Inferring fitness landscapes by regression produces biased estimates of epistasis. (Q33730568)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

title

Inferring fitness landscapes by regression produces biased estimates of epistasis (English)

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18 March 2020

1

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18 March 2020

2

Joshua B Plotkin

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18 March 2020

language of work or name

English

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publication date

19 May 2014

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Proceedings of the National Academy of Sciences of the United States of America

18 March 2020

published in

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18 March 2020

volume

111

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18 March 2020

issue

22

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18 March 2020

page(s)

E2301-9

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Should evolutionary geneticists worry about higher-order epistasis?

18 March 2020

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

21 June 2018

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Positive epistasis drives the acquisition of multidrug resistance

21 June 2018

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21 June 2018

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Revealing evolutionary pathways by fitness landscape reconstruction

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Perspective: Sign epistasis and genetic constraint on evolutionary trajectories

21 June 2018

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21 June 2018

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The genetic theory of adaptation: a brief history

21 June 2018

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Stochastic tunnels in evolutionary dynamics

21 June 2018

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Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation

21 June 2018

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Evolution by small steps and rugged landscapes in the RNA virus phi6

21 June 2018

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Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations

21 June 2018

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Protein evolution on partially correlated landscapes

21 June 2018

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21 June 2018

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21 June 2018

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Protein evolution on rugged landscapes

21 June 2018

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The NK model of rugged fitness landscapes and its application to maturation of the immune response

21 June 2018

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Environmental change exposes beneficial epistatic interactions in a catalytic RNA.

21 June 2018

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14 July 2018

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Effects of selective neutrality on the evolution of molecular species

21 January 2018

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How Mutational Networks Shape Evolution: Lessons from RNA Models

21 January 2018

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Equally parsimonious pathways through an RNA sequence space are not equally likely.

21 January 2018

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Negative epistasis between beneficial mutations in an evolving bacterial population

21 January 2018

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Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli.

21 January 2018

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Selection biases the prevalence and type of epistasis along adaptive trajectories

21 January 2018

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A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase

21 January 2018

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Random field models for fitness landscapes

21 January 2018

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Exact results for amplitude spectra of fitness landscapes.

21 January 2018

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Epistatic interactions determine the mutational pathways and coexistence of lineages in clonal Escherichia coli populations.

21 January 2018

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Rapid evolutionary escape by large populations from local fitness peaks is likely in nature.

21 January 2018

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Fitness epistasis among 6 biosynthetic loci in the budding yeast Saccharomyces cerevisiae

21 January 2018

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12 December 2020

Modeling genetic architecture: a multilinear theory of gene interaction

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Rapid in vivo exploration of a 5S rRNA neutral network

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12 December 2020

Evolution in a rugged fitness landscape

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1400849111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843135%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

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18 March 2020

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