The antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathway (Q33740186)

29 July 2017

The antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathway (English)

1 reference

29 July 2017

1 reference

Iqbal Dulloo

1

1 reference

29 July 2017

Ganesan Gopalan

series ordinal

2

1 reference

29 July 2017

Gerry Melino

series ordinal

3

1 reference

29 July 2017

Kanaga Sabapathy

series ordinal

4

1 reference

29 July 2017

language of work or name

English

0 references

publication date

25 February 2010

1 reference

29 July 2017

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

29 July 2017

107

1 reference

29 July 2017

11

1 reference

29 July 2017

4902-4907

1 reference

Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics.

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Antizyme inhibitor: mysterious modulator of cell proliferation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

c-Jun promotes cellular survival by suppression of PTEN.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

UFD2a mediates the proteasomal turnover of p73 without promoting p73 ubiquitination

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Calpain cleavage regulates the protein stability of p73.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Regulation of the p73 protein stability and degradation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

The ubiquitin-protein ligase Itch regulates p73 stability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Multiple stress signals induce p73beta accumulation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

c-Jun regulates the stability and activity of the p53 homologue, p73.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Antizyme targets cyclin D1 for degradation. A novel mechanism for cell growth repression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

DNA damage induces the rapid and selective degradation of the DeltaNp73 isoform, allowing apoptosis to occur

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

AP-1: a double-edged sword in tumorigenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Antizyme overexpression in transgenic mice reduces cell proliferation, increases apoptosis, and reduces N-nitrosomethylbenzylamine-induced forestomach carcinogenesis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

p73: Friend or foe in tumorigenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs).

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Possible oncogenic potential of DeltaNp73: a newly identified isoform of human p73

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Regulation of cellular polyamines by antizyme

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Overproduction of stable ornithine decarboxylase and antizyme in the difluoromethylornithine-resistant cell line DH23b

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2841924

Regulation of ornithine decarboxylase

14 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906782107

Antizyme1 mediates AURKAIP1-dependent degradation of Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906782107

Yes-Associated Protein (YAP) is a critical mediator of c-Jun-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906782107

DNp73α protects myogenic cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0906782107

Modulation of p53 and p73 levels by cyclin G: implication of a negative feedback regulation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20185758

12 December 2020

inferred from PubMed ID database lookup

Chemosensitivity linked to p73 function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20185758

12 December 2020

inferred from PubMed ID database lookup

c-Abl stabilizes p73 by a phosphorylation-augmented interaction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20185758

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0906782107

1 reference

release_em65lth4qfbp5mrktfzhrkytau

29 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/em65lth4qfbp5mrktfzhrkytau

24 November 2022

mapped directly with Wikidata item

PMCID

2841924

1 reference

29 July 2017

1 reference