Catalytic subunit of cyclic AMP-dependent protein kinase: structure and dynamics of the active site cleft (Q33716087)

28 July 2017

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title

Catalytic subunit of cyclic AMP-dependent protein kinase: structure and dynamics of the active site cleft (English)

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28 July 2017

Taylor SS

1

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28 July 2017

Radzio-Andzelm E

2

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28 July 2017

Madhusudan

3

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28 July 2017

Cheng X

4

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28 July 2017

Ten Eyck L

5

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28 July 2017

Narayana N

6

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28 July 2017

1 May 1999

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Pharmacology & Therapeutics

28 July 2017

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28 July 2017

82

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28 July 2017

133-141

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28 July 2017

2-3

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Energetic limits of phosphotransfer in the catalytic subunit of cAMP-dependent protein kinase as measured by viscosity experiments

28 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Phosphorylation modulates catalytic function and regulation in the cAMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

The glycine-rich sequence of protein kinases: a multifunctional element

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Mapping substrate-induced conformational changes in cAMP-dependent protein kinase by protein footprinting

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Functional malleability of the carboxyl-terminal tail in protein kinase A.

1 reference

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7 January 2021

Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

1 reference

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7 January 2021

Crystal structure of cyclin-dependent kinase 2

1 reference

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7 January 2021

Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity

1 reference

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7 January 2021

Structure and function of cyclic nucleotide-dependent protein kinases

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7 January 2021

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

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7 January 2021

Backbone flexibility of five sites on the catalytic subunit of cAMP-dependent protein kinase in the open and closed conformations

1 reference

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7 January 2021

Pre-steady-state kinetic analysis of cAMP-dependent protein kinase using rapid quench flow techniques.

1 reference

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7 January 2021

Kinetic analyses of mutations in the glycine-rich loop of cAMP-dependent protein kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Role of the glycine triad in the ATP-binding site of cAMP-dependent protein kinase

1 reference

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7 January 2021

Importance of the A-helix of the catalytic subunit of cAMP-dependent protein kinase for stability and for orienting subdomains at the cleft interface

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog

1 reference

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7 January 2021

Crystal structure of the tyrosine kinase domain of the human insulin receptor

1 reference

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7 January 2021

The protein kinases of budding yeast: six score and more

1 reference

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7 January 2021

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Active and inactive protein kinases: structural basis for regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Intermolecular contacts in various crystal forms related to the open and closed conformational states of the catalytic subunit of cAMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

1 reference

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7 January 2021

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1 reference

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7 January 2021

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

1 reference

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7 January 2021

2.0 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with a peptide inhibitor and detergent

1 reference

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7 January 2021

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1 reference

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7 January 2021

Identification of a partially rate-determining step in the catalytic mechanism of cAMP-dependent protein kinase: a transient kinetic study using stopped-flow fluorescence spectroscopy.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

1 reference

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7 January 2021

Principles of CDK regulation

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Staurosporine-induced conformational changes of cAMP-dependent protein kinase catalytic subunit explain inhibitory potential

1 reference

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7 January 2021

Bound to activate: conformational consequences of cyclin binding to CDK2.

1 reference

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7 January 2021

Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Conserved water molecules contribute to the extensive network of interactions at the active site of protein kinase A

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Crystal structure of the Src family tyrosine kinase Hck

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Three protein kinase structures define a common motif

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Protein kinase inhibition: natural and synthetic variations on a theme

1 reference

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7 January 2021

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Structural framework for the protein kinase family

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

A template for the protein kinase family

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https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

A conserved helix motif complements the protein kinase core

1 reference

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7 January 2021

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

1 reference

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7 January 2021

Three-dimensional structure of the tyrosine kinase c-Src

1 reference

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7 January 2021

Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2899%2900007-8

7 January 2021

Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations

1 reference

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7 January 2021

Is there a catalytic base in the active site of cAMP-dependent protein kinase?

1 reference

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7 January 2021

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

1 reference

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7 January 2021

10.1016/S0163-7258(99)00007-8

Identifiers

DOI

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28 July 2017

1 reference