe study of Ca2+ binding to the Ca2+-specific sites of cardiac troponin and troponin C

28 July 2018

1 reference

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Cooperative binding to the Ca2+-specific sites of troponin C in regulated actin and actomyosin.

28 July 2018

1 reference

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Calcium- and myosin-dependent changes in troponin structure during activation of heart muscle.

28 July 2018

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Challenging current paradigms related to cardiomyopathies. Are changes in the Ca2+ sensitivity of myofilaments containing cardiac troponin C mutations (G159D and L29Q) good predictors of the phenotypic outcomes?

30 October 2018

1 reference

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Intramolecular interactions in the N-domain of cardiac troponin C are important determinants of calcium sensitivity of force development

30 October 2018

1 reference

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Structural based insights into the role of troponin in cardiac muscle pathophysiology

30 October 2018

1 reference

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Cardiac troponin T isoforms affect the Ca(2+) sensitivity of force development in the presence of slow skeletal troponin I: insights into the role of troponin T isoforms in the fetal heart.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845643

Designing calcium-sensitizing mutations in the regulatory domain of cardiac troponin C.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845643

Mutations of hydrophobic residues in the N-terminal domain of troponin C affect calcium binding and exchange with the troponin C-troponin I96-148 complex and muscle force production.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845643

Engineering competitive magnesium binding into the first EF-hand of skeletal troponin C.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845643

Effect of hydrophobic residue substitutions with glutamine on Ca(2+) binding and exchange with the N-domain of troponin C.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845643

Conformation of the regulatory domain of cardiac muscle troponin C in its complex with cardiac troponin I.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845643

E. coli expression and characterization of a mutant troponin I with the three cysteine residues substituted.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845643

Mutagenesis of cardiac troponin I. Role of the unique NH2-terminal peptide in myofilament activation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2845643

The calcium and magnesium binding sites on cardiac troponin and their role in the regulation of myofibrillar adenosine triphosphatase

30 October 2018

1 reference

12 December 2020

Calcium binds cooperatively to the regulatory sites of the cardiac thin filament

1 reference

12 December 2020

Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin I

1 reference

12 December 2020

Modulation of the rate of cardiac muscle contraction by troponin C constructs with various calcium binding affinities

1 reference

12 December 2020

Identifiers

DOI

10.1021/BI901867S

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29 July 2017

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29 July 2017

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