Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs (Q33748142)

29 July 2017

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title

Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs (English)

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29 July 2017

Serajuddin AT

1

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PubMed ID

10514356

29 July 2017

language of work or name

English

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publication date

1 October 1999

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Journal of Pharmaceutical Sciences

29 July 2017

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29 July 2017

88

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29 July 2017

10

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29 July 2017

1058-1066

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Pharmaceutical Applications of Solid Dispersion Systems

29 July 2017

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7 January 2021

Preparation and Dissolution Characteristics of Several Fast-Release Solid Dispersions of Griseofulvin

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7 January 2021

Preparation and properties of solid dispersion system containing citric acid and primidone

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7 January 2021

Dissolution rates of corticosteroids utilizing sugar glass dispersions

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7 January 2021

Thermal Characterization of Citric Acid Solid Dispersions with Benzoic Acid and Phenobarbital

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7 January 2021

Comparative dissolution studies for mefenamic acid-polyethylene glycol solid dispersion systems and tablets

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7 January 2021

Dissolution Rates of High Energy Polyvinylpyrrolidone (PVP)-Sulfathiazole Coprecipitates

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7 January 2021

Solid dispersion approach for overcoming bioavailability problems due to polymorphism of nabilone, a cannabinoid derivative

1 reference

7 January 2021

Amorphous spray-dried hydroflumethiazide-polyvinylpyrrolidone systems: physiochemical properties

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7 January 2021

Oral absorption improvement of poorly soluble drug using solid dispersion technique

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7 January 2021

Crystallinity and dissolution rate of tolbutamide solid dispersions prepared by the melt method

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7 January 2021

Physical stability of solid dispersions containing triamterene or temazepam in polyethylene glycols

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7 January 2021

Comparison of polyethylene glycol and polyoxyethylene stearate as excipients for solid dispersion systems of griseofulvin and tolbutamide II: dissolution and solubility studies

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7 January 2021

Particle size dependency of dissolution rate and human bioavailability of phenytoin in powders and phenytoin-polyethylene glycol solid dispersions

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7 January 2021

Development and optimization of a solid dispersion hot-melt fluid bed coating method

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7 January 2021

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7 January 2021

Pharmaceutical applications of solid dispersion systems: X-ray diffraction and aqueous solubility studies on griseofulvin-polyethylene glycol 6000 systems

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7 January 2021

Characteristics and significance of the amorphous state in pharmaceutical systems

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7 January 2021

Effects of sorbed water on the crystallization of indomethacin from the amorphous state

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7 January 2021

Spectroscopic characterization of interactions between PVP and indomethacin in amorphous molecular dispersions.

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7 January 2021

Phase behavior of binary and ternary amorphous mixtures containing indomethacin, citric acid, and PVP

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7 January 2021

Effect of Vehicle Amphiphilicity on the Dissolution and Bioavailability of a Poorly Water-Soluble Drug from Solid Dispersions

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7 January 2021

Improved dissolution of a poorly water-soluble drug from solid dispersions in polyethylene glycol: polysorbate 80 mixtures

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7 January 2021

Physicochemical Basis of Increased Bioavailability of a Poorly Water-Soluble Drug following Oral Administration as Organic Solutions

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7 January 2021

Evaluation of emulsifiable glasses for the oral administration of cyclosporin in beagle dogs

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7 January 2021

Solid surfactant solutions of active ingredients in sugar esters

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7 January 2021

Structural properties of polyethylene glycol-polysorbate 80 mixture, a solid dispersion vehicle

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7 January 2021

Water migration from soft gelatin capsule shell to fill material and its effect on drug solubility

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7 January 2021

Bioavailability of a poorly water-soluble drug from tablet and solid dispersion in humans

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7 January 2021

An investigation into the effects of preparation conditions and storage on the rate of drug release from pharmaceutical glyceride bases

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7 January 2021

Solidification studies of polyethylene glycols, gelucire 44/14 or their dispersions with triamterene or temazepam

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7 January 2021

Identifiers

DOI

10.1021/JS980403L

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29 July 2017

1 reference

PubMed ID

10514356