Molecular mechanisms of actions of interleukin-6 on the brain, with special reference to serotonin and the hypothalamo-pituitary-adrenocortical axis (Q33732289)

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English	Molecular mechanisms of actions of interleukin-6 on the brain, with special reference to serotonin and the hypothalamo-pituitary-adrenocortical axis	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

Molecular mechanisms of actions of interleukin-6 on the brain, with special reference to serotonin and the hypothalamo-pituitary-adrenocortical axis (English)

1 reference

Europe PubMed Central

29 July 2017

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author name string

Barkhudaryan N

1

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Europe PubMed Central

29 July 2017

Dunn AJ

2

1 reference

Europe PubMed Central

29 July 2017

publication date

1 September 1999

1 reference

Europe PubMed Central

29 July 2017

Neurochemical Research

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Europe PubMed Central

29 July 2017

24

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Europe PubMed Central

29 July 2017

9

1 reference

Europe PubMed Central

29 July 2017

1169-1180

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Europe PubMed Central

29 July 2017

https://scigraph.springernature.com/pub.10.1023/a:1020720722209

0 references

Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic roles of interleukin-6, interleukin-1, and tumor necrosis factor in the adrenocorticotropin response to bacterial lipopolysaccharide in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of interleukin-1 receptors in the brain-endocrine-immune axis by stress and infection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CRF-deficient mice respond like wild-type mice to hypophagic stimuli.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major role of 3',5'-cyclic adenosine monophosphate-dependent protein kinase A pathway in corticotropin-releasing factor gene expression in the rat hypothalamus in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

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The role of cytokines in the behavioral responses to endotoxin and influenza virus infection in mice: effects of acute and chronic administration of the interleukin-1-receptor antagonist (IL-1ra).

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction pathways mediating astrocyte IL-6 induction by IL-1 beta and tumor necrosis factor-alpha.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mouse interleukin-6 stimulates the HPA axis and increases brain tryptophan and serotonin metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of opioids on the hypothalamo-pituitary-adrenal axis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune-neuro-endocrine interactions: facts and hypotheses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of 5-HT1A receptor subtype in the paraventricular nuclei of the hypothalamus induces CRH and ACTH release in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of interleukin 6 (interferon-beta 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of brown fat thermogenesis in response to central injection of corticotropin releasing hormone in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-endorphin modulation of IL-1-induced IL-2 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for an immune response in major depression: a review and hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines in the central nervous system: regulatory roles in neuronal function, cell death and repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological basis of the behavior of sick animals

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heatstroke-induced cerebral ischemia and neuronal damage. Involvement of cytokines and monoamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific increase in norepinephrine turnover by central interleukin-1, but not by interleukin-6, in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine-induced anorexia. Behavioral, cellular, and molecular mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similarity of neuronal cell injury and death in AIDS dementia and focal cerebral ischemia: potential treatment with NMDA open-channel blockers and nitric oxide-related species

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of hypothalamic serotonin in activation of the sympathoadrenomedullary system and hypothalamo-pituitary-adrenocortical axis in male Wistar rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multifactorial nature of human immunodeficiency virus disease: implications for therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 knock-out mice show modified basal immune functions, but normal immune responses to stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1-induced IL-8 and IL-6 gene expression and production in human mesangial cells is differentially regulated by cAMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of IL6 gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine regulation of embryonic rat dopamine and serotonin neuronal survival in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of hypothalamic interleukin-6 and tumor necrosis factor-alpha in LPS fever in rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of corticotropin-releasing factor on brain serotonergic activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine A2b receptors mediate an increase in interleukin (IL)-6 mRNA and IL-6 protein synthesis in human astroglioma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase A-dependent IL-6 production induced by calcitonin in human glioblastoma A172 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurons containing beta-endorphin in rat brain exist separately from those containing enkephalin: immunocytochemical studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of striatal prodynorphin mRNA levels by the raphe-striatal pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fenfluramine, p-chloroamphetamine and p-fluoroamphetamine stimulation of pituitary-adrenocortical activity in rat: evidence for differences in site and mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticotropin-releasing factor administration elicits a stress-like activation of cerebral catecholaminergic systems.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of tumor necrosis factor alpha (TNF alpha) and interleukin 6 (IL-6) mRNA in adult human astrocytes: comparison with adult microglia and fetal astrocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indomethacin prevents increased catecholamine turnover in rat brain following systemic endotoxin challenge.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat hypothalamus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticotropin-releasing factor in antinociception and inflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum interleukin-6 concentration in schizophrenia: elevation associated with duration of illness

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dorsal raphe: an important nucleus in pain modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of interleukin-6 in the activation of the hypothalamo-pituitary-adrenocortical axis and brain indoleamines by endotoxin and interleukin-1 beta.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta uses common and distinct signaling pathways for induction of the interleukin-6 and tumor necrosis factor alpha genes in the human astrocytoma cell line U373.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central administration of rat IL-6 induces HPA activation and fever but not sickness behavior in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin derivative, N-(p-coumaroyl) serotonin, inhibits the production of TNF-alpha, IL-1alpha, IL-1beta, and IL-6 by endotoxin-stimulated human blood monocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear opioid receptors activate opioid peptide gene transcription in isolated myocardial nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro production of IL-6, IL-1 beta, and tumor necrosis factor-alpha by human embryonic microglial and neural cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin and the pharmacology of eating disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of evidence for a role of serotonin in interleukin-1-induced hypophagia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine indices in Alzheimer's temporal cortex: no changes in mature IL-1 beta or IL-1RA but increases in the associated acute phase proteins IL-6, alpha 2-macroglobulin and C-reactive protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presynaptic inhibitory action of opioids on synaptic transmission in the rat periaqueductal grey in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective facilitation of putative corticotropin-releasing factor-secreting neurones by interleukin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid enhancement of beta 2-interferon/B-cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of interleukin-1 and tumor necrosis factor alpha in the neurochemical and neuroendocrine responses to endotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines and food intake: the relevance of the immune system to the student of ingestive behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of corticotrophin releasing factor (CRF) in the thermogenic and anorexic actions of serotonin (5-HT) and related compounds.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitotoxic cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic interleukin-1 administration stimulates hypothalamic norepinephrine metabolism parallelling the increased plasma corticosterone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticotropin-releasing factor stimulates catecholamine release in hypothalamus and prefrontal cortex in freely moving rats as assessed by microdialysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 an endocrine cytokine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin 6 in fever in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin 1 potentiates the secretion of beta-endorphin induced by secretagogues in a mouse pituitary cell line (AtT-20).

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 as an endogenous pyrogen: induction of prostaglandin E2 in brain but not in peripheral blood mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose effects of recombinant human interleukin-6 on pituitary hormone secretion and energy expenditure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine-specific central monoamine alterations induced by interleukin-1, -2 and -6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Effect of Interleukin-6 on Pituitary Hormone Release in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Participation of opioid and serotoninergic systems in prolactin secretion induced by hypothalamic action of estradiol

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parathyroid hormone (1-34)-mediated interleukin-6 induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional changes in neuropeptide levels after 5,7-dihydroxytryptamine-induced serotonin depletion in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: comparison with interleukin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 stimulates the secretion of adrenocorticotropic hormone in conscious, freely-moving rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 synthesis induced by prostaglandin E2: cross-talk regulation by protein kinase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobiology of corticotropin releasing factor (CRF) receptors and CRF-binding protein: implications for the treatment of CNS disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia/reoxygenation-mediated induction of astrocyte interleukin 6: a paracrine mechanism potentially enhancing neuron survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local infusion of interleukin-6 attenuates the neurotoxic effects of NMDA on rat striatal cholinergic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of different types of stressors on peptide messenger ribonucleic acids in the hypothalamic paraventricular nucleus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of endogenous opioid peptides in fenfluramine anorexia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of cytokines in acute neurodegeneration in the CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CRF is involved in the pyrogenic and thermogenic effects of interleukin 1 beta in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of gap junction coupling in the developing neocortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Models of neuronal injury in AIDS: another role for the NMDA receptor?

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the involvement of the central adrenergic system in interleukin 1-induced adrenocortical response

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect on various putative neurotransmitters on the secretion of corticotrophin-releasing hormone from the rat hypothalamus in vitro-a model of the neurotransmitters involved

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines and the nervous system. I: Expression and recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of the sphingomyelin pathway induces interleukin-6 gene expression in human astrocytoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and its receptor: a paradigm for cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for central and peripheral serotonergic control of corticosterone secretion in the conscious rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The development of morphine tolerance and dependence is associated with translocation of protein kinase C.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine activity in cancer-related anorexia/cachexia: role of megestrol acetate and medroxyprogesterone acetate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-endorphin: cytokine and neuropeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of delta-opioid receptors inhibits neuronal-like calcium channels and distal steps of Ca(2+)-dependent secretion in human small-cell lung carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased plasma and ventricular fluid interleukin-6 levels in patients with head injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of homologous interleukin-1, interleukin-6 and tumor necrosis factor-alpha on the core body temperature of mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 stimulates ACTH release by an indirect action which requires endogenous corticotropin releasing factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opioid effects on 45Ca2+ uptake and glutamate release in rat cerebral cortex in primary culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of cerebral noradrenergic systems in the Fos response to interleukin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin- and interleukin-1-induced hypophagia are not affected by adrenergic, dopaminergic, histaminergic, or muscarinic antagonists.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress- and endotoxin-induced increases in brain tryptophan and serotonin metabolism depend on sympathetic nervous system activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracerebroventricular administration of beta-endorphin increases the expression of c-fos and of corticotropin-releasing factor messenger ribonucleic acid in the paraventricular nucleus of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 is a centrally acting endogenous pyrogen in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6: an overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sickness behavior as a new target for drug development

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 in human multiple myeloma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 induces changes in norepinephrine metabolism in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 selectively enhances the intracellular calcium response to NMDA in developing CNS neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Norepinephrine and vasoactive intestinal peptide induce IL-6 secretion by astrocytes: synergism with IL-1 beta and TNF alpha.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of serotonergic and noradrenergic neurotransmission in the rat hippocampus after peripheral administration of bacterial endotoxin: involvement of the cyclo-oxygenase pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral mechanisms of opioid antinociception in inflammation: involvement of cytokines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is amyloidogenesis during Alzheimer's disease due to an IL-1-/IL-6-mediated 'acute phase response' in the brain?

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of hypothalamic endorphins after repeated injections of anorectics which release serotonin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of corticotropin-releasing factor on the electrical and mechanical activities of the guinea-pig ventricular myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for Brain Corticotropin-Releasing Factor in the Weight-Reducing Effects of Chronic Fenfluramine Treatment in Rats*

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin-6 and transforming growth factor-β in anorexia nervosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the central serotoninergic system in the changes of leu-enkephalin level in discrete rat brain areas

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of bacterial endotoxin and interleukin-1 beta on hippocampal serotonergic neurotransmission, behavioral activity, and free corticosterone levels: an in vivo microdialysis study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in behavior and opioid gene expression induced by the novel tropane analog WF-31.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for serotoninergic system involvement in opioid control of luteinizing hormone secretion in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin receptors and neuroendocrine responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 in biology and medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin administration stimulates cerebral catecholamine release in freely moving rats as assessed by microdialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Species differences in [125I]interleukin-1 binding in brain, endocrine and immune tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin agonists cause parallel activation of the sympathoadrenomedullary system and the hypothalamo-pituitary-adrenocortical axis in conscious rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoregulators in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitatory amino acids and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory mediators in demyelinating disorders of the CNS and PNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of cytokines in infection-induced stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 is pyrogenic but not somnogenic

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-methyl-D-aspartate receptors modulate extracellular 5-hydroxytryptamine concentration in rat hippocampus and striatum in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biological effects of interleukin 6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proenkephalin gene regulation in the neuroendocrine hypothalamus: a model of gene regulation in the CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 and NF-IL6 in acute-phase response and viral infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 5-hydroxytryptamine agonist fenfluramine increases Fos-like immunoreactivity in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential pattern of c-fos mRNA in rat brain following central and systemic administration of interleukin-1-beta: implications for mechanism of action.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of 5-hydroxytryptamine4 receptors causes calcium influx in adrenocortical cells: involvement of calcium in 5-hydroxytryptamine-induced steroid secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enkephalin-immunoreactive neurons in the parvicellular subdivisions of the paraventricular nucleus project to the external zone of the median eminence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virus infection as a stressor: influenza virus elevates plasma concentrations of corticosterone, and brain concentrations of MHPG and tryptophan

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain catecholaminergic and tryptophan responses to restraint are attenuated by nitric oxide synthase inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic and neuroendocrine effects of pro-inflammatory cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune-neuroendocrine circuits: integrative role of cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-Hydroxytryptamine2A receptor stimulation induces activator protein-1 and cyclic AMP-responsive element binding with cyclic AMP-responsive element-binding protein and Jun D as common components in cerebellar neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the serotonin reuptake inhibitor fluoxetine on corticotropin-releasing factor and vasopressin secretion into hypophysial portal blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticotropin-releasing hormone receptor expression and functional coupling in neonatal cardiac myocytes and AT-1 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local administration of recombinant human interleukin-1 beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 activation of FOS proto-oncogene protein in the rat hypothalamus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic endotoxin increases L-tryptophan, 5-hydroxyindoleacetic acid, 3-hydroxykynurenine and quinolinic acid content of mouse cerebral cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A central mechanism is involved in the secretion of ACTH in response to IL-6 in rats: comparison to and interaction with IL-1 beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuroendocrine control of appetite: the role of the endogenous opiates, cholecystokinin, TRH, gamma-amino-butyric-acid and the diazepam receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The acute phase response

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of diet and fenfluramine on thermogenesis in the rat: possible involvement of serotonergic mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Noradrenergic innervation of the hypothalamus participates in adrenocortical responses to interleukin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Arachidonic Acid Cascade Pathways in lnterleukin-6-Stimulated Corticotropin-Releasing Factor Release in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of cyclo-oxygenase and lipoxygenase in the interleukin-1-induced activation of the HPA axis: dependence on the route of injection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10485589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1020720722209

1 reference

Europe PubMed Central

29 July 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

29 July 2017

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