G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling (Q33743722)

29 July 2017

G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling (English)

1 reference

29 July 2017

Haixia Gong

1

1 reference

29 July 2017

Bo Shen

2

1 reference

29 July 2017

Panagiotis Flevaris

3

1 reference

29 July 2017

Christina Chow

4

1 reference

29 July 2017

Stephen C-T Lam

5

1 reference

29 July 2017

Tatyana A Voyno-Yasenetskaya

6

1 reference

29 July 2017

Tohru Kozasa

7

1 reference

29 July 2017

Xiaoping Du

8

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29 July 2017

language of work or name

English

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publication date

1 January 2010

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29 July 2017

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29 July 2017

327

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29 July 2017

5963

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29 July 2017

340-343

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Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Platelet integrin alpha(IIb)beta(3): activation mechanisms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Integrin signalling in directed cell migration.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Integrins and Src: dynamic duo of adhesion signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Receptors coupled to heterotrimeric G proteins of the G12 family

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Regulation of RGS-RhoGEFs by Galpha12 and Galpha13 proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Integrins: bidirectional, allosteric signaling machines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression model

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

GTP-binding proteins and platelet activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2842917

Src kinase activation by direct interaction with the integrin β cytoplasmic domain

28 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174779

A molecular switch that controls cell spreading and retraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174779

Consistent up-regulation of Stat3 Independently of Jak2 mutations in a new murine model of essential thrombocythemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174779

Cdc42/Rac1-dependent activation of the p21-activated kinase (PAK) regulates human platelet lamellipodia spreading: implication of the cortical-actin binding protein cortactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1174779

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

21 January 2018

1 reference

12 December 2020

Determination of GTP loading on Rho

1 reference

12 December 2020

Interaction of normal, thrombasthenic, and Bernard-Soulier platelets with immobilized fibrinogen: defective platelet-fibrinogen interaction in thrombasthenia

1 reference

12 December 2020

Signaling through G(alpha)13 switch region I is essential for protease-activated receptor 1-mediated human platelet shape change, aggregation, and secretion

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIENCE.1174779

1 reference

29 July 2017

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29 July 2017

1 reference