Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP). (Q33737486)

29 July 2017

Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP). (English)

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29 July 2017

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acute myeloid leukemia

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9

Wendy J Fantl

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29 July 2017

David B Rosen

1

1 reference

29 July 2017

Mark D Minden

2

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29 July 2017

Steven M Kornblau

3

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29 July 2017

Aileen Cohen

4

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29 July 2017

Urte Gayko

5

1 reference

29 July 2017

Santosh Putta

6

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29 July 2017

John Woronicz

7

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29 July 2017

Erik Evensen

8

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29 July 2017

Alessandra Cesano

10

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29 July 2017

language of work or name

English

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publication date

27 October 2010

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29 July 2017

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29 July 2017

5

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29 July 2017

e13543

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29 July 2017

10

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Creative Commons Attribution 4.0 International

29 July 2017

start time

27 October 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Size of FLT3 internal tandem duplication has prognostic significance in patients with acute myeloid leukemia

21 June 2018

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No evidence that FLT3 status should be considered as an indicator for transplantation in acute myeloid leukemia (AML): an analysis of 1135 patients, excluding acute promyelocytic leukemia, from the UK MRC AML10 and 12 trials.

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Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype

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Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations

21 June 2018

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Causal protein-signaling networks derived from multiparameter single-cell data

21 June 2018

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AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations.

21 June 2018

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Molecular heterogeneity and prognostic biomarkers in adults with acute myeloid leukemia and normal cytogenetics

21 June 2018

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Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis

21 June 2018

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Extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways cooperate in mediating cytokine-induced proliferation of a leukemic cell line

21 June 2018

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Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study.

21 June 2018

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The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

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Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

21 June 2018

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Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia

21 June 2018

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Flt3 ligand induces tyrosine phosphorylation of gab1 and gab2 and their association with shp-2, grb2, and PI3 kinase

21 June 2018

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Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells

21 June 2018

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FLT3 signaling in hematopoietic cells involves CBL, SHC and an unknown P115 as prominent tyrosine-phosphorylated substrates

21 June 2018

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21 June 2018

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Mitogenic signalling and substrate specificity of the Flk2/Flt3 receptor tyrosine kinase in fibroblasts and interleukin 3-dependent hematopoietic cells

21 June 2018

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The meaning and use of the area under a receiver operating characteristic (ROC) curve

21 June 2018

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A method of comparing the areas under receiver operating characteristic curves derived from the same cases

21 June 2018

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Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm.

21 June 2018

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FLT3 mutation and response to intensive chemotherapy in young adult and elderly patients with normal karyotype.

21 January 2018

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BAALC expression and FLT3 internal tandem duplication mutations in acute myeloid leukemia patients with normal cytogenetics: prognostic implications.

21 January 2018

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Prognostic significance of CEBPA mutations in a large cohort of younger adult patients with acute myeloid leukemia: impact of double CEBPA mutations and the interaction with FLT3 and NPM1 mutations.

21 January 2018

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AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations.

21 January 2018

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FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model

21 January 2018

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Mapping normal and cancer cell signalling networks: towards single-cell proteomics

21 January 2018

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Human Flt3 is expressed at the hematopoietic stem cell and the granulocyte/macrophage progenitor stages to maintain cell survival

21 January 2018

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Interleukin-27 directly induces differentiation in hematopoietic stem cells

21 January 2018

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Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations.

21 January 2018

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ABCB1 and ABCG2 proteins, their functional activity and gene expression in concert with drug sensitivity of leukemia cells.

21 January 2018

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Robust Tests for the Equality of Variances

21 January 2018

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Incidence and prognostic value of FLT3 internal tandem duplication and D835 mutations in acute myeloid leukemia

21 January 2018

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Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways.

30 October 2018

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Expression and Signal Transduction of the FLT3 Tyrosine Kinase Receptor

30 October 2018

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Prognostic significance of FLT3 ITD and D835 mutations in AML patients

21 January 2018

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12 December 2020

Prognostic value of internal tandem duplication of the FLT3 gene in childhood acute myelogenous leukemia

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12 December 2020

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

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12 December 2020

The FLT3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34+ bone marrow progenitor cells in vitro

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12 December 2020

Flt3 ligand induces proliferation of quiescent human bone marrow CD34+CD38- cells and maintains progenitor cells in vitro

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12 December 2020

IL-4, IL-10 and IL-13 in acute myelogenous leukemia

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12 December 2020

Internal tandem duplication of the FLT3 gene and clinical evaluation in childhood acute myeloid leukemia. The Children's Cancer and Leukemia Study Group, Japan

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12 December 2020

Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia

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12 December 2020

Tyrosine kinases as targets for cancer therapy

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12 December 2020

Expression of pSTAT5 predicts FLT3 internal tandem duplications in acute myeloid leukemia

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12 December 2020

10.1371/JOURNAL.PONE.0013543

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DOI

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29 July 2017

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29 July 2017

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