IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection (Q33733943)

29 July 2017

IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection (English)

1 reference

29 July 2017

David G Brooks

1

1 reference

29 July 2017

Kevin B Walsh

series ordinal

2

1 reference

29 July 2017

Heidi Elsaesser

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3

1 reference

29 July 2017

Michael B A Oldstone

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4

1 reference

29 July 2017

language of work or name

English

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publication date

26 January 2010

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

1 reference

29 July 2017

107

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29 July 2017

7

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29 July 2017

3018-3023

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A vital role for interleukin-21 in the control of a chronic viral infection

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

IL-21 is required to control chronic viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Effector and memory CTL differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Interleukin-10 determines viral clearance or persistence in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Resolution of a chronic viral infection after interleukin-10 receptor blockade

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Cooperation between CD4+ and CD8+ T cells: when, where, and how.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Early impairment of hepatitis C virus specific T cell proliferation during acute infection leads to failure of viral clearance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Restoring function in exhausted CD8 T cells during chronic viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Initial T cell frequency dictates memory CD8+ T cell lineage commitment

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Determinants of viral clearance and persistence during acute hepatitis C virus infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Interleukin-10 and the interleukin-10 receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Homeostasis of naive and memory T cells

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

Molecular and functional profiling of memory CD8 T cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

The two faces of interleukin 10 in human infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

Defective dendritic cell function in HIV-infected patients receiving effective highly active antiretroviral therapy: neutralization of IL-10 production and depletion of CD4+CD25+ T cells restore high levels of HIV-specific CD4+ T cell responses indu

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

IL-10 is required for optimal CD8 T cell memory following Listeria monocytogenes infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

Blocking of interleukin-10 receptor--a novel approach to stimulate T-helper cell type 1 responses to hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

Precursor frequency, nonlinear proliferation, and functional maturation of virus-specific CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

Therapeutic dendritic-cell vaccine for chronic HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

IL-21R on T cells is critical for sustained functionality and control of chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0914500107

Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

The duration of antigenic stimulation determines the fate of naive and effector T cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

Immunoregulatory cytokines in chronic hepatitis C virus infection: pre- and posttreatment with interferon alfa

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2840337

The interplay between the duration of TCR and cytokine signaling determines T cell polarization

30 October 2018

1 reference

12 December 2020

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

1 reference

12 December 2020

Induction of tolerance by IL-10-treated dendritic cells

1 reference

12 December 2020

Priming in the presence of IL-10 results in direct enhancement of CD8+ T cell primary responses and inhibition of secondary responses

1 reference

12 December 2020

Direct interferon-gamma signaling dramatically enhances CD4+ and CD8+ T cell memory

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0914500107

1 reference

29 July 2017

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1 reference

29 July 2017

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