Peptides, enzymes and obesity: new insights from a 'dead' enzyme (Q33740220)

29 July 2017

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title

Peptides, enzymes and obesity: new insights from a 'dead' enzyme (English)

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29 July 2017

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Fricker LD

1

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PubMed ID

10500303

29 July 2017

Leiter EH

series ordinal

2

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PubMed ID

10500303

29 July 2017

language of work or name

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1 October 1999

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29 July 2017

4

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Trends in Biochemical Sciences

inferred from page(s)

published in

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29 July 2017

24

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29 July 2017

10

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29 July 2017

390-393

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Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Enkephalin convertase: purification and characterization of a specific enkephalin-synthesizing carboxypeptidase localized to adrenal chromaffin granules

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

1 reference

7 January 2021

Peptide alpha-amidation

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Induced and spontaneous mutations at Ser202 of carboxypeptidase E. Effect on enzyme expression, activity, and intracellular routing

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Carboxypeptidase E activity is deficient in mice with the fat mutation. Effect on peptide processing.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Impaired processing of brain proneurotensin and promelanin-concentrating hormone in obese fat/fat mice

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Identification of mouse CPX-1, a novel member of the metallocarboxypeptidase gene family with highest similarity to CPX-2

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Identification of mouse CPX-2, a novel member of the metallocarboxypeptidase gene family: cDNA cloning, mRNA distribution, and protein expression and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

A eukaryotic transcriptional repressor with carboxypeptidase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Cloning and expression of human carboxypeptidase Z, a novel metallocarboxypeptidase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Purification and characterization of carboxypeptidase D, a novel carboxypeptidase E-like enzyme, from bovine pituitary

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Cloning, sequence analysis, and distribution of rat metallocarboxypeptidase Z.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

gp180, a protein that binds duck hepatitis B virus particles, has metallocarboxypeptidase D-like enzymatic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

gp180, a host cell glycoprotein that binds duck hepatitis B virus particles, is encoded by a member of the carboxypeptidase gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Cloning and sequence analysis of cDNA encoding rat carboxypeptidase D.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Sequence of human carboxypeptidase D reveals it to be a member of the regulatory carboxypeptidase family with three tandem active site domains

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Tissue distribution and characterization of soluble and membrane-bound forms of metallocarboxypeptidase D.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Carboxypeptidase D is a potential candidate to carry out redundant processing functions of carboxypeptidase E based on comparative distribution studies in the rat central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Biosynthesis and packaging of carboxypeptidase D into nascent secretory vesicles in pituitary cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Localization of metallocarboxypeptidase D in AtT-20 cells. Potential role in prohormone processing.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Physiologic and endocrinologic characterization of male sex-biased diabetes in C57BLKS/J mice congenic for the fat mutation at the carboxypeptidease E locus

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Beta-cell lines derived from transgenic Cpe(fat)/Cpe(fat) mice are defective in carboxypeptidase E and proinsulin processing

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E-deficient Cpefat/Cpefat mice

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Organization of the human carboxypeptidase E gene and molecular scanning for mutations in Japanese subjects with NIDDM or obesity

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Glycoproteins of the aspartyl proteinase gene family secreted by the developing placenta.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Metalloprotease-disintegrins: links to cell adhesion and cleavage of TNF alpha and Notch

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Congenital leptin deficiency is associated with severe early-onset obesity in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Molecular characterization of the mouse agouti locus.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Positional cloning of the mouse obese gene and its human homologue

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

A candidate gene for the mouse mutation tubby

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2899%2901448-6

7 January 2021

10.1016/S0968-0004(99)01448-6

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10500303