Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation (Q33730095)

29 July 2017

Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation (English)

1 reference

29 July 2017

1 reference

Sarah L Rowland

1

1 reference

29 July 2017

Corinne L DePersis

series ordinal

2

1 reference

29 July 2017

Raul M Torres

series ordinal

3

1 reference

29 July 2017

Roberta Pelanda

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4

1 reference

29 July 2017

language of work or name

English

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publication date

22 February 2010

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Journal of Experimental Medicine

29 July 2017

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29 July 2017

207

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29 July 2017

3

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29 July 2017

607-621

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Using cells devoid of RAS proteins as tools for drug discovery

29 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

The Epstein-Barr virus Bcl-2 homolog, BHRF1, blocks apoptosis by binding to a limited amount of Bim

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Tonic B cell antigen receptor signals supply an NF-kappaB substrate for prosurvival BLyS signaling.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Heparan sulfate and heparin enhance ERK phosphorylation and mediate preBCR-dependent events during B lymphopoiesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

ITAM-mediated tonic signalling through pre-BCR and BCR complexes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Basal immunoglobulin signaling actively maintains developmental stage in immature B cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Receptor editing is the main mechanism of B cell tolerance toward membrane antigens

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Predominant autoantibody production by early human B cell precursors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Deletion of immunoglobulin beta in developing B cells leads to cell death

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

BAFF binds to the tumor necrosis factor receptor-like molecule B cell maturation antigen and is important for maintaining the peripheral B cell population

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

B cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Different sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

CD4+ T cells derived from B cell-deficient mice inhibit the establishment of peripheral B cell pools

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Activated Ras signals developmental progression of recombinase-activating gene (RAG)-deficient pro-B lymphocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Control of B cell development by Ras-mediated activation of Raf.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Evidence for a preformed transducer complex organized by the B cell antigen receptor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Self-renewal of B-1 lymphocytes is dependent on CD19.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

ras oncogenes in human cancer: a review

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Molecular components of the B-cell antigen receptor complex of the IgM class.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Analysis of the repertoire of anti-(4-hydroxy-3-nitro-phenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti-idiotope antibodies

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839140

Contribution of Receptor Editing to the Antibody Repertoire

14 July 2018

2 references

https://api.crossref.org/works/10.1084%2FJEM.20091673

21 January 2018

12 December 2020

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091673

Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091673

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091673

Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091673

Mouse anti-mouse IgD monoclonal antibodies generated in IgD-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091673

TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091673

Erk kinases link pre-B cell receptor signaling to transcriptional events required for early B cell expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091673

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091673

Stability of the B cell antigen receptor complex

21 January 2018

1 reference

12 December 2020

TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS

1 reference

12 December 2020

Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway

1 reference

12 December 2020

Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers

1 reference

12 December 2020

Cre recombinase-controlled expression of the mb-1 allele

1 reference

12 December 2020

Monoclonal antibodies specific for murine IgM I. Characterization of antigenic determinants on the four constant domains of the μ heavy chain

1 reference

12 December 2020

Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation

1 reference

12 December 2020

Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes

1 reference

12 December 2020

Negative selection of multireactive B cell clones in normal adult mice

1 reference

12 December 2020

A functional B cell receptor transgene allows efficient IL-7-independent maturation of B cell precursors

1 reference

12 December 2020

Regulation of cell survival during B lymphopoiesis: apoptosis and Bcl-2/Bax content of precursor B cells in bone marrow of mice with altered expression of IL-7 and recombinase-activating gene-2

1 reference

12 December 2020

Stochastic pairing of Ig heavy and light chains frequently generates B cell antigen receptors that are subject to editing in vivo

1 reference

12 December 2020

Ig allotypic inclusion does not prevent B cell development or response

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20091673

1 reference

29 July 2017

1 reference

29 July 2017

1 reference