Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cells (Q33749295)

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English	Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cells	scientific article

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18 January 2020

Mixed Lineage Kinase 3 deficiency delays viral clearance in the lung and is associated with diminished influenza-induced cytopathic effect in infected cells (English)

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18 January 2020

Stephen Dewhurst

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18 January 2020

Sanjay B Maggirwar

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Sanjay B Maggirwar

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18 January 2020

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Emily A Desmet

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18 January 2020

Joseph A Hollenbaugh

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18 January 2020

Patricia J Sime

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18 January 2020

Terry W Wright

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18 January 2020

David J Topham

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18 January 2020

Andrea J Sant

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18 January 2020

Toru Takimoto

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18 January 2020

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25 February 2010

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18 January 2020

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18 January 2020

400

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18 January 2020

2

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18 January 2020

224-232

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18 January 2020

Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes

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21 June 2018

Infection of HLA-DR1 transgenic mice with a human isolate of influenza a virus (H1N1) primes a diverse CD4 T-cell repertoire that includes CD4 T cells with heterosubtypic cross-reactivity to avian (H5N1) influenza virus.

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21 June 2018

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

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21 June 2018

H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice.

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21 June 2018

Pathology, molecular biology, and pathogenesis of avian influenza A (H5N1) infection in humans

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21 June 2018

Influenza A virus PB1-F2: a small protein with a big punch.

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21 June 2018

Mixed lineage kinase 3 connects reactive oxygen species to c-Jun NH2-terminal kinase-induced mitochondrial apoptosis in genipin-treated PC3 human prostate cancer cells

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21 June 2018

The annual impact of seasonal influenza in the US: Measuring disease burden and costs

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21 June 2018

Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza virus hemagglutinin

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21 June 2018

Mixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity?

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21 June 2018

Down-regulation Cdc42 attenuates neuronal apoptosis through inhibiting MLK3/JNK3 cascade during ischemic reperfusion in rat hippocampus

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21 June 2018

Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus

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21 June 2018

Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA

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21 June 2018

Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells

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21 June 2018

Role of apoptosis and cytokines in influenza virus morbidity

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21 June 2018

Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades

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21 June 2018

Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus.

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21 June 2018

MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation

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21 June 2018

Mixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cells

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21 June 2018

An early CD4+ T cell-dependent immunoglobulin A response to influenza infection in the absence of key cognate T-B interactions

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21 June 2018

Mixed-lineage kinase control of JNK and p38 MAPK pathways

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21 June 2018

Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway

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21 June 2018

Evidence for a role of mixed lineage kinases in neuronal apoptosis

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21 June 2018

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis

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21 June 2018

c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation

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21 June 2018

JNK is required for effector T-cell function but not for T-cell activation

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21 June 2018

p38 mitogen-activated protein kinase and c-jun-NH2-terminal kinase regulate RANTES production by influenza virus-infected human bronchial epithelial cells

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21 June 2018

Activation of p38 mitogen-activated protein kinase in vivo selectively induces apoptosis of CD8(+) but not CD4(+) T cells

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21 June 2018

Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

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21 June 2018

MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6

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30 October 2018

Early intrahepatic accumulation of CD8+ T cells provides a source of effectors for nonhepatic immune responses.

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30 October 2018

Inhibition of mixed lineage kinase 3 prevents HIV-1 Tat-mediated neurotoxicity and monocyte activation.

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30 October 2018

Differential induction of apoptosis by cigarette smoke extract in primary human lung fibroblast strains: implications for emphysema.

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30 October 2018

Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

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30 October 2018

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30 October 2018

Expression and function of mixed lineage kinases in dendritic cells

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7 January 2021

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

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7 January 2021

CD4 T cell-independent antibody response promotes resolution of primary influenza infection and helps to prevent reinfection

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7 January 2021

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Recovery from a viral respiratory infection. I. Influenza pneumonia in normal and T-deficient mice

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12 December 2020

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Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20185156

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/J.VIROL.2010.02.001

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Europe PubMed Central

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18 January 2020

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18 January 2020

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18 January 2020

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